Protein Alignment CG14183 and Iqca1l

DIOPT Version :9

• Sequence 1: NP_649172.3
• Gene: CG14183 / 40192
• FlyBaseID: FBgn0036931
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: NP_001019488.2
• Gene: Iqca1l / 499971
• RGDID: 1564789
• Length: 822
• Species: Rattus norvegicus
• Alignment Length: 921
• Identity: 251/921 - (27%)
• Similarity: 443/921 - (48%)
• Gaps: 149/921 - (16%)

  Fly     1 MSFDLNHKFWVYTRKEIGKLIKKQ-NRLKKIEPPEEKAVSYKIYAELYVLYVELVNKLSFIYHNT 64
            ||.....:.|..:...:.::::|: :.|:.:...|.::..|:| :.||:.|:.|:.:.:..|...
  Rat     1 MSEGTYQRLWEASHATLEEVLEKEPSPLEPVLTRERQSFQYRI-SVLYLYYLGLLRRFNLAYDQM 64

  Fly    65 FQVQKRALVRVLVENATQQLMQLKEELKDLEMSEYIYIDKALIARKLTPRDLVVWRSPQF----- 124
            .|.|||.|:|.|::....::::||:||..:::.|...:|:.|...||||.||.| ..|::
  Rat    65 VQPQKRRLLRRLLDGVAGRVLELKDELVRVDLCETHCLDRVLQELKLTPADLEV-PIPKYFQLEQ 128

  Fly   125 ---LYRRPLDIQNIIADNRLYMNDEEKEEKAAQD---WVPISEAVKLIQAHERARRARVYKSNIK 183
               :..|...:..|:|  ||       |..|:|:   .:..:||:.::|..||||:.|:
  Rat   129 TSTMKARQQMLAEILA--RL-------EPLASQENLRGMSRTEALIIVQCAERARQGRL------ 178

  Fly   184 YDKKKFLKVHQRKKINYKFTFKPDQAMSIPVKRTIFSADFLKADESCENLIKKDDVADTAIDDEE 248
                                                .|.|::.       |:|::..|..|.:..
  Rat   179 ------------------------------------RATFMRE-------IRKEEERDRRIRENG 200

  Fly   249 ALSAIQNNAACKIQSCWRGYKTRKIVKIRKRFKEELYGMKKIRKLKRPNQTA--NSIMEMYKNEM 311
            .....|:..|..||..|:||..||.::..:|.:.|..||     |...:||.  |::.:.:..|.
  Rat   201 RQKFSQDQGAIVIQKVWKGYLQRKRIEQDRRMEMEFIGM-----LPSSSQTTRQNALAQAFVGEE 260

  Fly   312 LKK----KLDEDFINLINDERTRLLQFRSPWMMEDISDHIRAWFKEFYDATGNFHPYPDPVKQGT 372
            .::    :.:|:|...|......|.:...|.|.|.:.|.||.||.|.:..||.|..|||....|:
  Rat   261 SRRTRQVEKEEEFQEAIAKTHESLTETEGPDMKERMKDQIRQWFIECHALTGRFPDYPDEASGGS 325

  Fly   373 VLVVIDETMTPMEFQESLGKKPLSKAELKKLRDKEKKEKRKKKEKLKQLKMKEAKRRKKLRDAGV 437
            .|:..|:  ||.:.::.|.         .:.::.:|||:.|.|:|:|:.|.|:.|:.|:.:....
  Rat   326 YLIFADK--TPEQVRQELE---------AQAQENKKKEQEKNKDKVKEKKEKKKKKTKEEKAKKD 379

  Fly   438 IDIGYELTASKAIENIEETMKKYSKDWRNVDEYLNKNHDPI--KEWVTEEQLAKIHQEVRGLVDE 500
            .::.:::..||:|..|....::::..|::  .|.||:....  .|.:.||:..::..|:|..|||
  Rat   380 PEVMFKVLPSKSIPVINAGHEEFTSIWKS--RYDNKHPSQSFDSETLREEKRKQVEMEIRVQVDE 442

  Fly   501 YMRVEYELLREALAKDNDEKYKALKVKYPKK---KKEKRKKKPKDMTGDRTLESLYNELKDAGII 562
            .||.|...||  ||.|.:|   ...:|.|||   ||..:|||.||:|.||:::||:.||...|:|
  Rat   443 LMRQELRNLR--LAVDREE---TRPLKSPKKKGGKKSGKKKKEKDLTPDRSVDSLFEELVVIGLI 502

  Fly   563 EEIGHRDFDEFITDFNFVADDTRDEDGLT-TLG-----PAKGDIKM-VIQESMLGMGEFDV---- 616
            ::......:::|.|..::        |.| ||.     |:..||:. :....:|.:|..|:
  Rat   503 KKSLLVTLNDYIGDCLYL--------GSTLTLANKIPMPSLFDIRQNIALYGVLRLGSHDIHTMA 559

  Fly   617 PKPKSLLLIGPLNSGKRLLCEIIASELDAVFMNLSPENT---YKYAKDLKYFLHVILKVAKAFQP 678
            |..:|:||:||...||::|.:.:.:|..|...:|||.|.   |......:..:|::.|||:.|||
  Rat   560 PLVRSILLVGPSGMGKKMLVQAVCTETGANLFDLSPGNVMGKYPGKNGSQLLMHIVFKVARVFQP 624

  Fly   679 TIMYIEEAHRLFWKKVPPEAVEINPRLLGTSL--ASKILKPLKKNDKIVLVGTSNMPWAAN-GGI 740
            ::::|....:.|:||:|.|...::|:.:...|  |::.|.|   .|:::|:||:..|..|. .|:
  Rat   625 SVIWIGNTEKTFYKKIPKEERRMDPKRIKKDLMRATRQLGP---GDRVMLIGTTERPQLAEMKGL 686

  Fly   741 KRAFQKVLLIPKCDYGTSFLLWLELMTEN---APDDMKEYAYSALARVLQAYNSGDIDDNVKETL 802
            .|.::::|.||:.||.:.::|| :.|.||   .....:....||||||...|..|.|..:::..|
  Rat   687 CRFYERILFIPRPDYASRYVLW-KRMIENQGIGVQQTQSLDISALARVSDGYTPGHILQSIQSVL 750

  Fly   803 NIDRKMRLKNEALDPNEFLEYFLSKNEPPIFPPDEKIMDKFNKWF-----GSSN-KLEKLRKSYM 861
            ...|.::|..:.|..:||:.: |:|.: |::..:|   :...:||     |..| |..|.::...
  Rat   751 TERRLLQLTKKPLVASEFVVH-LAKLD-PVYREEE---ESLKEWFYKTPLGKKNIKFTKDQQEAE 810

  Fly   862 AQKLAKASKKK 872
            ..:|||..|||
  Rat   811 EARLAKEKKKK 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14183	NP_649172.3	AAA	622..751	CDD:278434	41/134 (31%)
Iqca1l	NP_001019488.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..378		12/48 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	457..484		12/29 (41%)
		SpoVK	<563..738	CDD:223540	57/178 (32%)
		AAA	565..698	CDD:278434	42/135 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339082
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D127946at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103079
Panther	1	1.100	-	-	O	PTHR14690
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.710