Protein Alignment sNPF-R and Grpr

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_036838.2
• Gene: Grpr / 24938
• RGDID: 2750
• Length: 384
• Species: Rattus norvegicus
• Alignment Length: 389
• Identity: 99/389 - (25%)
• Similarity: 170/389 - (43%)
• Gaps: 78/389 - (20%)

  Fly    59 NQFVQIFFYVL---YATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFT 120
            |.|.....||:   |..:.|:|:.||:.:..:....::|:.|.|:||::|||.|:||.|...|..
  Rat    34 NWFHPGIIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVD 98

  Fly   121 PLYTFMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPF-----HPRMKLSTCIG 180
            .......||.|||..|.|:.|.|..|:.:|..|||:::.|||..|:.|.     |..||:  |:.
  Rat    99 ASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKI--CLK 161

  Fly   181 IIVSIWVIALLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSAT 245
            ..: ||::::|..:|..::..:....|..|   |:|.:...
  Rat   162 AAL-IWIVSMLLAIPEAVFSDLHPFHVKDT---NQTFISCA------------------------ 198

  Fly   246 QAYMQVMTAGSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQ 310
                            ||..       .:|.:.|:....:..:.:::|..|||:.|.:|:..|.|
  Rat   199 ----------------PYPH-------SNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQ 240

  Fly   311 RARAKP--GSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFD----DKSNEWR 369
            .|...|  |:...:::...|   ||..:.::..|.:|...|||.:|:.::..:.    |.|   .
  Rat   241 SAYNLPVEGNIHVKKQIESR---KRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTS---M 299

  Fly   370 FYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPCFNPSNNNIINITRGYNRSDRNTC 433
            .:.:....|..:|.:::|.|||....|:::|||:|...|.|..||   ::|.:....||  .||
  Rat   300 LHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPS---LLNRSHSTGRS--TTC 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	87/353 (25%)
		TM helix 1	65..91	CDD:320331	7/28 (25%)
		TM helix 2	98..123	CDD:320331	11/24 (46%)
		TM helix 3	136..166	CDD:320331	12/29 (41%)
		TM helix 4	177..198	CDD:320331	5/20 (25%)
		TM helix 5	278..307	CDD:320331	7/28 (25%)
		TM helix 6	329..359	CDD:320331	8/29 (28%)
		TM helix 7	372..397	CDD:320331	6/24 (25%)
Grpr	NP_036838.2	7tmA_GRPR	42..334	CDD:320252	87/350 (25%)
		TM helix 1	43..69	CDD:320252	6/25 (24%)
		TM helix 2	76..102	CDD:320252	11/25 (44%)
		TM helix 3	114..144	CDD:320252	12/29 (41%)
		TM helix 4	156..176	CDD:320252	6/22 (27%)
		TM helix 5	208..233	CDD:320252	6/24 (25%)
		TM helix 6	258..288	CDD:320252	9/32 (28%)
		TM helix 7	302..327	CDD:320252	6/24 (25%)