Protein Alignment CG14183 and Pex1

DIOPT Version :9

• Sequence 1: NP_649172.3
• Gene: CG14183 / 40192
• FlyBaseID: FBgn0036931
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Alignment Length: 1063
• Identity: 192/1063 - (18%)
• Similarity: 357/1063 - (33%)
• Gaps: 349/1063 - (32%)

  Fly    28 KKIEPPEEKAVSYKIYAELYVLYVELVNKLS-----FIYHNTFQVQKRALVRVLVENATQQLMQL 87
            |:|...|...|...:.|::..|....|..:|     .|..:|.::....|.:..:.|:||.|:
  Fly    71 KEIGLHENDLVKCALIADVLNLRSVHVTPVSSKDWEIIELSTEKISGSVLEQTRIVNSTQILI-- 133

  Fly    88 KEELKDLEMSEYIYIDK----ALIARKLTPR----------DLVVWRSPQFLYRRPLDIQN---- 134
                        ::|:|    ||...:|.|.          :|||  :|. ||:   .:.|
  Fly   134 ------------VWINKSMQVALTVDRLKPHMNYGRIDHNTELVV--APN-LYK---GLTNGTSN 180

  Fly   135 -IIADNRLYMNDE---EKEEKAAQDWVPISEAVKLIQAHERARRARVYKSNIKYDKKKFLKVHQR 195
             :|.:|......:   :.:::..:...|::.:..:.......:|      |.:.|..:.||...|
  Fly   181 GVIEENTKLSRSKTTAQVKDELTEKLTPLTHSSTVSNVKNTIQR------NKRQDHMERLKKDLR 239

  Fly   196 KKINYKFTFK------PDQAMSIPV-----------KRTIFSADFLKADESCENLIKKDDVADTA 243
            ::.:..|.|:      .:||....|           ...:|......||:  :..::...|.|..
  Fly   240 RESSRSFEFRVIRGLWREQAQESDVFVNGKHLPEFFDLDLFYCMHTAADK--DYYVRVRTVEDDI 302

  Fly   244 IDD--EEALSAIQNNAACKIQSCWRGYKTRKIVKIRKRFKEELYGMKKI-RKLKRPNQTANSI-- 303
            .||  |....:|:.||              .::|        |.|:|:: |.:.||..|..:.
  Fly   303 EDDLPETIHPSIELNA--------------NLMK--------LLGIKELERVVLRPKTTVVNFVE 345

  Fly   304 -MEMYKNEMLKKKLDEDFINLINDERTR----LLQFRSPWMMED--------ISDHIR------A 349
             :|::.|:....|:.|:.......|||:    |........:||        :.:|.|      .
  Fly   346 KIELFANKKTHYKIMENAFKRFVIERTQHKPMLFNQEEVVRLEDDLLVTVGILPEHFRYCVVDAQ 410

  Fly   350 WFKE--FYDATGNFHPYPDPVKQGTVLVVIDETMTPMEFQESLGKKPLSKAELKKLRDKEKKEKR 412
            :.||  .|.|        |.|:  .|..:|.|...|        ..|||..:|.:|.:.:|
  Fly   411 FLKESKIYAA--------DLVR--PVGEIIKEETPP--------TSPLSVQDLIQLPEYDK---- 453

  Fly   413 KKKEKLKQLKM-------KEAKRRKKLRDAGVIDIGYELTASKAIENIE---------------- 454
            ...:.:::|:|       ....|:..:..||....|..:...:.::.:.
  Fly   454 IVDQVVQELRMNLCLSADNSVMRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHFEFFHGSRS 518

  Fly   455 --ETMKKYSKDWRNV-------------------------------DEYLNKNHDPIKEWV---- 482
              ...:...||.||:                               .||.|:..|.:.:.:
  Fly   519 KGRKTESIQKDLRNIFTSCLQHAPAIVVLENLDVLAHAAGEQSSQDGEYYNRMADTVYQLIVQYT 583

  Fly   483 ---------TEEQLAKIHQEV---RG--------LVDEYMRVEYE-LLREA-----LAKDNDEKY 521
                     |..:|..:::.:   ||        .:....|.:.| :|||.     :|||.|
  Fly   584 TNNAIAVIATVNELQTLNKRLSSPRGRHVFQTVARLPNLERADREIILRELCSHINVAKDLD--- 645

  Fly   522 KALKVKYPKKKKEKRK------------------KKPKDMTGDRTLESLYNE----LKDAGIIEE 564
               .||:....:..||                  |....:|.|:.:|||.:.    |:.....:.
  Fly   646 ---LVKFSNLTEGYRKCDLVQFVERAIFYAYRISKTQPLLTNDQLIESLEHTNSYCLQGIQSNQR 707

  Fly   565 IGHRDFDEFITDFNFVADDTRDEDGLTTLGPAKGDIKMVIQESMLGMGEF-------DVPKPKSL 622
            .|: |.|         |::.|.|:     .|....:..|::|.::....:       .:.....:
  Fly   708 TGN-DAD---------ANEMRVEE-----LPGLESVVGVLEEVLMWPSRYPTIFNASPLRNQAGV 757

  Fly   623 LLIGPLNSGKRLLCEIIASELDAVFMNL-SPENTYKYAKDLKYFLHVILKVAKAFQPTIMYIEEA 686
            ||.||..:||..|...:|:..:...::: .||...||....:..:..:...|::.:|.:::.:|.
  Fly   758 LLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEENVRNLFNRARSARPCVLFFDEF 822

  Fly   687 HRLFWKK---------------------------VPPEAVEINPRLLGTSL--ASKILKPLKKND 722
            ..|..|:                           |...|....|.||..:|  :.:|       |
  Fly   823 DSLAPKRGHDSTGVTDRVVNQLLTELDGVEGLQGVTVIAATSRPELLDPALLRSGRI-------D 880

  Fly   723 KIVLVGTSNMPWAANGGIKRAFQKVLLIPKC-DYGTSFLLWLELMTENAPDDMKEYAYSALARVL 786
            ::|.....:.|  |...|..|....|.:.:| |:.     |....|.|       |..:.:..:|
  Fly   881 RLVECPLPDAP--ARVRIFEALSSTLSLDECVDFD-----WFAGKTAN-------YTGADIQSIL 931

  Fly   787 QAYNSGDIDDNVKETL------NIDRKMRLKNEALDPNEFLEYFLSKNEPPIFPPDEKIMDKFNK 845
            .:.|..    .|||.|      .:.:|:.||.:.|     :|.| ....|.:...|   :.|:::
  Fly   932 TSANMA----AVKEALAQFGHEKLAKKISLKQKHL-----IESF-QTTRPSLSASD---VAKYHR 983

  Fly   846 WFGSSNKLEKLRKSYMAQKLAKA 868
            .:......||..:.::|::...|
  Fly   984 TYARFTNKEKTSREFVAKRATLA 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14183	NP_649172.3	AAA	622..751	CDD:278434	31/158 (20%)
Pex1	NP_652016.1	PEX-1N	93..168	CDD:286361	18/90 (20%)
		SpoVK	479..974	CDD:223540	94/546 (17%)
		P-loop_NTPase	480..604	CDD:304359	13/123 (11%)
		AAA	757..887	CDD:278434	26/136 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900