Protein Alignment sNPF-R and npr-6

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_509725.2
• Gene: npr-6 / 185623
• WormBaseID: WBGene00009619
• Length: 402
• Species: Caenorhabditis elegans
• Alignment Length: 443
• Identity: 142/443 - (32%)
• Similarity: 218/443 - (49%)
• Gaps: 100/443 - (22%)

  Fly    60 QFVQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYT 124
            ::.:.||..:|..||::...||.||.|||:.|:.|||:|||||||||:|||::...::..||.||
 Worm    34 EYFRPFFISMYCAVFLVASSGNFLVVYVVMTNKRMQTITNIFITNLAVSDIMVNFTSLWLTPTYT 98

  Fly   125 FMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIY-----PFHPRMKLSTCIGIIVS 184
            .:|.|.||..|||.:...||.||:|||.|||:||||||.||::     ..:.||.:.:|:..||.
 Worm    99 SIGHWIFGGGLCHGLPLFQGTSIFISTWTLTAIAIDRYIVIVHNSSNININDRMSMRSCLSFIVL 163

  Fly   185 IWVIALLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYM 249
            ||:.:||...||.:.||:                        :::.:...|:
 Worm   164 IWLCSLLLVTPYAINMKL------------------------NYIHEPCDFL------------- 191

  Fly   250 QVMTAGSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARA 314
                             .|.|:|.:.::|.:||.:...|||:|||.:|:|.|:.|.:.||.|
 Worm   192 -----------------ICSEDWSNAEFRSIFGIVVMILQFILPFVLIAISYIKIWLFLNSR--- 236

  Fly   315 KPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYILFFFVA- 378
                :|....::|..||||..||||.||.:|.:.|.|.|::|...|. ...|..|.|..|.|::
 Worm   237 ----QSMTERKSDIKRKKRLLRMLIVMVVIFAICWFPFNLLNCLRDL-KLDNFMRGYFSFVFLSV 296

  Fly   379 HSIAMSSTCYNPFLYAWLNENFRKEFKHVLPCF---NPSNNNI-------INITRGYNRSDRNTC 433
            |.::|::|.:||.|||::||.||:||..|:||.   .|....|       ..||..:.|::|..
 Worm   297 HLMSMTATAWNPILYAFMNETFREEFAKVVPCLFARRPGTGPIRVITERTAMITNPFRRANRKK- 360

  Fly   434 GPRLHHGKGDGGMGGGSLDADDQDENGITQ---ETCLPKEKLLIIPREPTYGN 483
                              ..::|....|::   :|.:..::.::...||..|:
 Worm   361 ------------------KVEEQPVTVISESPLQTAVEPQRSIVYLDEPENGS 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	125/345 (36%)
		TM helix 1	65..91	CDD:320331	12/25 (48%)
		TM helix 2	98..123	CDD:320331	14/24 (58%)
		TM helix 3	136..166	CDD:320331	19/29 (66%)
		TM helix 4	177..198	CDD:320331	9/20 (45%)
		TM helix 5	278..307	CDD:320331	13/28 (46%)
		TM helix 6	329..359	CDD:320331	15/29 (52%)
		TM helix 7	372..397	CDD:320331	10/25 (40%)
npr-6	NP_509725.2	7tmA_NPYR-like	39..322	CDD:320331	125/344 (36%)
		TM helix 1	39..65	CDD:320331	12/25 (48%)
		TM helix 2	72..97	CDD:320331	14/24 (58%)
		TM helix 3	110..140	CDD:320331	19/29 (66%)
		TM helix 4	156..177	CDD:320331	9/20 (45%)
		TM helix 5	203..232	CDD:320331	13/28 (46%)
		TM helix 6	247..277	CDD:320331	15/29 (52%)
		TM helix 7	290..315	CDD:320331	10/24 (42%)