Protein Alignment CG14183 and cdc-48.1

DIOPT Version :9

• Sequence 1: NP_649172.3
• Gene: CG14183 / 40192
• FlyBaseID: FBgn0036931
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: NP_496273.1
• Gene: cdc-48.1 / 174624
• WormBaseID: WBGene00007352
• Length: 809
• Species: Caenorhabditis elegans
• Alignment Length: 869
• Identity: 147/869 - (16%)
• Similarity: 305/869 - (35%)
• Gaps: 275/869 - (31%)

  Fly    86 QLKEELKDLEMSEYIYIDKALIARKLTPRDLVVWRSPQFLYRRPLDIQNIIADNRLYMND----- 145
            |.::|.|:.|:|      .|::..|:.|..|:|.:|.|       |..::||.::..|::
 Worm     8 QSEKEKKNDELS------TAILKDKVKPNRLIVDQSEQ-------DDNSVIAVSQAKMDELGLFR 59

  Fly   146 ------EEKEEKAAQDWVPISEAVKLIQA-----HERARRARVYKSNIK---------------- 183
                  :.|:.|         |:|.:|.:     :|:.|..||.::|::
 Worm    60 GDAVILKGKKRK---------ESVAIIVSDESCPNEKVRMNRVVRNNLRIRLGDVVSITPAPNLS 115

  Fly   184 ---------------------YD---KKKFLKVHQ-------------RKKINYKFT-FKPDQAM 210
                                 :|   |..||:.::             .:.:.:|.. .:|..|.
 Worm   116 YGTRIHVLPIDDTIEGLTGNLFDVFLKPYFLEAYRPLHKGDIFTVQAAMRTVEFKVVETEPAPAC 180

  Fly   211 SI-PVKRTIFSADFLKADESCENLIKKDDVADTAIDDEEALSAIQNNAACKIQSCWRGYKTRKIV 274
            .: |.....:..|.:|.:|      :::.:.|...||   |..::...|          :.:::|
 Worm   181 IVSPDTMIHYEGDPIKREE------EEESMNDIGYDD---LGGVRKQLA----------QIKEMV 226

  Fly   275 KIRKRFKE--ELYGMKKIRKL---KRPNQTANSIMEMYKNEMLKKKLDEDFINLINDERTRLLQF 334
            ::..|..:  :..|:|..|.:   ..|......|.....||      ...|..|||
 Worm   227 ELPLRHPQLFKAIGIKPPRGILLFGPPGTGKTLIARAVANE------TGSFFFLIN--------- 276

  Fly   335 RSPWMMEDIS----DHIRAWFKEFYDATGNFHPYPDPVKQGTVLVVIDETMTPMEFQESLGKKPL 395
             .|.:|..:|    .::|..|:|.             .|....::.|||.       :::..|
 Worm   277 -GPEVMSKMSGESESNLRKAFEEC-------------EKNQPAILFIDEI-------DAIAPK-- 318

  Fly   396 SKAELKKLRDKEKKEKRKKKEKLKQL--KMKEAKRRKKLRDAGVIDIGYELTASKAIENIEETMK 458
                      :||.....::..:.||  .|...|.|..|    |:     :.|:....:|:..::
 Worm   319 ----------REKTNGEVERRIVSQLLTLMDGVKGRSNL----VV-----IAATNRPNSIDGALR 364

  Fly   459 KYSKDWRNVD----------EYLNKNHDPIKEWVTEEQLAKIHQEVRGLVD------------EY 501
            ::.:..|.:|          |.| :.|....:...:..|.:|..|..|.|.            :.
 Worm   365 RFGRFDREIDIGIPDAVGRLEIL-RIHTKNMKLADDVDLEQIANECHGFVGADLASLCSEAALQQ 428

  Fly   502 MRVEYELLREALAKDNDEKYKALKVKYPKKKKEKRKKKPKDMTGDRTLESLYNELKDAGIIEEIG 566
            :|.:.||:.....:.:.|...:|.|.....:..:.|..|..:. :..:|:......|.|.::.:
 Worm   429 IREKMELIDLEDDQIDAEVLNSLAVTMENFRFAQGKSSPSALR-EAVVETPNTTWSDIGGLQNV- 491

  Fly   567 HRDFDEFITDFNFVADDTRDEDGLTTLGPAKGDIKMVIQ------ESMLGMGEFDVPKPKSLLLI 625
                                          |.:::.::|      |..|   :|.:...:.:|..
 Worm   492 ------------------------------KRELQELVQYPVEHPEKYL---KFGMQPSRGVLFY 523

  Fly   626 GPLNSGKRLLCEIIASELDAVFMNL-SPENTYKYAKDLKYFLHVILKVAKAFQPTIMYIEEAHRL 689
            ||...||.||.:.||:|..|.|::: .||....:..:.:..:..:...|:|..|.:::.:|...:
 Worm   524 GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVRDVFDKARAAAPCVLFFDELDSI 588

  Fly   690 FWKK---VPPEAVEINPRLLGTSLASKILKPLKKNDKIVLVGTSNMPWAANGGIKR--AFQKVLL 749
            ...:   ...:....:.|::...|........|||  :.::|.:|.|...:..:.|  ...:::.
 Worm   589 AKARGGGAGGDGGGASDRVINQVLTEMDGMNAKKN--VFIIGATNRPDIIDPAVLRPGRLDQLIY 651

  Fly   750 IPKCDYGTSFLLWLELMTENAPDDMKEYAYSALARVLQAYNSGD------------IDDNVKETL 802
            ||..|..:...: |:......|.. |:...:.||:....::..|            |.:::::.:
 Worm   652 IPLPDEASRHQI-LKASLRKTPLS-KDLDLTFLAKNTVGFSGADLTEICQRACKLAIRESIEKEI 714

  Fly   803 NI-----DRKMR----LKNEALDP 817
            .|     ||:.|    ::::|:||
 Worm   715 RIEKERQDRQARGEELMEDDAVDP 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14183	NP_649172.3	AAA	622..751	CDD:278434	27/134 (20%)
cdc-48.1	NP_496273.1	CDC48_N	31..112	CDD:280513	18/96 (19%)
		CDC48	52..775	CDD:273521	132/812 (16%)
		CDC48_2	137..197	CDD:215011	9/59 (15%)
		AAA	247..376	CDD:278434	32/185 (17%)
		AAA	520..654	CDD:278434	28/135 (21%)
		Vps4_C	<727..771	CDD:286426	3/12 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900