Protein Alignment kug and Fat1

DIOPT Version :10

• Sequence 1: NP_001027138.2
• Gene: kug / 40191
• FlyBaseID: FBgn0261574
• Length: 4699
• Species: Drosophila melanogaster
• Sequence 2: XP_063131847.1
• Gene: Fat1 / 83720
• RGDID: 621254
• Length: 4644
• Species: Rattus norvegicus
• Alignment Length: 4778
• Identity: 1737/4778 - (36%)
• Similarity: 2623/4778 - (54%)
• Gaps: 397/4778 - (8%)

  Fly    61 RFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRV-GLNAEVKYRIISGDKEKLFKAEEKLVGDFA 124
            :|:|..||||:.|||..|||   |.|.|..|:.: ..:.|::|:|||||.|.||||||.::|||.
  Rat    34 QFTHVQYNVTVHENSAAKTY---VGHPRKMGIYILDPSWEIRYKIISGDNENLFKAEEYVLGDFC 95

  Fly   125 FLAIRTR-TNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQY 188
            ||.|||: .|..:||||..:.|.:.:||     ...|:..|..|.:.::|||.|||.|||.||.|
  Rat    96 FLRIRTKGGNTAILNREVRDHYTLVIKA-----VEKVTDAEARAKVRVQVLDTNDLRPLFSPTSY 155

  Fly   189 TVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFE 253
            :|.:||:|....||.:|:|.|||:|.|||.|||....::.||||||:|.:.|..:|...|...:|
  Rat   156 SVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTSGVVVLTGRLDVLETQRYE 220

  Fly   254 LTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDT 318
            |.::|.|||..:...:..:|..|:::.|:|.|..||||...|.|......:| .|.|:.|.|.|.
  Rat   221 LEILAVDRGMKLYGSSGVSSLAKLTVHVEQANECAPEITAVTLSPSELDKDP-TYAIITVEDCDQ 284

  Fly   319 GINGNIGRLEIVDGNPDGTFLLKAAET------KDEYYIELNQFAHLNQQHFIYNLTLLAEDLGT 377
            |.||.|..|.||.|:     ||:..:|      ...:.::.......:...:.||||:.|:|.||
  Rat   285 GANGEIASLSIVAGD-----LLQQFKTVRSFPGSKAFKVKAVGGVDWDSHPYGYNLTVQAKDKGT 344

  Fly   378 PRRFAYKSVPIQIKPESKNIPI-FTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVG 441
            |.:|:...|...|.|:.:..|: |..::|...|.|.||.:.||:.:| :.|.......|:....|
  Rat   345 PPQFSPVKVIHVISPQFRAGPVKFEMDVYRAEISEFAPPHTPVVLVK-AIPSYSHLRYVFKSTPG 408

  Fly   442 GNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPI 506
               ..:|.:|.::|::...:.:..:..:.:.|.|:..|       :::|.||.:.|...|.|.|.
  Rat   409 ---KPKFGLNHNTGLISILEPIKRQHTTHFELEVTTSD-------RRASTKVVVKVVGTNSNPPE 463

  Fly   507 FENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDF 571
            |...:...|.:||...|:.|::::|.|.|.|||.|::|||||||.|||.||||:|.|.|:..||:
  Rat   464 FTQTSYKASFDENAPVGTPVMRVSAVDPDEGENGYVTYSIANLNHVPFVIDHFTGAVSTSENLDY 528

  Fly   572 ETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTS 636
            |.|.|.|.|.||||||||||||:.|:..:|.:.::|||.|.||:.||.|.:.:...:|.::...|
  Rat   529 ELMPRVYMLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKTNCEGTIPRDLGVGEQITTVS 593

  Fly   637 AIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKK---TTLTNRILKVSATDGTHFSDDL 698
            |||.|...::.|::..|||...|.|:|:||.||:...|..   ..::...|:::||||.:|:..|
  Rat   594 AIDADELQLVRYQIEAGNELDLFGLNPSSGVLSLKHSLMDGLGAKVSFHSLRITATDGENFATPL 658

  Fly   699 IINVHL----MPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLT 759
            .||:.:    .|.:|             .|.|||||:.|||.|..|.|.:.:..:..:|.|
  Rat   659 YINLTVAASRKPVNL-------------RCEETGVAKMLAEKLLQANKLHHQGDAEDIFFD---- 706

  Fly   760 PSRYGQNVHRPEF-VNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRID 823
              .:..|.|.|:| .:.|..:.:.|.:.:|.::.::.|.|.|.|:|||||:|||.|:.||.|.:|
  Rat   707 --SHSVNAHAPQFRGSLPTGIEVKEDLPVGASILFMNATDLDSGFNGKLVYAISGGNDDSCFTVD 769

  Fly   824 PDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTE 888
            .:.|.|:::..||||..::|.|||||||||.|.::..::|.:|:||.|||.|...:......::|
  Rat   770 METGMLKVLSPLDREVTDKYTLNITVYDLGIPQRAAWRLLDVTVLDANDNAPEFLQESYFVEVSE 834

  Fly   889 SARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAK 953
            ...|.:.:..:.|||.|.|.:..||||:..:...|.::..||.:::.:|||||.|..:.|.|.|:
  Rat   835 DKEINSEIIQVEATDKDLGPSGHVTYAILTDTEKFAIDRVTGVVKIIQPLDREVQRVHYLKIEAR 899

  Fly   954 DGGS--PVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQ 1016
            |..:  |.|||..|:.|.:||||||.|.|....|..|||||||.||::..:||.|.|:|.:::::
  Rat   900 DQATEEPWLSSTVLLKVSLDDVNDNPPRFIPPSYSVKVREDLPEGTIIMWLEAHDPDVGQSSQVR 964

  Fly  1017 FSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDP-SLTSDMSIVIMIIDVN 1080
            :||.:  ..|..|.:||.:||:|....||:|.||::||.|.|.|.|.| ||:|...:.:.::|||
  Rat   965 YSLLD--HGEGHFDVDKLSGAVRIVQQLDFEKKQLYNLTVRAKDKGKPASLSSTGYVEVEVVDVN 1027

  Fly  1081 ENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQ-GS 1144
            ||..||.|..||.:|.|||:.|.|:.||.|:|.|.|| ..:.:|.|||..|.|:|:|.:::: |.
  Rat  1028 ENLHAPVFSSFVEKGTVKEDVPMGSSVMTVSAHDEDT-GRDGEIRYSIRDGSGVGVFRIDEETGV 1091

  Fly  1145 ITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVEN 1209
            |.:..:||.|:.:.||||:.|.|..:||||:.:||||:||:.|||.|.|.:||||..:.|.|.::
  Rat  1092 IETSDRLDRESTSHYWLTVYATDQGVVPLSSFIEVYIEVEDVNDNAPQTSEPVYYPEIMENSPKD 1156

  Fly  1210 VEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDN 1274
            |.::.::|||||...:..:||.|.|||..|:|.|..|||:|.||.||||||.|.||||||.::||
  Rat  1157 VSVVQIEAFDPDSSSSDKLTYRITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDN 1221

  Fly  1275 GSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVP-------SSATVNQSIFQVHAIDSDSGENG 1332
            |.|..|:.:|::|.:||.|||.|:|.|:.||:::|       ..:...:.:::|.|.|.|.|.|.
  Rat  1222 GVPPRSTIARVIVKILDENDNRPQFLQKFYKIRLPEREKADGDRSAKREPLYRVIAADKDEGPNA 1286

  Fly  1333 RITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEI-HIKAEDNGIPKKSQTARVNIVVVPVN 1396
            .::|||:.|....:|.|:.:.|.:. :|...:..|::| .|||.|||.|:||.|.|::|..:. .
  Rat  1287 ELSYSIEEGNEHGRFSIEPKTGVVS-SKKFSAAGEYDILSIKAIDNGRPQKSSTTRLHIEWIS-K 1349

  Fly  1397 PNSQNAPLIVRKTSENVVDLT--ENDKPGFLVTQILAVDDDNDQLWYNI---------------- 1443
            |.....|:   ...|:|...|  |:|....:: .:::|:.....||::|
  Rat  1350 PKPSLEPI---SFEESVFSFTVMESDPVAHMI-GVISVEPPGMPLWFDIIGDALAREAFYIFQMT 1410

  Fly  1444 -------SNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDIND 1501
                   ..||.|:.|.:.:..|.|:::|.||.|.:.|||||:..||||.|..|.:|::|||.||
  Rat  1411 CDLNCTAEGGNYDSHFDVDKGTGTIIVAKPLDAEQKSSYNLTVEATDGTSTILTQVLIKVIDTND 1475

  Fly  1502 NPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIV 1566
            :.|||:...|.|::.|:.|.|:.|:|:.|.||||..||.|.|.::.||:||..||:|..:|.:..
  Rat  1476 HRPQFSTSKYEVSVPEDTEPETEILQISAVDRDEKNKLIYTLQSSIDPASLKKFRLDPATGALYT 1540

  Fly  1567 TQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKL 1631
            :::||.|...||:|.|.|:||..|.|||:|:|||||.|.|||.|.||:...:.:|.||||:||.:
  Rat  1541 SEKLDHEAIHQHVLTVMVRDQDVPVKRNFARIIVNVSDMNDHSPWFTSSSYEGRVYESAAVGSVV 1605

  Fly  1632 AEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPP 1696
            .:|.|:|||.|.|||:.|||.:||:|:.|.|||..|.|..|..|:.:...:|.|.|||.|.|.||
  Rat  1606 LQVTALDRDKGRNAEVLYSIESGNIGNSFTIDPILGSIKTARELDRSHQVDYDLMVKATDKGEPP 1670

  Fly  1697 LSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFNIISGNINESFR 1761
            :|....|.|.||:::|..|||.:...:.||.|.:.||:||..|:|.|.||:.:.:..|||.::|.
  Rat  1671 MSEMTSVRISVTVADNASPKFTSKEYSAEISEAIRIGSFVGMVSAHSQSSVMYEVKDGNIGDAFN 1735

  Fly  1762 INPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPE 1826
            |||.:|.||....:|:|::.::.|||:|||||..|:...:::||.|.|||.|.|.:.||.|.:.|
  Rat  1736 INPHSGSIVTQRALDFETLPIYTLTVQGTNMAGLSTNTTVVVHIQDENDNPPAFTRAEYSGFISE 1800

  Fly  1827 SAAIGSYVLKVHDSSKD-HLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDY 1890
            ||::.|.||    :.|: .|.::..|||...|.::.|.||:....|:|.||.|||||..:..|||
  Rat  1801 SASVNSVVL----TDKNVPLVIRATDADRESNALLVYQIVEPSVHNYFAIDPTTGAIHTVLSLDY 1861

  Fly  1891 ETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVS 1955
            |....:.|.|.|.|||.|:|.:...|:||:.||::|||||||::.....:|.|||::.|.|..|:
  Rat  1862 EETRVFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFSKSLYEASLLLPTYKGVNVITVN 1926

  Fly  1956 AKDADN---DTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAIL 2017
            |.|||:   ..|.:.|..||..|.|.::..||.|..:|...|.:.    |.|.||||||.|:::.
  Rat  1927 ATDADSRAFSQLIYSITKGNIGEKFSMDHKTGTIAIQNTTQLRSR----YELTVRASDGRFTSVA 1987

  Fly  2018 IVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGIS 2082
            .|:|.|..:.:|...|.:::|.....||:|:..|:.::..|||.::|.:.||||||.:.|.|..:
  Rat  1988 SVRINVKESRESPLKFTQDAYSAVVKENSTEAKTLAVITAIGNPINEPLFYRILNPDRRFKISHT 2052

  Fly  2083 SGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYA 2147
            ||.|.|||:.||||.::.:.:.||...   :...|.|...|  :.::|.|.|||.|:|||:||||
  Rat  2053 SGVLSTTGIPFDREQQETFVVVVEVTK---EREPSAVAHVV--VKVTVEDQNDNAPVFVNLPYYA 2112

  Fly  2148 TVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKLDRKSGELSIKQHVEGH---NRNY 2209
            .|.:|...|.:|..|.|||.||..||:|.|.||: :.:.|::. .||::|:|:..| |   |:.|
  Rat  2113 VVKVDAEVGHVIRHVTAIDRDSGRNGDVHYYLKE-HHDHFEIG-PSGDISLKKQFE-HDTLNKEY 2174

  Fly  2210 ELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSL 2274
            .:||.|.||.....|:|..:.:.|::::||||||.||:..:.|:|:.:|.: |.::|.||.|..:
  Rat  2175 LVTVVAKDGGNPAFSAEVLVPITVMNKAMPVFEKAFYSAEIPENVQTHSPV-VHVQANSPEGLKV 2238

  Fly  2275 IYTISSES--QSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDC 2337
            .|:|:...  ..|.|::|||.|.|:..||:|...::.:||||||||:|.:|||.:.:.:.|:||.
  Rat  2239 FYSITDGDPFSQFTINFNTGVINVIAPLDFESHPAYKLSIRATDSLTGAHAEVFVDIVVEDINDN 2303

  Fly  2338 YPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLY 2402
            .|......|:.|:.|.:..|..||::.|||:||..|..:||.:.. |...:.:.|:||...|.:.
  Rat  2304 PPVFVQQSYSTTLSEASVIGAPILQVRATDSDSEPNRGISYQLIG-NHSKSHDHFHIDSHTGLIS 2367

  Fly  2403 LKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQF 2467
            |...|||||.:.|.::|...|.|.|.|||...|.:.|.|||||.|.|.:..|..::|..|..|.|
  Rat  2368 LVRALDYEQFQQHKLLVRAVDGGMPPLSSDVVVTVDVTDLNDNPPLFEQQVYEARISEHAAHGHF 2432

  Fly  2468 VALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHT 2532
            |...||.|.|.||.|.|||.|:.||:.:::.||..||:|:|.|....|.|....||:||||||..
  Rat  2433 VMCVKACDADRSDLDRLEYSILSGNDHKSFVIDGETGIITLSNPRRHTLKPFYSLNVSVSDGVFR 2497

  Fly  2533 AYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKK 2597
            :.||:.::::..|::||:|.|:.||.::.||......::.|||:|.|.|.|.:|.|.:|::..|.
  Rat  2498 SSARVNVTVMGGNLHSPVFHQNEYEVELAENAPLHTLVVQVKATDRDSGIYGHLTYHLVNDFAKD 2562

  Fly  2598 IFLIDQTTGVITSKVTFDREKKDEYV--VLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYK 2660
            .|.::....|.|.: ..|||...|.|  |.|...|.|||..|.::.||:.|.|||.|.|...:|:
  Rat  2563 RFYVNDGGQVFTLE-RLDREAPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRSTKYE 2626

  Fly  2661 MVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYG 2725
            :.|.::.....:::.|.|.|.|...|..|.:.|  :::.::|::.:|||:.||.|..|.......
  Rat  2627 VNVGSSAAKGTSVVKVFASDADEGSNADVTYAI--EADSESVEENLEINQLTGLITTKESLIGLE 2689

  Fly  2726 VNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGN 2790
            ...:.|||||.|.|.|...|.|||.::|:..:..:|.|.:......|.|..|.||.:..:.:..:
  Rat  2690 NEFFTFFVRAVDNGSPPKESVVPVYVKILPPEVQLPRFSEPFYTYSISEDMPIGTEIDLIRVEHS 2754

  Fly  2791 YTFKFSIA------ADQDHFMISD--SGELILQQTLDREQQESHNLIVVAETSTVPVF--FAYAD 2845
            .|..:::.      :::|.|.:.|  ||.|.|:::||.|..:.:...::|. .|:..:  .|..|
  Rat  2755 GTVLYTLVKGNTPESNRDEFFVIDRQSGRLKLEKSLDHETTKWYQFSILAR-CTLDDYEVVASID 2818

  Fly  2846 VLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYL-ESDTENIQNI 2909
            |.|.|:|.|||.|..::..|.|.:.||......:::|.|:|.|:|.||.:.|.| :|...:|...
  Rat  2819 VSIQVKDANDNSPVLESNPYEAFIVENLPAGSRVIQVRASDLDSGVNGQVMYSLDQSQDADIIES 2883

  Fly  2910 FDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHP-KHDAKVPVTIKIVDYNDNAPVFKLPIEG 2973
            |.|::.:||||.|..||.|.::.|..||:|:|:|.. :..:...|.:.:.|.||:.|.|...|..
  Rat  2884 FAINMETGWITTLKELDHEERASYQIKVVASDHGEKVQLSSTAIVDVTVTDVNDSPPRFTAEIYK 2948

  Fly  2974 LSVFENALPGTVLINLLLIDPDIEK--QEMDFFIVSGDKQAQFQI---GKSGELFIAKPLDREQL 3033
            .:|.|:..||.|:..|...|.|.|:  :::.:||..||...||.:   .....:::.|||||||.
  Rat  2949 GTVSEDDPPGGVIAILSTTDADSEEINRQVSYFITGGDALGQFAVENMQNDWRVYVKKPLDREQK 3013

  Fly  3034 MFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQS 3098
            ..|.|::.||||.|::||.||:.|.|.|||:|.|.:..|..:..|....|..:::|.|.|.|.:|
  Rat  3014 DSYLLTVTATDGTFSSKARVEVKVLDANDNSPVCERTAYSDAIPEDALPGKLVMQVSATDADIRS 3078

  Fly  3099 --KLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVND 3161
              ::.:.|.|.||:.|.:..::|.|:..:.||||....|.|:....||..  :.|.:.|::|:.|
  Rat  3079 NAEITYTLFGSGAEKFKLNPDTGELRTLALLDREEQAVYHLLVKATDGGG--RSCQATIVLTLED 3141

  Fly  3162 INDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIR 3226
            :|||.|.|:...|.::|.|:.:..|.:|:|.|.|.|.|:||:|.|||:......|.|::.:||::
  Rat  3142 VNDNTPEFTADPYAITVFENTEPGTPLTRVQATDADAGLNRKISYSLLDSADGQFSINEQSGILQ 3206

  Fly  3227 LHKSLDRETISLFNLTVKAEDCGVP-KLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGT 3290
            |.|.||||..:::.||:||.|.|:| ||.:..||.|::||||||||.|..|:|...:.|:...||
  Rat  3207 LEKHLDRELQAVYTLTLKAADQGLPRKLTATGTVVVSVLDINDNPPVFEYREYGATVSEDIVIGT 3271

  Fly  3291 EVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGT 3355
            ||.:|||.|.||..||:|.|.|:||||.|||.:||.||.:.:...||||.|..|:||::|.||||
  Rat  3272 EVLQVYAASRDIEANAEITYAIISGNEHGKFSIDSKTGAIFIIENLDYESSHGYYLTVEATDGGT 3336

  Fly  3356 PPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERG 3420
            |.||:.|.|||:|.|||||||.|.|:.|...|:||..:...::.:.|.|.|...|..:.|:|..|
  Rat  3337 PSLSDVATVNINITDINDNSPVFSQDSYTTVVSEDAALEQPVITIMADDADGPSNSHILYSIIEG 3401

  Fly  3421 DNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSS 3485
            :....|:|||..|.|.|::||||||||.|||.:||.|.|:|.|.|:..:||::.|.|||||:||.
  Rat  3402 NQGSPFTIDPVRGEIKVTKPLDRETISGYTLTVQAADNGNPPRVNTTTVNIDVSDVNDNAPLFSR 3466

  Fly  3486 SNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNL 3550
            .||||::|||:.:|:..|...::|.|.:.|..|::|.|.|||:..:|.:.|.|.|.||:.....:
  Rat  3467 DNYSVIIQENKPVGFSVLKLVVTDKDSSHNGPPFSFAIVSGNDDNMFEVNQHGVLLTAATVKRKV 3531

  Fly  3551 QDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQ 3615
            :|.:::.|:|.|||.|.|.|...:.:::||||.:||.:.|||:.|.:..:::||..|||:||:||
  Rat  3532 KDHYLLHVKVADNGKPQLSSLTHIDIRVIEESIHPPAILPLEIFITASGEEYSGGVIGKIHATDQ 3596

  Fly  3616 DKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDGKFHVFSIVKINV 3680
            |.||.|.:||....|.      ||::|:..||:.|...||||.|.|||||:||||...:.:.:::
  Rat  3597 DVYDTLTYSLDPHMDG------LFSVSSTGGKLIAHRKLDIGQYLLNVSVTDGKFTTVADITVHI 3655

  Fly  3681 ELVTNDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHAVG 3745
            :.||.:||..::.|||..::..||:..:.:.|.|::|||:..|:.|:.:::|    |.:..|
  Rat  3656 QQVTQEMLNHTIAIRFANLTPEEFVGDYWRNFQRALRNILGIRKNDIQIVSL----QPSEPH--- 3713

  Fly  3746 NRRARSIDSDLNVVFAVRKQ---QIIPDSDEFFTSDEIRQTLIDKKNEIENETNLVVEDVLPSTC 3807
                    |.|:|:..|.|.   ||        ::.::...:.....:||....:.:.||....|
  Rat  3714 --------SHLDVLLFVEKSGGTQI--------STKQLLHKINSSVTDIEEIIGVRILDVFQKLC 3762

  Fly  3808 QSNKNDCVHGECKQILQILKNNVTTTFTDVISFAAPSYIPVNTCVCRPGFDGKHCKETVNACSTD 3872
            ..  .||....|.:.:.:.:|.::|..|..:||..|.:.....|:|:.|    .|......|..:
  Rat  3763 AG--LDCPWKFCDEKVSVDENIMSTHSTARLSFVTPRHHRTAVCLCKDG----TCPPVHQGCEDN 3821

  Fly  3873 PCSPQRICMPSGSALGYQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAHYKI--- 3934
            ||.....|:.......|.||||.|        ..:||...|       :::|.|.|:..|::
  Rat  3822 PCPAGSECVADPREEKYSCVCPGG--------GFAKCPGSS-------SITFTGSSFVKYRLMEN 3871

  Fly  3935 -NKVKAKFTLENGFSYSLQIRTVQQTGTLLYASGKVDYNILEIINGAVQYRFDLGSGEGVISVSS 3998
             |:::.|.|        :::||......::||.| .||:||||..|.:||:||.|||.|::||.|
  Rat  3872 ENRLEMKLT--------MRLRTYSSHAVVMYARG-TDYSILEIHTGRLQYKFDCGSGPGIVSVQS 3927

  Fly  3999 INISDGEWHQISLERSLNSAKVMVDNKHVSHGSAPGVNGILNIQSNDIFVGAEVRPHPSIIGYE- 4062
            |.::||:||.:|||...|.||:::|..|.:.|:|||....||:.:..|| |..:|...:..|..
  Rat  3928 IQVNDGQWHAVSLEVEGNYAKLVLDEVHTASGTAPGALKTLNLDNYVIF-GGHLRQQGTKHGRNT 3991

  Fly  4063 DIQRGFIGCMANIKIAKESLPLYISGGSTIAALKRFTNVEFKCDPSNVLVRLGICGSQPCANSGI 4127
            .:..||.|||.:|.:..:.|||. :.....|.::.:.::...|    :|.....|.|.||.|.|:
  Rat  3992 QVANGFRGCMDSIYLNGQELPLN-NKPRAYAHIEEWVDLAHGC----LLTATEDCSSNPCQNGGV 4051

  Fly  4128 CKELDTDVFECACQPRYSGKHCEIDLDPCSSGPCLFGGRC--DYHGPNNYSCTCPIHLSGKRCEY 4190
            |....|..:.|.|...::|.:||:.::||||.|||:||.|  |..|   :.|.|....:|:||:.
  Rat  4052 CNPSPTGGYYCKCSALHAGTYCEVSVNPCSSNPCLYGGTCMVDNGG---FVCQCRGLYTGQRCQL 4113

  Fly  4191 GKFCTPNPCKNGGICEEG-DGISHCMC-RGYTGPTCEIDVDECENQPCGNGATCINEPGSFRCIC 4253
            ..:|...||||||.|.:. || :.|.| .|:.|..|:.|:|||...||.|||.|.|..||:.|.|
  Rat  4114 SPYCKDEPCKNGGTCFDSLDG-AVCQCDSGFRGERCQSDIDECAGNPCRNGALCENTHGSYHCNC 4177

  Fly  4254 PSYLTGASCGDPLYSNSISTKLKNFSIEHISGIISGVA-VVLVIISCVLCCVVLKRSSSSKRRNR 4317
            .....|..|.|...::.:||.. |..:....|||..:| :.|:::..|||    ::..|.|::::
  Rat  4178 SQEYRGKHCEDATPNHYVSTPW-NIGLAEGIGIIVFIAGIFLLVVVFVLC----RKMISRKKKHQ 4237

  Fly  4318 LEKDKNKSSYKEANL-----NSLVDKDNYCKPNVKLSNL--EVNQRPISYT-AVPNDNLVLSNRN 4374
            .|.:..:.....|.|     :|...|:.|       |::  :|..|||||| ::|:|:.
  Rat  4238 AEPEDKRLGPTTAFLQRPYFDSKPSKNIY-------SDIPPQVPVRPISYTPSIPSDSR------ 4289

  Fly  4375 FVNNLDILRSYGSA-GDELENVPFEYQKVNRNKQHVNINSC-----------HSTDADNAYKQEW 4427
              ||||.....||| .:..|...|..:.::.:::.|.:.|.           ..:|:|:..|..|
  Rat  4290 --NNLDRNSFEGSAIPEHPEFSTFNPESMHGHRKAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSW 4352

  Fly  4428 CEQMHLRTFSENKLNNELKRDFGPSVSRFSTGKLIQVEMPNVCHSSS----ANFVDYSALANG-- 4486
            ......:....:...::...:..||....:...|.:|:..:...|.|    |:.|..:.|.|.
  Rat  4353 DFDYDAKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDNASIVTVTHLVNAVV 4417

  Fly  4487 ------------------QYHWDCSDWVRKSHNPLPDITEVPGAEIADS-SSLHSNDSNESKS-- 4530
                              .||||.|||:...  |||||.|.|..|:.|. :.|:|.|.|...:
  Rat  4418 DTVNKEESLAAPDLSKPRGYHWDTSDWMPSV--PLPDIQEFPNYEVIDEHTPLYSADPNAIDTDY 4480

  Fly  4531 -------KKAFFVHRED------------------GDVDPTRDIAALNEDIGS-----------E 4559
                   :..|....||                  ..:.|.||:.|.. .:||           :
  Rat  4481 YPGGYDIESDFPPPPEDFPAPDELPPLPPEFSDQFESIHPPRDMPAAG-SLGSSSRNRQRFNLNQ 4544

  Fly  4560 YLDS---------------EAESCLEP-----------FMLPRSSNQPL---------SRLSSFN 4589
            ||.:               |..:|.||           |..|...|.|:         |.:|:..
  Rat  4545 YLPNFYPVDMSEPQKQGAGENSTCREPYTPYPPGYQRNFEAPTIENMPMSVYTSTASCSDVSACC 4609

  Fly  4590 NIENE----DYKSN--------TVPLPSKVSHS 4610
            .:|:|    ||:|.        |:|......|:
  Rat  4610 EVESEVMMSDYESGDDGHFEEVTIPPLDSQQHT 4642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kug	NP_001027138.2	Cadherin_repeat	66..178	CDD:206637	50/113 (44%)
		Cadherin_repeat	187..285	CDD:206637	39/97 (40%)
		Cadherin_repeat	404..503	CDD:206637	22/98 (22%)
		Cadherin_repeat	513..609	CDD:206637	51/95 (54%)
		Cadherin_repeat	622..708	CDD:206637	28/92 (30%)
		Cadherin_repeat	776..873	CDD:206637	42/96 (44%)
		Cadherin_repeat	883..976	CDD:206637	34/94 (36%)
		Cadherin_repeat	984..1082	CDD:206637	42/98 (43%)
		Cadherin_repeat	1092..1189	CDD:206637	44/97 (45%)
		Cadherin_repeat	1197..1295	CDD:206637	49/97 (51%)
		Cadherin_repeat	1303..1386	CDD:206637	28/90 (31%)
		Cadherin_repeat	1413..1502	CDD:206637	34/113 (30%)
		Cadherin_repeat	1510..1608	CDD:206637	46/97 (47%)
		Cadherin_repeat	1621..1713	CDD:206637	44/91 (48%)
		Cadherin_repeat	1724..1811	CDD:206637	37/86 (43%)
		Cadherin_repeat	1819..1927	CDD:206637	44/108 (41%)
		Cadherin_repeat	1948..2030	CDD:206637	30/84 (36%)
		Cadherin_repeat	2037..2136	CDD:206637	35/98 (36%)
		Cadherin_repeat	2144..2235	CDD:206637	37/93 (40%)
		Cadherin_repeat	2246..2336	CDD:206637	34/91 (37%)
		Cadherin_repeat	2345..2445	CDD:206637	38/99 (38%)
		Cadherin_repeat	2453..2545	CDD:206637	38/91 (42%)
		Cadherin_repeat	2555..>2633	CDD:206637	26/79 (33%)
		Cadherin_repeat	2658..2759	CDD:206637	30/100 (30%)
		Cadherin_repeat	2774..2856	CDD:206637	24/91 (26%)
		Cadherin_repeat	2865..2963	CDD:206637	34/99 (34%)
		Cadherin_repeat	2974..3063	CDD:206637	36/93 (39%)
		Cadherin_repeat	3072..3165	CDD:206637	28/94 (30%)
		Cadherin_repeat	3173..3269	CDD:206637	42/96 (44%)
		Cadherin_repeat	3277..3374	CDD:206637	52/96 (54%)
		Cadherin_repeat	3383..3479	CDD:206637	40/95 (42%)
		Cadherin_repeat	3488..3579	CDD:206637	32/90 (36%)
		Cadherin_repeat	3590..3681	CDD:206637	40/90 (44%)
		EGF_CA	3866..3903	CDD:238011	10/36 (28%)
		Laminin_G_2	3953..4077	CDD:460494	53/124 (43%)
		EGF_CA	<4121..4150	CDD:238011	9/28 (32%)
		EGF_CA	4152..4189	CDD:238011	16/38 (42%)
		EGF_CA	4195..4225	CDD:238011	13/31 (42%)
		EGF_CA	4227..4262	CDD:214542	16/34 (47%)
Fat1	XP_063131847.1	None