DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14183 and fign

DIOPT Version :9

Sequence 1:	NP_649172.3	Gene:	CG14183 / 40192	FlyBaseID:	FBgn0036931	Length:	872	Species:	Drosophila melanogaster
Sequence 2:	XP_021334341.1	Gene:	fign / 553599	ZFINID:	ZDB-GENE-050522-339	Length:	747	Species:	Danio rerio

Alignment Length:	342	Identity:	75/342 - (21%)
Similarity:	131/342 - (38%)	Gaps:	84/342 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   550 ESLYNELKDAGIIEEIGHRDFDEFITDFNFVADDTRDEDGLTTLGPAKGDIKMVIQESMLGMGEF 614
            |.|.|  .||.::         |.:|..........|...:..|..||..||..:...:|....|
Zfish   448 EQLKN--SDASLV---------EMVTTEILQQTPPVDWSDIAGLEMAKATIKDEVLWPILRPDMF 501

  Fly   615 D--VPKPKSLLLIGPLNSGKRLLCEIIASELDAVFMNLSPEN-TYKYAKDLKYFLHVILKVAKAF 676
            .  ...|:|:||.||..:|:.||...:||:|.|.|:.||... ..|:..:.:..:.....:|:..
Zfish   502 SGLATLPRSILLFGPQGTGRTLLGRCMASQLGAAFLLLSGSALVTKWLGEGEKIVQASFLIARCR 566

  Fly   677 QPTIMYIEEAHRLFWKKVPPEAVEINPRLLGTSLASKILKPL-----KKNDKIVLVGTSNMPWAA 736
            ||::::|.:...|...::..|: .:|      .:.|::|..|     ...:.:::|.:::.|...
Zfish   567 QPSVVFISDVDLLLSSQLSEES-PVN------RIKSELLLQLDGVLSSPEEHVLVVCSTSKPEEI 624

  Fly   737 NGGIKRAFQKVLLIPKCDYGTSFLLWLELMTENAPDDMKEYAYSALARVLQAYNSGDIDDNVKET 801
            :..::|.|.|.||:|                  .||....  :..::::|..:|....|..|  |
Zfish   625 DESLRRYFVKRLLVP------------------LPDATAR--HQIISQLLSQHNYCLSDKEV--T 667

  Fly   802 LNIDRK--------MRLKNEAL---------------DPNEF-------LEYFLSKNEPPIFPPD 836
            |.:.|.        :||..|||               .|.:.       .|....|.:|.|   .
Zfish   668 LLVQRTDGFSGLDVVRLCQEALVGPLHGMPGADLSGMIPGQMRPVSYQDFENVFCKIQPSI---S 729

  Fly   837 EKIMDKFNKW---FGSS 850
            :|.:|.:.:|   ||.|
Zfish   730 QKELDTYTEWNKMFGCS 746

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14183	NP_649172.3	AAA	622..751	CDD:278434	32/134 (24%)
fign	XP_021334341.1	EBV-NA3	<174..300	CDD:332796
		Herpes_UL32	<270..>444	CDD:283680
		SpoVK	<464..734	CDD:223540	63/301 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900