Protein Alignment sNPF-R and Npy1r

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_035064.1
• Gene: Npy1r / 18166
• MGIID: 104963
• Length: 382
• Species: Mus musculus
• Alignment Length: 359
• Identity: 109/359 - (30%)
• Similarity: 172/359 - (47%)
• Gaps: 71/359 - (19%)

  Fly    58 HNQFVQIFFYVL-YATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTP 121
            |.....||...| |..|.:|||.||:.:..::|:.:.|:.||||.|.||:.||:|:.|:.:|||.
Mouse    33 HLPLAVIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAVMCLPFTF 97

  Fly   122 LYTFMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYP--FHPRMKLSTCIGIIVS 184
            :||.|..|.||.::|.|..|.|..||.:|..:|..||::|:.:||.|  :.|..: ...|||.|
Mouse    98 VYTLMDHWVFGETMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNR-HAYIGITV- 160

  Fly   185 IWVIALLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYM 249
            |||:|:.:::|:.:|..:|:|                                 |....:..|:.
Mouse   161 IWVLAVASSLPFVIYQILTDE---------------------------------PFQNVSLAAFK 192

  Fly   250 QVMTAGSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARA 314
            .           .||   |.:.:||:.:|..:..:...||:..|...|.|||..|.::|.:|...
Mouse   193 D-----------KYV---CFDKFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNM 243

  Fly   315 KPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVN-IFDDFDDKSNEWRFYI------ 372
            ....:.|:...::   .||.|.||:::|..|.:.|||:.:.| :||        |...|
Mouse   244 MDKIRDSKYRSSE---TKRINIMLLSIVVAFAVCWLPLTIFNTVFD--------WNHQIIATCNH 297

  Fly   373 -LFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFK 405
             |.|.:.|..||.|||.||..|.:||:||:::.:
Mouse   298 NLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQ 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	108/350 (31%)
		TM helix 1	65..91	CDD:320331	10/26 (38%)
		TM helix 2	98..123	CDD:320331	13/24 (54%)
		TM helix 3	136..166	CDD:320331	11/29 (38%)
		TM helix 4	177..198	CDD:320331	9/20 (45%)
		TM helix 5	278..307	CDD:320331	9/28 (32%)
		TM helix 6	329..359	CDD:320331	11/30 (37%)
		TM helix 7	372..397	CDD:320331	12/31 (39%)
Npy1r	NP_035064.1	7tmA_NPY1R	40..330	CDD:320517	107/349 (31%)
		TM helix 1	41..67	CDD:320517	9/25 (36%)
		TM helix 2	74..99	CDD:320517	13/24 (54%)
		TM helix 3	112..142	CDD:320517	11/29 (38%)
		TM helix 4	153..174	CDD:320517	9/21 (43%)
		TM helix 5	207..236	CDD:320517	9/28 (32%)
		TM helix 6	255..285	CDD:320517	11/32 (34%)
		TM helix 7	298..323	CDD:320517	11/24 (46%)