DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sNPF-R and npr-7

DIOPT Version :9

Sequence 1:	NP_001262086.1	Gene:	sNPF-R / 40195	FlyBaseID:	FBgn0036934	Length:	600	Species:	Drosophila melanogaster
Sequence 2:	NP_509570.3	Gene:	npr-7 / 185321	WormBaseID:	WBGene00018067	Length:	380	Species:	Caenorhabditis elegans

Alignment Length:	354	Identity:	102/354 - (28%)
Similarity:	169/354 - (47%)	Gaps:	75/354 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 YATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFMGRWAFGRS 134
            |..|..|.:.||:.|..:|:..|.|||||||||::::.:|:::...::..|||..:...|.||:.
Worm    31 YGLVGALSLVGNLAVLLIVICRREMQTVTNIFISSVSAADLVITSFSLWATPLAYYQRVWHFGKY 95

  Fly   135 LCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIWV--IALLATVPYG 197
            :|::||..||.|:....|||.::|:|||.::..||...|...||:.||..||:  .|:|:.:
Worm    96 MCYMVSIIQGLSLMWVPLTLAAVALDRYSLVASPFRQPMSKKTCLLIIAGIWMGGFAVLSPM--- 157

  Fly   198 MYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGSTGPEMP 262
              ::|.:                              |::                  |.||
Worm   158 --IRMVD------------------------------FVD------------------SYGP--- 169

  Fly   263 YVRVYCEENW--PSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRAR--AKPGSKSSRR 323
              ..:|.|:|  ..:.||..:|.....::..:|..:||:|:..|:|.||.:.:  ....|.|:..
Worm   170 --CHFCLESWDHDKQHYRLFYGLSVLVIRSAIPLVLISLCHWRIAVILNTQTKKFQTLRSASTVT 232

  Fly   324 EEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDF------DDKSNEWRFYILFFFVAHSIA 382
            :..|..||:|...:|:|||.:|.:|.||:::.|:..|.      ....:..|.:|.||  .|..|
Worm   233 QSTDIRRKQRLQTLLLAMVVIFAVSSLPLDLSNVLQDLIVVYQVRPVPDNVRHFIFFF--CHWTA 295

  Fly   383 MSSTCYNPFLYAWLNENFRKEFKHVLPCF 411
            |:.|..||.:||:.|||||::   :..||
Worm   296 MAGTLLNPLVYAYYNENFRRQ---IQTCF 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_001262086.1	7tm_4	75..>196	CDD:304433	46/122 (38%)
sNPF-R	NP_001262086.1	7tm_1	80..393	CDD:278431	90/324 (28%)
npr-7	NP_509570.3	7tmA_NPYR-like	25..317	CDD:320331	100/348 (29%)
		TM helix 1	27..51	CDD:320331	7/19 (37%)
		TM helix 2	60..82	CDD:320331	5/21 (24%)
		TM helix 3	98..120	CDD:320331	8/21 (38%)
		TM helix 4	141..157	CDD:320331	6/15 (40%)
		TM helix 5	186..209	CDD:320331	5/22 (23%)
		TM helix 6	241..266	CDD:320331	9/24 (38%)
		TM helix 7	285..310	CDD:320331	11/26 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163621
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1072979at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X589
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950