Protein Alignment CG14183 and RIX7

DIOPT Version :10

• Sequence 1: NP_649172.3
• Gene: CG14183 / 40192
• FlyBaseID: FBgn0036931
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: NP_013066.1
• Gene: RIX7 / 850625
• SGDID: S000003957
• Length: 837
• Species: Saccharomyces cerevisiae
• Alignment Length: 1002
• Identity: 172/1002 - (17%)
• Similarity: 332/1002 - (33%)
• Gaps: 362/1002 - (36%)

  Fly    41 KIYAELYVLYVELVNKL-SFIYHNTFQVQKRALVRVLVENATQQLMQLKEEL-----------KD 93
            |:.::...|...|.||: ..||            |:|.|....:...|::|.           :|
Yeast     3 KVKSKKNSLTSSLDNKIVDLIY------------RLLEEKTLDRKRSLRQESQGEEGENNEGEED 55

  Fly    94 LEMSEYIYIDKALIARKL----TPRDLVVWRSPQFLYRRPLD------IQNIIADNRLY--MNDE 146
            .::.|.::..|.|.|.::    ..:||.:.|..:.:.::.:|      |::.:.:...|  .|:|
Yeast    56 EDIFESMFFAKDLTAGEIFTFCLTKDLSLQRVKKVVLQKTIDRMLKDVIESELEEFGSYPGYNNE 120

  Fly   147 EKEEKAAQDWVPISEAVKLIQAHERARRARVYKSNIKYDKKKFLKVHQRKKINYKFTFKPDQAMS 211
            |:|:.:.::                           :..||..:......::|.:.|
Yeast   121 EEEKPSLEE---------------------------ELAKKNMMIERDTNEMNKRIT-------- 150

  Fly   212 IPVKRTIFSADFLKADESCENLIKKDDVADTAIDDEEALSAIQNNAACKIQSCWRGYKTRKIVKI 276
                     :.:.|:....|::.:.||.                             ||.::.|.
Yeast   151 ---------STWSKSGSVSESITETDDP-----------------------------KTEEVKKS 177

  Fly   277 RKRFKEELYGMKKIRKLKR----PNQTANS----------IMEMYKNEMLKKKLDEDFIN----- 322
            :||.||....:|: :|:|.    ||.:..|          :||:....:|..::   |::
Yeast   178 KKRSKEGTCKVKR-QKIKEDRSPPNSSLKSLGGMDDVVAQLMELIGLPILHPEI---FLSTGVEP 238

  Fly   323 --------------------LINDERTRLLQFRSPWMMEDISDHIRAWFKEFYDATGNFHPYPDP 367
                                |..:.:...:...:|.::..:|.......::.:|...:..|
Yeast   239 PRGVLLHGPPGCGKTSIANALAGELQVPFISISAPSVVSGMSGESEKKIRDLFDEARSLAP---- 299

  Fly   368 VKQGTVLVVIDE--TMTPME---FQESLGKKPLSKAELKKLRDKEKKEKRKKKEKL------KQL 421
                 .||..||  .:||..   .|..:.::.:  |:|....|:...||...|..:      :..
Yeast   300 -----CLVFFDEIDAITPKRDGGAQREMERRIV--AQLLTSMDELTMEKTNGKPVIIIGATNRPD 357

  Fly   422 KMKEAKRR----------------------KKLRD----AGVID-----------IGYELTA--- 446
            .:..|.||                      ||:.|    .|.||           :|.:|.|
Yeast   358 SLDAALRRAGRFDREICLNVPNEVSRLHILKKMSDNLKIDGAIDFAKLAKLTPGFVGADLKALVT 422

  Fly   447 ---SKAIENIEETMKKY----------SKDWRNVDEYLN------KNH----DPIKEWVTEEQLA 488
               :.||:.|.:|....          |:|...:||..|      ||.    ||:...|.::.:.
Yeast   423 AAGTCAIKRIFQTYANIKSTPTTATDSSEDNMEIDETANGDESSLKNTANMIDPLPLSVVQQFIR 487

  Fly   489 KIHQEVRGLVDEYMRVEYELLREALAKDNDEKYKALKVKYPKKKKEKRKKKPKDMTGDRTLESLY 553
            ...:.:.|.....:.::||           :..|||....|..|:|.....| |:|
Yeast   488 NYPEPLSGEQLSLLSIKYE-----------DFLKALPTIQPTAKREGFATVP-DVT--------- 531

  Fly   554 NELKDAGIIEEIGHRDFDEFITDFNFVADDTRDEDGLTTLGPAKGDIKMVIQESMLGMGEFDVPK 618
              ..:.|.::.:                   |.|..:..:.|.|   :..:.|.:      .:..
Yeast   532 --WANVGALQRV-------------------RLELNMAIVQPIK---RPELYEKV------GISA 566

  Fly   619 PKSLLLIGPLNSGKRLLCEIIASELDAVFMNL-SPENTYKYAKDLKYFLHVILKVAKAFQPTIMY 682
            |..:||.||...||.||.:.:|:|..|.|::: .||...||..:.:..:..:...|:|..|.:::
Yeast   567 PGGVLLWGPPGCGKTLLAKAVANESRANFISIKGPELLNKYVGESERSIRQVFTRARASVPCVIF 631

  Fly   683 IEEAHRLFWKKVP---PEAVEINPRLLGTSLASKILKPLKKNDKIVLVGTSNMPWAANGGIKRA- 743
            .:|...|    ||   ....|.:.|::.|.|..  |..|.....|.::|.:|.|...:..:.|.
Yeast   632 FDELDAL----VPRRDTSLSESSSRVVNTLLTE--LDGLNDRRGIFVIGATNRPDMIDPAMLRPG 690

  Fly   744 ------------------------------------FQKVLLIPKC-DYGTSFLLWLELMTENAP 771
                                                |::::...|| ::..:.|..|
Yeast   691 RLDKSLFIELPNTEEKLDIIKTLTKSHGTPLSSDVDFEEIIRNEKCNNFSGADLAAL-------- 747

  Fly   772 DDMKEYAYSALARVLQAYNSGDID---DNVKETLNIDRKMRLKNEALDPNEFL------EYFLSK 827
              ::|.:..||.|  :.:.|.:|.   ||     ::|::....:..:...|.:      ...|.|
Yeast   748 --VRESSVLALKR--KFFQSEEIQSVLDN-----DLDKEFEDLSVGVSGEEIIVTMSDFRSALRK 803

  Fly   828 NEPPIFPPDEKIMDKFNKWFGSSNKLE 854
            .:|.:...|....|:.||..|.:.:::
Yeast   804 IKPSVSDKDRLKYDRLNKKMGLTEEMK 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14183	NP_649172.3	Adgb_C_mid-like	<201..>278	CDD:412094	8/76 (11%)
		globin helix H	201..232	CDD:412094	2/30 (7%)
		IQCD	247..278	CDD:467745	3/30 (10%)
		IQ motif	259..277	CDD:412094	3/17 (18%)
		P-loop containing Nucleoside Triphosphate Hydrolases	617..750	CDD:476819	36/173 (21%)
RIX7	NP_013066.1	CDC48	<192..824	CDD:273521	128/719 (18%)