Protein Alignment sNPF-R and Galr3

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_062046.1
• Gene: Galr3 / 29235
• RGDID: 2658
• Length: 370
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 109/489 - (22%)
• Similarity: 183/489 - (37%)
• Gaps: 163/489 - (33%)

  Fly    29 NWSLTSPGTTSAILADVAASDEDRSGGIIHNQFVQIFFYVLYATVFVLGVFGNVLVCYVVLRN-- 91
            |.||.|||:..|:...                       |::|.:|:||:.||.||..|:|:.
  Rat     6 NISLDSPGSVGAVAVP-----------------------VIFALIFLLGMVGNGLVLAVLLQPGP 47

  Fly    92 ---RAMQTVTNIFITNLALSDILLCVLAVPF-TPLYTFMGRWAFGRSLCHLVSFAQGCSIYISTL 152
               :...:.|::||.|||::|:...:..||| ..:|| :..|.||..:|..|......::|.|:.
  Rat    48 SAWQEPSSTTDLFILNLAVADLCFILCCVPFQAAIYT-LDAWLFGAFVCKTVHLLIYLTMYASSF 111

  Fly   153 TLTSIAIDRYFVIIYPFHPR-----MKLSTCIGIIVSIWVIALLATVPYGMYMKMTNELVNGTQT 212
            ||.::::|||..:.:|...|     ......:|:   :|::|.|.:.||..|.        ||
  Rat   112 TLAAVSLDRYLAVRHPLRSRALRTPRNARAAVGL---VWLLAALFSAPYLSYY--------GT-- 163

  Fly   213 GNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGSTGPEMPYVRVYCEENWPSEQY 277
                            |..|:  :|                             .|...| .:..
  Rat   164 ----------------VRYGA--LE-----------------------------LCVPAW-EDAR 180

  Fly   278 RKVFGAITTTLQFVLPFFIIS------ICYVWISVKLNQRARAKPGSKSSRREEADRDRKKRTNR 336
            |:.....|....::||..::|      :|::|.:|          |...:...||.|....|..|
  Rat   181 RRALDVATFAAGYLLPVAVVSLAYGRTLCFLWAAV----------GPAGAAAAEARRRATGRAGR 235

  Fly   337 MLIAMVAVFGLSWLPIN-VVNIFDDFDDKSNEWRFYILFFF---------VAHSIAMSSTCYNPF 391
            .::|:.|::.|.|.|.: ::..|         |  |..|.|         .:|.:|.:::|.||.
  Rat   236 AMLAVAALYALCWGPHHALILCF---------W--YGRFAFSPATYACRLASHCLAYANSCLNPL 289

  Fly   392 LYAWLNENFRKEFKHVLPCFNPSNNNIINITRGYNRSDRNTCGPRLHHG-----------KGDGG 445
            :|:..:.:||..|:.:.||....:.:.....|...|....:.||..:.|           :||..
  Rat   290 VYSLASRHFRARFRRLWPCGRRRHRHHHRAHRALRRVQPASSGPAGYPGDARPRGWSMEPRGDAL 354

  Fly   446 MGGGSLDADDQDENGITQETCLPKEKLLIIPREP 479
            .|||              ||     :|.:.||.|
  Rat   355 RGGG--------------ET-----RLTLSPRGP 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	83/366 (23%)
		TM helix 1	65..91	CDD:320331	11/25 (44%)
		TM helix 2	98..123	CDD:320331	10/25 (40%)
		TM helix 3	136..166	CDD:320331	9/29 (31%)
		TM helix 4	177..198	CDD:320331	6/20 (30%)
		TM helix 5	278..307	CDD:320331	7/34 (21%)
		TM helix 6	329..359	CDD:320331	7/30 (23%)
		TM helix 7	372..397	CDD:320331	8/33 (24%)
Galr3	NP_062046.1	7tm_GPCRs	18..302	CDD:475119	83/389 (21%)
		TM helix 1	20..44	CDD:410628	10/46 (22%)
		TM helix 2	58..80	CDD:410628	9/21 (43%)
		TM helix 3	96..118	CDD:410628	5/21 (24%)
		TM helix 4	141..157	CDD:410628	4/18 (22%)
		TM helix 5	182..205	CDD:410628	4/22 (18%)
		TM helix 6	234..256	CDD:410628	6/21 (29%)
		TM helix 7	270..295	CDD:410628	6/24 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	317..370		16/72 (22%)