Protein Alignment CG14183 and drc11

DIOPT Version :10

• Sequence 1: NP_649172.3
• Gene: CG14183 / 40192
• FlyBaseID: FBgn0036931
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: XP_073809094.1
• Gene: drc11 / 553364
• ZFINID: ZDB-GENE-050208-768
• Length: 846
• Species: Danio rerio
• Alignment Length: 917
• Identity: 247/917 - (26%)
• Similarity: 424/917 - (46%)
• Gaps: 159/917 - (17%)

  Fly    20 LIKKQNRLKKIEPPEEKAVSYKIYAELYVLYVELVNKLSFIYHNTFQVQKRALVRVLVENATQQL 84
            |::.:....::.|.:::...::..|..::.|:::...|..:|......|||.:|..:::....:|
Zfish    20 LLEDEYPTLELRPQKDRLQVFQTLATFFLRYMKIFRALEEVYDQIVHPQKRRVVHQVLDGVMGRL 84

  Fly    85 MQLKEELKDLEMSEYIYIDKALIARKLTPRDLVVWRSPQFLYRRPL----DIQNIIADNRLYMND 145
            ::||.|:.:||.||:.|.|..|...|:||.||.| ..|::..|..:    :.:.::|  .:...:
Zfish    85 VELKNEMVELEHSEFHYFDDLLQDFKMTPEDLEV-PIPRYFVREKMRALKEREKMLA--HVLAKE 146

  Fly   146 EEKEEKAAQDWV---PISEAVKLIQAHERARRARVYKSNIKYDKKKFLKVHQRKKINYKFTFKPD 207
            ...|.|:....|   .:..||.|:|..||||:.|             |:.|..|.|
Zfish   147 GRPEHKSVNRPVLSMSMERAVWLLQVSERARQGR-------------LRAHFMKTI--------- 189

  Fly   208 QAMSIPVKRTIFSADFLKADESCENLIKKDDVADTAIDDEEALSAIQNNAACKIQSCWRGYKTRK 272
                             :.:|...:|      ..:.:|.::|       |.| ||..||||:.|:
Zfish   190 -----------------RLEEQRRHL------GSSMLDPDQA-------ATC-IQKVWRGYRDRR 223

  Fly   273 IVKIRKRFKEELYGMKKI---RKLKRPNQTANSIMEMYKNEMLKKKLDEDF----INLINDERTR 330
              ::.|...||:..:..|   ::...|.|.....:|. :..:::::.:.::    :|:....||
Zfish   224 --RVNKECLEEMIFLGMIPAQQQTPSPAQLRAQQVER-RRHIIQEEHEAEYQTALVNIKESVRT- 284

  Fly   331 LLQFRSPWMMEDISDHIRAWFKEFYDATGNFHPYPDPVKQGTVLVVIDET--MTPMEFQESLGKK 393
               .....:.|.:.:.||.||.|..||:|.|..:|.|...|:..:...:|  ....||
Zfish   285 ---VDGADIKESLQEQIRQWFLECRDASGKFPDFPSPEDGGSASIFAQKTPEQVAAEF------- 339

  Fly   394 PLSKAELKKLRDKEKKEKRKKKEKLKQLKMKEAKRRKKLR-----------DAGVIDIGYELTAS 447
                        ..|:|:|:||:|||..|.|:|..||:.:           |....:.|:::|.|
Zfish   340 ------------AAKEEEREKKKKLKSEKDKKANDRKEKKKGKPKGKGGKGDTEEEETGWKMTPS 392

  Fly   448 KAIENIEETMKKYSKDWRNVDEYLNKNHDPIKEWVTEEQLAKIHQEVRGLVDEYMRVEYELLREA 512
            ..:..:.|..|.|.:.|:|.||..|.......:.|.||:..::..|:|..|||.||.|.:.|:..
Zfish   393 NFLPTVFEGAKLYKEVWQNRDEQQNFLQRFDAQLVREEKRLEVEVELRVQVDELMRQELKNLKLV 457

  Fly   513 LAKDNDEKYKALKVKYPKKKK------EKRKKKPKDMTGDRTLESLYNELKDAGIIEEIGHRDFD 571
            :.:|..:|.|.:|....||||      :|:|||.||:|.|||:||||.||...|||....:....
Zfish   458 VDRDKGKKKKKVKKSSKKKKKKGRKTGKKKKKKEKDLTADRTIESLYEELVLEGIIIRPMNVKLS 522

  Fly   572 EFITDFNFVADDTRDEDGLTTLGPAKGDIKMVIQ-ESMLGMGEFDV----PKPKSLLLIGPLNSG 631
            ::|.:::::....|..| :..: |:..|::.:|. ..:|.:|...|    |..::|||.||...|
Zfish   523 DYIGEYSYLGTTLRQAD-IEPM-PSLSDVRQLIALYGILPLGSQCVHERGPLIRALLLTGPQGVG 585

  Fly   632 KRLLCEIIASELDAVFMNLSPE---NTYKYAKDLKYFLHVILKVAKAFQPTIMYIEEAHRLFWKK 693
            |::|...:.:|..|...||||.   ..|.....|:..||::.|||:..||::::|.:|.:.|:||
Zfish   586 KKMLVHALCTETGANLFNLSPSTLAGKYPGKSGLQLLLHMVFKVARQLQPSVIWIGDAEKTFYKK 650

  Fly   694 VPPEAVEINPRLLGTSLASKILKPLKKNDKIVLVGTSNMPWAANGGIK---RAFQKVLLIPKCDY 755
            ||....|:.|:.|..:| .||||.:|..|::::||||..|:.|:  ||   :.::|::|||:.||
Zfish   651 VPKLEKEMEPKRLKKTL-PKILKSIKAEDRVLVVGTSRRPFDAD--IKPFCKVYKKIILIPRPDY 712

  Fly   756 GTSFLLWLELMTENAPDDMKEYAYSALARVLQAYNSGDIDDNVKETLNIDRKMRLKNEALDPNEF 820
            .:.|.||.||:..:......:...|:||:|...|..|.|...: :|:.|..::.|  :|..|...
Zfish   713 ASRFTLWKELLQAHGALLDPKLDLSSLAKVTDGYTQGHILQAI-QTILIPHRLEL--QAKRPLTA 774

  Fly   821 LEYF--LSKNEPPIFPPDEKIMDKFNKWFGSSNKLEKLR------------------KSYMAQKL 865
            :|:.  |::.: |::..:|   :.|..|: |...|.|.|                  |....||.
Zfish   775 VEFIPPLARQD-PVYKEEE---ESFKAWY-SRTPLGKKRARAAKASEEQAILKKGKTKGGKLQKK 834

  Fly   866 AKASKKK 872
            .|..|||
Zfish   835 GKEGKKK 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14183	NP_649172.3	Adgb_C_mid-like	<201..>278	CDD:412094	13/76 (17%)
		globin helix H	201..232	CDD:412094	1/30 (3%)
		IQCD	247..278	CDD:467745	10/30 (33%)
		IQ motif	259..277	CDD:412094	8/17 (47%)
		P-loop containing Nucleoside Triphosphate Hydrolases	617..750	CDD:476819	50/138 (36%)
drc11	XP_073809094.1	None