Protein Alignment sNPF-R and Gpr165

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001100052.1
• Gene: Gpr165 / 296866
• RGDID: 1564566
• Length: 462
• Species: Rattus norvegicus
• Alignment Length: 426
• Identity: 102/426 - (23%)
• Similarity: 190/426 - (44%)
• Gaps: 101/426 - (23%)

  Fly    10 ITTTSSSISTSQLPLVSTTNWSLTSPGTTSAI-----LADVAASD---EDRSGG-----IIHNQF 61
            ||:|:|.:    |...|....::...|....:     |||..::.   .|.||.     :..::.
  Rat    40 ITSTTSQV----LQAASNAASAVGHAGRNGMLSKMDKLADHMSNTGDLADTSGPLDLEIVSQDEQ 100

  Fly    62 VQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFM 126
            ||.:..|.|..|....:.||.::.:::::.:.:.|.|.:|:.|:::::::|.:|:.|||.:....
  Rat   101 VQFWLVVGYTIVVFAAIIGNWVLNHIIMKYKRVHTATGLFVVNISVTNMMLALLSSPFTMVRYLC 165

  Fly   127 GRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPR---MKLSTCIGIIVSIWVI 188
            ....||:..|||..|||....|::.:::.:|::||:.|::||...|   |:.:.|   |:.||::
  Rat   166 NSLVFGKMTCHLSRFAQYSCAYVTVMSMAAISLDRHRVMLYPLKARITPMQGNVC---IIIIWIV 227

  Fly   189 ALLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMT 253
            :..|.:|:.:|.|:..     .:.||.|...|.|
  Rat   228 STCAALPHAVYQKLYQ-----VEFGNTTEESACL------------------------------- 256

  Fly   254 AGSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICY------VWI-----SVK 307
                 |..||.   .:..|      |.....|..|.|:||..::...|      :||     .:.
  Rat   257 -----PSFPYT---SKSTW------KYLDLGTFLLFFILPLLVLVAVYGHVAKKLWIHDAVDDIN 307

  Fly   308 LNQRARAKPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYI 372
            ::...             ..|.:||:|.:||:.:|.::.:||||:|:..:....:..|:....|
  Rat   308 IHTYI-------------CQRGKKKQTLKMLMTVVLLYTISWLPLNLYLVLLSSESISSHNGLY- 358

  Fly   373 LFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVL 408
               |..|.:|:||:||||::|.||:::||.|.:.|:
  Rat   359 ---FFLHWLAISSSCYNPYIYCWLSDSFRIEVQKVI 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	85/353 (24%)
		TM helix 1	65..91	CDD:320331	5/25 (20%)
		TM helix 2	98..123	CDD:320331	8/24 (33%)
		TM helix 3	136..166	CDD:320331	11/29 (38%)
		TM helix 4	177..198	CDD:320331	6/20 (30%)
		TM helix 5	278..307	CDD:320331	9/39 (23%)
		TM helix 6	329..359	CDD:320331	11/29 (38%)
		TM helix 7	372..397	CDD:320331	11/24 (46%)
Gpr165	NP_001100052.1	7tmA_GPR83	103..387	CDD:320511	85/353 (24%)
		TM helix 1	104..130	CDD:320511	5/25 (20%)
		TM helix 2	137..162	CDD:320511	8/24 (33%)
		TM helix 3	175..205	CDD:320511	11/29 (38%)
		TM helix 4	216..237	CDD:320511	6/23 (26%)
		TM helix 5	267..296	CDD:320511	8/34 (24%)
		TM helix 6	316..346	CDD:320511	11/29 (38%)
		TM helix 7	355..380	CDD:320511	12/28 (43%)