DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sNPF-R and XB996286

DIOPT Version :9

Sequence 1:	NP_001262086.1	Gene:	sNPF-R / 40195	FlyBaseID:	FBgn0036934	Length:	600	Species:	Drosophila melanogaster
Sequence 2:	XP_017951279.1	Gene:	XB996286 / 100491805	XenbaseID:	XB-GENE-996287	Length:	376	Species:	Xenopus tropicalis

Alignment Length:	341	Identity:	104/341 - (30%)
Similarity:	158/341 - (46%)	Gaps:	54/341 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 FFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFMGRW 129
            |....|:.|.:||:.||:.:.||:.|.:....||:|.|.|||.||:|:|...:|||.:||.|..|
Frog    34 FLGTAYSLVTILGLLGNISLMYVICRQKERGNVTHILIANLAFSDVLVCAFCLPFTAVYTVMDYW 98

  Fly   130 AFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIWVIALLATV 194
            .||.|||.:.:|.|..|:.:|.|.|..||.:||.:|::|...:..:......::.:||||.|...
Frog    99 VFGLSLCKITNFLQCASVTVSVLILVLIAFERYQLILHPTGWKPSVLQAYAAVLLVWVIASLLAF 163

  Fly   195 PYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGSTGP 259
            |....|.:|:       |.|:.:.:..     .|:|..|
Frog   164 PLASSMVLTD-------TPNKNISKVI-----GFLADKS-------------------------- 190

  Fly   260 EMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGSKSSRRE 324
                   .|.|:|.|.|....:......||:::|...|..||:.|||.|..|     |:...|.:
Frog   191 -------VCVESWSSNQQLVAYTISLQLLQYIVPLCFILGCYLRISVHLKHR-----GAMFGRND 243

  Fly   325 EADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKSNEWRFYILFFFVAHSIAMSSTCYN 389
                :..:|.|.|.:.||..|.:.|||.::.||..|:..:.....::.|.|.:.|.:||.|||.|
Frog   244 ----NHMRRVNLMFVIMVGAFAVCWLPFHIFNIIVDWHHQLIPVCYHNLIFSLCHLLAMISTCVN 304

  Fly   390 PFLYAWLNENFRKEFK 405
            |.:|..||.|.::|.|
Frog   305 PVIYGLLNSNVKREVK 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_001262086.1	7tm_4	75..>196	CDD:304433	47/120 (39%)
sNPF-R	NP_001262086.1	7tm_1	80..393	CDD:278431	93/312 (30%)
XB996286	XP_017951279.1	7tm_GPCRs	34..319	CDD:391938	102/338 (30%)
		TM helix 1	35..59	CDD:341315	8/23 (35%)
		TM helix 2	68..90	CDD:341315	11/21 (52%)
		TM helix 3	106..128	CDD:341315	7/21 (33%)
		TM helix 4	149..165	CDD:341315	5/15 (33%)
		TM helix 5	203..226	CDD:341315	5/22 (23%)
		TM helix 6	247..272	CDD:341315	9/24 (38%)
		TM helix 7	287..312	CDD:341315	11/24 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1072979at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X589
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020