DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sNPF-R and Npy1r

DIOPT Version :9

Sequence 1:	NP_001262086.1	Gene:	sNPF-R / 40195	FlyBaseID:	FBgn0036934	Length:	600	Species:	Drosophila melanogaster
Sequence 2:	NP_001106828.1	Gene:	Npy1r / 29358	RGDID:	3198	Length:	382	Species:	Rattus norvegicus

Alignment Length:	359	Identity:	110/359 - (30%)
Similarity:	172/359 - (47%)	Gaps:	71/359 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 HNQFVQIFFYVL-YATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTP 121
            |.....||...| |..|.:|||.||:.:..::|:.:.|:.||||.|.||:.||:|:.|:.:|||.
  Rat    33 HLPLAVIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAVMCLPFTF 97

  Fly   122 LYTFMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYP--FHPRMKLSTCIGIIVS 184
            :||.|..|.||.::|.|..|.|..||.:|..:|..||::|:.:||.|  :.|..: ...|||.|
  Rat    98 VYTLMDHWVFGETMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNR-HAYIGITV- 160

  Fly   185 IWVIALLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYM 249
            |||:|:.:::|:.:|..:|:|                                 |....:..|:.
  Rat   161 IWVLAVASSLPFVIYQILTDE---------------------------------PFQNVSLAAFK 192

  Fly   250 QVMTAGSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARA 314
            .           .||   |.:.:||:.:|..:..:...||:..|...|.|||..|.|:|.:|...
  Rat   193 D-----------KYV---CFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYVRLKRRNNM 243

  Fly   315 KPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVN-IFDDFDDKSNEWRFYI------ 372
            ....:.|:...::   .||.|.||:::|..|.:.|||:.:.| :||        |...|
  Rat   244 MDKIRDSKYRSSE---TKRINVMLLSIVVAFAVCWLPLTIFNTVFD--------WNHQIIATCNH 297

  Fly   373 -LFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFK 405
             |.|.:.|..||.|||.||..|.:||:||:::.:
  Rat   298 NLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQ 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_001262086.1	7tm_4	75..>196	CDD:304433	50/122 (41%)
sNPF-R	NP_001262086.1	7tm_1	80..393	CDD:278431	96/322 (30%)
Npy1r	NP_001106828.1	7tmA_NPY1R	40..330	CDD:320517	108/349 (31%)
		TM helix 1	42..66	CDD:320517	8/23 (35%)
		TM helix 2	75..97	CDD:320517	11/21 (52%)
		TM helix 3	113..135	CDD:320517	8/21 (38%)
		TM helix 4	156..172	CDD:320517	8/16 (50%)
		TM helix 5	208..231	CDD:320517	6/22 (27%)
		TM helix 6	261..283	CDD:320517	8/21 (38%)
		TM helix 7	298..323	CDD:320517	11/24 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24235
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010