DRSC/TRiP Functional Genomics Resources

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Protein Alignment kug and Pcdhb9

DIOPT Version :10

Sequence 1:NP_001027138.2 Gene:kug / 40191 FlyBaseID:FBgn0261574 Length:4699 Species:Drosophila melanogaster
Sequence 2:NP_001102860.1 Gene:Pcdhb9 / 680047 RGDID:1596840 Length:798 Species:Rattus norvegicus


Alignment Length:810 Identity:213/810 - (26%)
Similarity:337/810 - (41%) Gaps:168/810 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   780 SINESVQLGETVAWIEAKDRDLGYNGKLVF----AISDGDYDSVFRIDPDRGELQIIGYLDRER- 839
            ||.|..:.|..||.: |||..|| .|:|..    .:|| ||.....:||:.|:|.:...||||. 
  Rat    39 SILEETESGSFVAHL-AKDLGLG-AGELAARSARVVSD-DYKQRLLLDPETGDLILREKLDREEL 100

  Fly   840 ---QNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHA 901
               .:..||...| .|..|.:.....|  .|.|:||:.|.........::.|:::.||......|
  Rat   101 CGSLDPCVLPFQV-SLEKPVQYFQGEL--LIQDINDHAPEFPDRELLLKIPENSQPGTRFSLKLA 162

  Fly   902 TDADSGINAQVTYALSV--ECSDFTVNATTGC----LRLNKPLDREKQDNYALHITAKDGGSPVL 960
            .|.|.|.|....|.:|.  .....|.|.:.|.    |..::.||||:|...:|.:.|.|||||..
  Rat   163 QDLDVGNNGLQEYRVSTNPHFHVLTRNNSEGKKYPELVQDRALDREEQAELSLTLIALDGGSPPR 227

  Fly   961 SSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQD 1025
            |..|||.:|:.|:|||||.|....|..:|.|..|..:.:..:.|.|.|.|....:.:.|.:.:.:
  Rat   228 SGTALVRILIIDINDNAPEFVNSPYEVQVLESCPPDSPILTVLARDADAGNFGSVSYGLFQASDE 292

  Fly  1026 -EELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFD 1089
             ::.|.|::.||.:|.:..||:|..:.:::.:.|.|||  .|:...|::|.::|||:|  |||..
  Rat   293 IQQTFSINETTGDMRLKKKLDFEKIKSYHVEIEATDGG--GLSGRGSVMIEVLDVNDN--APELT 353

  Fly  1090 DFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQLDAE 1154
            .......|.||.|             :|:               :.||.|.|:.|..:...:   
  Rat   354 ISSLTSSVPENAP-------------ETI---------------ISIFRVGDRDSGENGKAV--- 387

  Fly  1155 TKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFD 1219
                         |:|                ::|:|...|.                 |.|.| 
  Rat   388 -------------CSI----------------SENLPFILKS-----------------TFKNF- 405

  Fly  1220 PDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSR 1284
                      |.:|                   ||..||||::||:.:.:::||.|:|.|::...
  Rat   406 ----------YTLV-------------------TESPLDRESRAEYNITISVSDLGTPRLTTQHT 441

  Fly  1285 IVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGK----- 1344
            |.|.|.|||||:|.|.|..|.:.|..:.:....|..:.|.|:|||.|..||||:...:..     
  Rat   442 ITVQVSDINDNAPAFTQTSYTMFVRENNSPALHIGTISATDADSGSNAHITYSLLPPQNPQLALV 506

  Fly  1345 NKFRIDSQRGHIHIAKPLDSD--NEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVR 1407
            :...|::..|.:...:.||.:  ..||.::.|.|.|.|..|..|.|:::|:..|   .|||.::.
  Rat   507 SLISINADNGQLFALRALDYEALQAFEFYVGATDQGSPALSSQALVHVMVLDDN---DNAPFVLY 568

  Fly  1408 KTSENVVDLTE----NDKPGFLVTQILAVDDDNDQ---LWYNISNGNDDNTFYIGQDNGNILLSK 1465
            .........||    ..:||:|:|:::|||.|:.|   |.:.:....:...|.:...||.:..::
  Rat   569 PLQNASAPCTELLPRAAEPGYLITKVVAVDCDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTTR 633

  Fly  1466 YLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIM---Q 1527
            .|.......:.|.:.|.|                |.:|.:.|....||.:.:...:..:.:   .
  Rat   634 LLSERDVPKHRLLLLVKD----------------NGDPARSATVTLHVLLVDGFSQPYLPLPEVA 682

  Fly  1528 LHATDRDEDKKLFYHLHATQDPSSLALFRI 1557
            .:|...|:|....|.:.|....|||.|..:
  Rat   683 RNAVQEDDDALTLYLVIALASVSSLFLLSV 712

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kugNP_001027138.2 Cadherin_repeat 66..178 CDD:206637
Cadherin_repeat 187..285 CDD:206637
Cadherin_repeat 404..503 CDD:206637
Cadherin_repeat 513..609 CDD:206637
Cadherin_repeat 622..708 CDD:206637
Cadherin_repeat 776..873 CDD:206637 34/100 (34%)
Cadherin_repeat 883..976 CDD:206637 33/98 (34%)
Cadherin_repeat 984..1082 CDD:206637 27/98 (28%)
Cadherin_repeat 1092..1189 CDD:206637 12/96 (13%)
Cadherin_repeat 1197..1295 CDD:206637 24/97 (25%)
Cadherin_repeat 1303..1386 CDD:206637 24/89 (27%)
Cadherin_repeat 1413..1502 CDD:206637 20/95 (21%)
Cadherin_repeat 1510..1608 CDD:206637 11/51 (22%)
Cadherin_repeat 1621..1713 CDD:206637
Cadherin_repeat 1724..1811 CDD:206637
Cadherin_repeat 1819..1927 CDD:206637
Cadherin_repeat 1948..2030 CDD:206637
Cadherin_repeat 2037..2136 CDD:206637
Cadherin_repeat 2144..2235 CDD:206637
Cadherin_repeat 2246..2336 CDD:206637
Cadherin_repeat 2345..2445 CDD:206637
Cadherin_repeat 2453..2545 CDD:206637
Cadherin_repeat 2555..>2633 CDD:206637
Cadherin_repeat 2658..2759 CDD:206637
Cadherin_repeat 2774..2856 CDD:206637
Cadherin_repeat 2865..2963 CDD:206637
Cadherin_repeat 2974..3063 CDD:206637
Cadherin_repeat 3072..3165 CDD:206637
Cadherin_repeat 3173..3269 CDD:206637
Cadherin_repeat 3277..3374 CDD:206637
Cadherin_repeat 3383..3479 CDD:206637
Cadherin_repeat 3488..3579 CDD:206637
Cadherin_repeat 3590..3681 CDD:206637
EGF_CA 3866..3903 CDD:238011
Laminin_G_2 3953..4077 CDD:460494
EGF_CA <4121..4150 CDD:238011
EGF_CA 4152..4189 CDD:238011
EGF_CA 4195..4225 CDD:238011
EGF_CA 4227..4262 CDD:214542
Pcdhb9NP_001102860.1 Cadherin_2 37..117 CDD:462413 29/81 (36%)
Cadherin_repeat 145..243 CDD:206637 33/97 (34%)
Cadherin_repeat 251..348 CDD:206637 27/98 (28%)
Cadherin_repeat 360..452 CDD:206637 39/198 (20%)
Cadherin_repeat 460..562 CDD:206637 28/104 (27%)
Cadherin_repeat 581..669 CDD:206637 22/103 (21%)
Cadherin_C_2 693..775 CDD:465139 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

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