Protein Alignment sNPF-R and npr-16

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001355490.1
• Gene: npr-16 / 180643
• WormBaseID: WBGene00006864
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 367
• Identity: 81/367 - (22%)
• Similarity: 145/367 - (39%)
• Gaps: 81/367 - (22%)

  Fly    59 NQFVQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDI--LLCVLAVPFTP 121
            :|.:::...|.:..:..||.. |:::..:::....::::||:::..|.|:|.  |..::.|..|.
 Worm    15 SQHLRLALTVTHLLLVALGSV-NLIIILLIITRPYLRSITNVYMIGLCLADFIYLADLILVAATS 78

  Fly   122 LYTFMGR-WAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTC------- 178
            |   .|: |.||.::|||....:....|.|.|.:..:|.|||..:       .|...|
 Worm    79 L---NGKSWPFGPTICHLFHGTEATGKYASVLFVVLLAADRYIAM-------CKSDLCGRYRTYR 133

  Fly   179 IGIIVS--IWVIALLATVPYGMY---MKMTNELVNGTQT--GNETLVEATLMLNGSFVAQGSGFI 236
            ..|.:|  .|:.|.:.::|..:|   :|:.....|||.:  .|.||
 Worm   134 TAIFLSGLAWIAAFICSLPLYVYADEIKVRMRPKNGTDSIENNHTL------------------- 179

  Fly   237 EAPDSTSATQAYMQVMTAGSTGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICY 301
                                           |..:|||..:.:.:.::.:.:.|:||..:|..||
 Worm   180 -------------------------------CIAHWPSPPHAQWYISVCSVMIFILPGLVIFYCY 213

  Fly   302 VWISVKLNQRARAKPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSN 366
            ..:..||.:.|:   ||:...|.:..|...:|..|.:..:|....|.|.|..:.|:|........
 Worm   214 YHVFCKLREAAK---GSRRLHRNKRSRSSYQRVTRSVQRVVLFHLLCWSPFWLFNLFSAIFRVRI 275

  Fly   367 EWRFYILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFKHVL 408
            ..:...:...:.|.....:...||.|||:..||||..||.:|
 Worm   276 TTQLMRIIVNIIHLFPYVNCALNPVLYAYRAENFRTAFKSLL 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	77/356 (22%)
		TM helix 1	65..91	CDD:320331	4/25 (16%)
		TM helix 2	98..123	CDD:320331	8/26 (31%)
		TM helix 3	136..166	CDD:320331	10/29 (34%)
		TM helix 4	177..198	CDD:320331	6/29 (21%)
		TM helix 5	278..307	CDD:320331	6/28 (21%)
		TM helix 6	329..359	CDD:320331	7/29 (24%)
		TM helix 7	372..397	CDD:320331	6/24 (25%)
npr-16	NP_001355490.1	7tm_classA_rhodopsin-like	45..305	CDD:410626	69/322 (21%)
		TM helix 2	53..79	CDD:410626	8/25 (32%)
		TM helix 3	91..121	CDD:410626	10/36 (28%)
		TM helix 4	134..153	CDD:410626	4/18 (22%)
		TM helix 5	190..215	CDD:410626	6/24 (25%)
		TM helix 6	238..268	CDD:410626	7/29 (24%)
		TM helix 7	281..305	CDD:410626	6/23 (26%)