Protein Alignment sNPF-R and npr-1

DIOPT Version :9

• Sequence 1: NP_001262086.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_508816.1
• Gene: npr-1 / 180752
• WormBaseID: WBGene00003807
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 483
• Identity: 134/483 - (27%)
• Similarity: 205/483 - (42%)
• Gaps: 135/483 - (27%)

  Fly    66 FYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFMGRWA 130
            |..:|..:|.||:||||.:.||...::|:.:|.||||.|||.||.::|:|::|.||:......|.
 Worm    29 FLTVYLFLFFLGLFGNVTLIYVTCSHKALLSVQNIFILNLAASDCMMCILSLPITPITNVYKNWY 93

  Fly   131 FGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIWVIALLATVP 195
            ||..||||:...||.||::.|.:|.:||:|||.:::.|....:.........|.:|:::.:.|:|
 Worm    94 FGNLLCHLIPCIQGISIFVCTFSLGAIALDRYILVVRPHSTPLSQRGAFLTTVLLWILSFVVTLP 158

  Fly   196 YGMYMKM---TNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGST 257
            |...|:|   |.|.:.|
 Worm   159 YAFNMQMIEYTEERICG------------------------------------------------ 175

  Fly   258 GPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGSKSSR 322
                    .:|.|.|.|.:.|:.:..|....|||:||.:::.||..|...|::||:.|......|
 Worm   176 --------YFCTEKWESAKSRRAYTMIVMLAQFVVPFAVMAFCYANIVSVLSKRAQTKIRKMVER 232

  Fly   323 ---------------------------REEADRDR----KKRTNRMLIAMVAVFGLSWLPINVVN 356
                                       ::|.::.|    .:||..:|:.||..||::|||.||::
 Worm   233 TSALESSCAFPSHGLEQYENELNEFLDKQEKEKQRVVLQNRRTTSILVTMVVWFGITWLPHNVIS 297

  Fly   357 IFDDFDDKSNEWRFY--------ILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVLPCF-- 411
            :..::||..:.:|.|        .|.....||||||:...||.||||||.:||   :.|:..:
 Worm   298 LIIEYDDTQSFFRLYGRDDYDISYLLNLFTHSIAMSNNVLNPVLYAWLNPSFR---QLVIKTYFG 359

  Fly   412 -NPSNNNIINITRGYNRS---DRNTCGPRLHHGKGDGGMGGGSLDADDQDE------------NG 460
             ...::.|||.|..|...   |......|...|      ||||.:|..:.|            ||
 Worm   360 DRRKSDRIINQTSVYKTKIVHDTKHLNGRAKIG------GGGSHEALKERELNSCSENLSYHVNG 418

  Fly   461 ITQ---------ETCLPK-EKLLIIPRE 478
            .|:         |...|: .||:..|.|
 Worm   419 HTRTPTPEVQLNEVSSPEISKLVAEPEE 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_001262086.1	7tm_4	75..>196	CDD:304433	46/120 (38%)
		7tm_1	80..393	CDD:278431	96/354 (27%)
npr-1	NP_508816.1	7tmA_NPYR-like	27..351	CDD:320331	110/380 (29%)
		TM helix 1	29..53	CDD:320331	11/23 (48%)
		TM helix 2	62..84	CDD:320331	12/21 (57%)
		TM helix 3	100..122	CDD:320331	9/21 (43%)
		TM helix 4	143..159	CDD:320331	3/15 (20%)
		TM helix 5	189..212	CDD:320331	7/22 (32%)
		TM helix 6	273..298	CDD:320331	12/24 (50%)
		TM helix 7	321..346	CDD:320331	13/24 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010