DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14183 and SPATA5L1

DIOPT Version :9

Sequence 1:	NP_649172.3	Gene:	CG14183 / 40192	FlyBaseID:	FBgn0036931	Length:	872	Species:	Drosophila melanogaster
Sequence 2:	NP_076968.2	Gene:	SPATA5L1 / 79029	HGNCID:	28762	Length:	753	Species:	Homo sapiens

Alignment Length:	359	Identity:	72/359 - (20%)
Similarity:	144/359 - (40%)	Gaps:	65/359 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   542 DMTG---DRTLESLYNELK--DAGIIEEIGHRDFDEFITDF-NFVADDTRDEDGLTTLGPAK--- 597
            |:|.   :..:.:|.:..|  |..:|:||      :|:..| |......|...||..:.|..
Human   407 DLTALCREAAMHALLHSEKNQDNPVIDEI------DFLEAFKNIQPSSFRSVIGLMDIKPVDWEE 465

  Fly   598 ----GDIKMVIQESM----------LGMGEFDVPKPKSLLLIGPLNSGKRLLCEIIASELDAVFM 648
                .|:|:.:::|:          :.||   :.:||.:||.||....|..|...:|:.....|:
Human   466 IGGLEDVKLKLKQSIEWPLKFPWEFVRMG---LTQPKGVLLYGPPGCAKTTLVRALATSCHCSFV 527

  Fly   649 NLSPENTYK-YAKDLKYFLHVILKVAKAFQPTIMYIEEAHRLFW-KKVPPEAVEINPRLLGTSLA 711
            ::|..:.:. :..|.:..|..|.:.|:|..|.|::::|...:.. :.......::..|:|.. |.
Human   528 SVSGADLFSPFVGDSEKVLSQIFRQARASTPAILFLDEIDSILGARSASKTGCDVQERVLSV-LL 591

  Fly   712 SKI----LKPLKK--------------NDKIVLVGTSNMPWAANGGIKR--AFQKVLLIPKCDYG 756
            :::    ||.:::              |..::::..:|.|...:..:.|  ...|::.||..|:
Human   592 NELDGVGLKTIERRGSKSSQQEFQEVFNRSVMIIAATNRPDVLDTALLRPGRLDKIIYIPPPDH- 655

  Fly   757 TSFLLWLELMTENAPDDMKEYAYSALARVLQAYNSGDIDDNVKETLNIDRKMRLKNEALDPNEF- 820
            ...|..|::.|:..|.. .:.:...||.....::..|:.:...|.    ..:.|:...||....
Human   656 KGRLSILKVCTKTMPIG-PDVSLENLAAETCFFSGADLRNLCTEA----ALLALQENGLDATTVK 715

  Fly   821 LEYFLSK---NEPPIFPPDEKIMDKFNKWFGSSN 851
            .|:||..   .:|.:...|..:.:...|..|.||
Human   716 QEHFLKSLKTVKPSLSCKDLALYENLFKKEGFSN 749

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14183	NP_649172.3	AAA	622..751	CDD:278434	27/150 (18%)
SPATA5L1	NP_076968.2	CDC48	22..746	CDD:273521	69/354 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	171..203
		AAA	237..367	CDD:278434
		AAA	501..651	CDD:278434	27/150 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900