Protein Alignment sNPF-R and tacr2

DIOPT Version :10

• Sequence 1: NP_524176.1
• Gene: sNPF-R / 40195
• FlyBaseID: FBgn0036934
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001314788.1
• Gene: tacr2 / 100002125
• ZFINID: ZDB-GENE-090312-188
• Length: 376
• Species: Danio rerio
• Alignment Length: 369
• Identity: 90/369 - (24%)
• Similarity: 151/369 - (40%)
• Gaps: 77/369 - (20%)

  Fly    49 DEDRSGGIIHNQFVQ-----IFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALS 108
            |||.:...| |.|.|     ..:.:.|..:.::...|||.|.:::|.::.|:||||.||.|||.|
Zfish    16 DEDGNETSI-NLFEQPDWQVALWAIAYTLIVIISFIGNVTVIWIILAHKRMRTVTNYFIVNLAFS 79

  Fly   109 DILLCVLAVPFTPLYTFMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRYFVIIYPFHPRM 173
            |..:......|..:|.....|.||...|...:|....:::.|..::.:||:|||..||:|..||:
Zfish    80 DASMATFNTVFNFVYALHNDWYFGLGYCKFQNFFPITAMFSSIYSMAAIAVDRYMAIIHPLKPRL 144

  Fly   174 KLSTCIGIIVSIWVIALLATVPYGMYMKMTNELVNGTQTGNETLVEATLMLNGSFVAQGSGFIEA 238
            ..:|...:|..||.:|.....|...|
Zfish   145 SSTTTKLLIGVIWTVAFSLAFPQCYY--------------------------------------- 170

  Fly   239 PDSTSATQAYMQVMTAGSTGPEMPYVRVYCEENWPSE---QYRKVFGAITTTLQFVLPFFIISIC 300
                ::|:.|              :.|..|...||.:   :::..:......|.::||..::.:.
Zfish   171 ----ASTKFY--------------FPRTVCMVEWPDDYGGKHQLSYQIAVIILIYLLPLLVMLVT 217

  Fly   301 YVWISVKLNQRARAKPGSKSSRREEADRDRKKRTNRMLIAMVAVFGLSWLPINVVNIFDDFDDKS 365
            |..:..:|  .....||..|...:. ....|::..:|:|.:|..|.:.|||.::..|...|:...
Zfish   218 YSLVGQRL--WGSEIPGEASDHYQN-QMQAKRKVVKMMIVVVTTFAICWLPYHIYFILGSFNRDI 279

  Fly   366 NEWRF----YILFFFVAHSIAMSSTCYNPFLYAWLNENFRKEFK 405
            .:..:    |:..|:    :|||||.|||.:|..||:.||..|:
Zfish   280 YKQHYIQQVYLAIFW----LAMSSTMYNPIIYCCLNQRFRSGFR 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sNPF-R	NP_524176.1	7tmA_NPYR-like	64..404	CDD:320331	82/346 (24%)
		TM helix 1	65..91	CDD:320331	6/25 (24%)
		TM helix 2	98..123	CDD:320331	10/24 (42%)
		TM helix 3	136..166	CDD:320331	8/29 (28%)
		TM helix 4	177..198	CDD:320331	6/20 (30%)
		TM helix 5	278..307	CDD:320331	4/28 (14%)
		TM helix 6	329..359	CDD:320331	9/29 (31%)
		TM helix 7	372..397	CDD:320331	10/24 (42%)
tacr2	NP_001314788.1	7tm_GPCRs	35..318	CDD:475119	82/346 (24%)
		TM helix 1	37..61	CDD:320670	5/23 (22%)
		TM helix 2	70..92	CDD:320670	9/21 (43%)
		TM helix 3	108..130	CDD:320670	3/21 (14%)
		TM helix 4	151..167	CDD:320670	4/15 (27%)
		TM helix 5	196..219	CDD:320670	3/22 (14%)
		TM helix 6	249..271	CDD:320670	7/21 (33%)
		TM helix 7	286..311	CDD:320670	11/28 (39%)