DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sNPF-R and gpr83.2

DIOPT Version :9

Sequence 1:	NP_001262086.1	Gene:	sNPF-R / 40195	FlyBaseID:	FBgn0036934	Length:	600	Species:	Drosophila melanogaster
Sequence 2:	XP_002939760.1	Gene:	gpr83.2 / 100486806	XenbaseID:	XB-GENE-993677	Length:	423	Species:	Xenopus tropicalis

Alignment Length:	448	Identity:	138/448 - (30%)
Similarity:	205/448 - (45%)	Gaps:	81/448 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LSWLSTITTTSSSISTSQLPLVSTTNWSLTSPGTTSAI------LAD-VAASDEDRSGGIIHNQF 61
            |.||..:..:|....:..|...::...|...|..|...      ||| .:...:.|.|....|..
Frog     5 LMWLFLLCLSSGLKRSESLHSNASLKGSFQIPNITGFFSWNNYSLADWQSFVGKKRYGAESQNPM 69

  Fly    62 VQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPLYTFM 126
            |:....|.|:.:.|..:|||||||:||::|:.|.:.|::||.|||::|||:.:|..|||......
Frog    70 VKALLIVAYSFIIVFSLFGNVLVCHVVIKNKRMHSATSLFIVNLAVADILITLLNTPFTLARFVN 134

  Fly   127 GRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRMKLSTCIGIIVSIWVIALL 191
            ..|.||:.:||:..|||.||:::|.||||:||:||:.||::|..||:.....:..|..||::|..
Frog   135 STWMFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISTVKGVAYIAIIWIMATC 199

  Fly   192 ATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEAPDSTSATQAYMQVMTAGS 256
            .::|:.:|.|:                                         .|..|.:......
Frog   200 FSLPHAIYQKL-----------------------------------------FTFEYSEENIRSL 223

  Fly   257 TGPEMPYVRVYCEENWPSEQYRKVFGAITTTLQFVLPFFIISICYVWISVKLNQRARAKPGSKSS 321
            ..|:.|.         ||:.:.|.....|..|.:|||..|||:.|..::.||  ..|...|..::
Frog   224 CLPDFPE---------PSDLFWKYLDLATFILLYVLPLLIISVAYTTVAKKL--WLRNAIGDVTT 277

  Fly   322 RREEADRDRKKRTNRMLIAMVAVFGLSWLPIN--VVNIFDDFDDKSNEWRFYILFFFVAHSIAMS 384
            .:..|.|.:||:|.:||:.:|.:|.:.|.|:|  ||.:      .|...|.....:|..|..|||
Frog   278 EQYFALRRKKKKTIKMLMLVVVLFAVCWFPLNCYVVLL------SSQTIRTNNALYFAFHWFAMS 336

  Fly   385 STCYNPFLYAWLNENFRKEFK--------------HVLPCFNPSNNNIINITRGYNRS 428
            |||||||:|.|||:|||.|.|              |:||...||........|.:.||
Frog   337 STCYNPFIYCWLNDNFRSELKALLNMCKKPTGPSEHMLPSSVPSYRVAWPENRSFKRS 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_001262086.1	7tm_4	75..>196	CDD:304433	53/120 (44%)
sNPF-R	NP_001262086.1	7tm_1	80..393	CDD:278431	102/314 (32%)
gpr83.2	XP_002939760.1	7tmA_GPR83	72..356	CDD:320511	113/341 (33%)
		TM helix 1	73..99	CDD:320511	12/25 (48%)
		TM helix 2	106..131	CDD:320511	13/24 (54%)
		TM helix 3	144..174	CDD:320511	17/29 (59%)
		TM helix 4	185..206	CDD:320511	5/20 (25%)
		TM helix 5	236..265	CDD:320511	10/28 (36%)
		TM helix 6	285..315	CDD:320511	12/29 (41%)
		TM helix 7	324..349	CDD:320511	14/24 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000