Protein Alignment sNPF-R and tkr-2

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_500930.1
• Gene: tkr-2 / 183595
• WormBaseID: WBGene00016761
• Length: 391
• Species: Caenorhabditis elegans
• Alignment Length: 396
• Identity: 95/396 - (23%)
• Similarity: 156/396 - (39%)
• Gaps: 104/396 - (26%)

  Fly    57 IHNQFVQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTP 121
            :|....|||:.:|:.....|.:.||..|.:::|.:|.|::|||.::.|||::|..:.|....|:.
 Worm    55 VHPIVSQIFYGILFTLTIFLALMGNFTVMWIILYHRQMRSVTNYYLFNLAVADASISVFNTGFSW 119

  Fly   122 LYTFMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIW 186
            .|.:...|.||...|.:.:......|..|..|:..::|:||:.||:|...|....:.:.||:.||
 Worm   120 SYNYYYVWKFGSFYCRINNLMGITPICASVFTMIVMSIERYYAIIHPLKKRPGRRSTVTIIIMIW 184

  Fly   187 VIALLATVP------------YGMYMKMTNE--LVNGTQTGNETLVEATLMLNGSFVAQGSGFIE 237
            .:|.|..||            |..|....|.  |.:....|||:|:.
 Worm   185 FMAFLFGVPAFLASKVDVYYFYDGYTLYENPLCLADNYPGGNESLLG------------------ 231

  Fly   238 APDSTSATQAYMQVMTAGSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYV 302
                        ||...|                             ..|:|::||..|:|..|.
 Worm   232 ------------QVYNNG-----------------------------LITVQYILPLCILSAAYY 255

  Fly   303 WISVKLNQRARAKPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPIN----VVNIFDDFDD 363
            .:.|:|.     |..:....|.......||:.:.||..:|.:|.:.|.|.|    .:::.:...:
 Worm   256 RVGVELR-----KDKTVGDVRHAKSVAAKKKASIMLAVVVFIFMIVWFPYNAYYLTLHLVEPIGN 315

  Fly   364 KSNEWRFYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHV---LPCFNPSNNNIINITRGY 425
            |......||..::    :.||||.:||.:|.::|:.||..|.|.   ||               :
 Worm   316 KMLSLYIYINIYW----LGMSSTVFNPVIYYFMNKRFRVGFHHAFRWLP---------------F 361

  Fly   426 NRSDRN 431
            .|||::
 Worm   362 VRSDKD 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	86/357 (24%)
		TM helix 1	65..91	CDD:320331	7/25 (28%)
		TM helix 2	98..123	CDD:320331	8/24 (33%)
		TM helix 3	136..166	CDD:320331	7/29 (24%)
		TM helix 4	177..198	CDD:320331	9/32 (28%)
		TM helix 5	278..307	CDD:320331	7/28 (25%)
		TM helix 6	329..359	CDD:320331	9/33 (27%)
		TM helix 7	372..397	CDD:320331	8/24 (33%)
tkr-2	NP_500930.1	7tmA_TACR	62..352	CDD:320512	86/357 (24%)
		TM helix 1	63..89	CDD:320512	7/25 (28%)
		TM helix 2	96..122	CDD:320512	8/25 (32%)
		TM helix 3	134..164	CDD:320512	7/29 (24%)
		TM helix 4	175..196	CDD:320512	8/20 (40%)
		TM helix 5	231..260	CDD:320512	10/87 (11%)
		TM helix 6	277..307	CDD:320512	9/29 (31%)
		TM helix 7	320..345	CDD:320512	9/28 (32%)