Protein Alignment sNPF-R and CCHa1-R

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 136/551 - (24%)
• Similarity: 212/551 - (38%)
• Gaps: 135/551 - (24%)

  Fly     1 MANLSWLSTITTTSSSISTS--------QLPLVSTTNWSLTS--PGTTSAILADVAASDEDRSGG 55
            :|||..:.|....:..:.||        .:|.|:.|.|.|..  ..:|...|.|..:|:......
  Fly     2 IANLVSMETDLAMNIGLDTSGEAPTALPPMPNVTETLWDLAMVVSQSTQWPLLDTGSSENFSELV 66

  Fly    56 IIHNQFV-------QIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLC 113
            .....:|       .....:|:|.:||:||.||..:..|.|..|.|:.|.|.:|.:|||:|:|:.
  Fly    67 TTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVI 131

  Fly   114 VLAVPFTPLYTFMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYP---FH----- 170
            :..||.......:..|.:|..||.|..|.:..||.:|..|||:::.||||.|:.|   ||
  Fly   132 ITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGG 196

  Fly   171 ---PRMKLSTCIGIIVSIWVIALLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQG 232
               .||.|:|.    ||||::|:|..:|                    .|:.:.|...|.
  Fly   197 RRATRMTLATA----VSIWLLAILCGLP--------------------ALIGSNLKHLGI----- 232

  Fly   233 SGFIEAPDSTSATQAYMQVMTAGSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFII 297
                   :..|....|             ||     .|.| ...|.|....:...:.:.:|..:|
  Fly   233 -------NEKSIVICY-------------PY-----PEEW-GINYAKSMVLLHFLVYYAIPLVVI 271

  Fly   298 SICYVWISVKLNQRARAKPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIF---- 358
            ::.||.|::.|...| :.||.......:....||....  ::|.|.:||:.:||.:|..::
  Fly   272 AVFYVLIALHLMYSA-SVPGEIQGAVRQVRARRKVAVT--VLAFVVIFGICFLPYHVFFLWFYFW 333

  Fly   359 ----DDFDDKSNEWRFYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPCFNPSNNNII 419
                ||::      .|:.:...||:.::.:::|.||....:::..|||.|...|.|...|.
  Fly   334 PTAQDDYN------AFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYLFCRGASG---- 388

  Fly   420 NITRGYNRSDRNT-CGPRLHHGKGDGGMGGGSLDADD----QDENGITQET---CLPKEKLLIIP 476
               |...|...:| |   :|...        ||.:..    |..:...|.|   |..:|  ..|.
  Fly   389 ---RRKKRGQHDTFC---MHRDT--------SLTSTASKRFQSRHSCYQSTIRSCRLQE--TTIT 437

  Fly   477 REPTYGNGTGA-------VSPILSGRGINAA 500
            ..|..||..||       ..|:|...|.|.|
  Fly   438 TLPNGGNQNGANISAVELALPVLQAPGHNEA 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	93/358 (26%)
		TM helix 1	65..91	CDD:320331	10/25 (40%)
		TM helix 2	98..123	CDD:320331	9/24 (38%)
		TM helix 3	136..166	CDD:320331	13/29 (45%)
		TM helix 4	177..198	CDD:320331	8/20 (40%)
		TM helix 5	278..307	CDD:320331	6/28 (21%)
		TM helix 6	329..359	CDD:320331	9/37 (24%)
		TM helix 7	372..397	CDD:320331	5/24 (21%)
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	93/358 (26%)
		TM helix 1	83..109	CDD:320593	10/25 (40%)
		TM helix 2	116..142	CDD:320593	9/25 (36%)
		TM helix 3	154..184	CDD:320593	13/29 (45%)
		TM helix 4	201..221	CDD:320593	11/43 (26%)
		TM helix 5	252..277	CDD:320593	4/24 (17%)
		TM helix 6	300..330	CDD:320593	9/31 (29%)
		TM helix 7	345..370	CDD:320593	5/24 (21%)