Sequence 1: | NP_001027138.2 | Gene: | kug / 40191 | FlyBaseID: | FBgn0261574 | Length: | 4699 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_071407.4 | Gene: | CDH23 / 64072 | HGNCID: | 13733 | Length: | 3354 | Species: | Homo sapiens |
Alignment Length: | 3608 | Identity: | 955/3608 - (26%) |
---|---|---|---|
Similarity: | 1496/3608 - (41%) | Gaps: | 781/3608 - (21%) |
- Green bases have known domain annotations that are detailed below.
Fly 397 IPIFTQEIYE--VSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDE----FRINPDSG 455
Fly 456 MLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENN 520
Fly 521 LAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRNYELIIRAS 585
Fly 586 DWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDI--ISY 648
Fly 649 RLSDGNEDGCFNLDPTSGSLSISCDL-KKTTLTNR--ILKVSATDGTHFSDDLIINVHLMPEDLG 710
Fly 711 GDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNF 775
Fly 776 PQELSINESVQLGETV-AWIEA--KDRDLGYNGKL-VFAISDGDYDSVFRIDPDRGE----LQII 832
Fly 833 GYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVH 897
Fly 898 CLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSS 962
Fly 963 EALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEE 1027
Fly 1028 LFRIDKHT--GAIRTQGYLDYENKQVHN----LIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAP 1086
Fly 1087 EFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSK------ITYSITGGDGLGIFAVNDQ-GS 1144
Fly 1145 ITSLSQLDAETKNFYWLTLCAQDCAI--VPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASV 1207
Fly 1208 ENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILE---- 1268
Fly 1269 --VAISDNGSPVLSSTS--RIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSG 1329
Fly 1330 ENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDN--EFEIHIKAEDNGIPKKSQTARVNIVV 1392
Fly 1393 VPVNPNSQN-APLIVRKTSENVVDLTENDKPGFLVTQILAVDDD---NDQLWYNISNGNDDNTFY 1453
Fly 1454 IGQDNGNILLSKYLDYETQQSYNLTISVTD---------GTFTAFTNLLVQVIDINDNPPQFAKD 1509
Fly 1510 VYHVNISENIEEESVIMQLHATDRDEDK--KLFYH-LHATQDPSSLALFRIDSISGNVIVTQR-L 1570
Fly 1571 DFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFT-AKIIQSKVPESAAIGSKLAEV 1634
Fly 1635 RAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSS 1699
Fly 1700 QIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSI------FFNIISGNINE 1758
Fly 1759 SFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAE-SSCQNIIIHILDANDNIPYF-VQNEYV 1821
Fly 1822 GALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTT---GAIE 1883
Fly 1884 LLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNER-ELNVTLFLPTFE 1947
Fly 1948 NV----FVRQVSAKDAD---NDTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALH 2005
Fly 2006 VRASDGIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRI 2070
Fly 2071 LNPTQLFDIGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVND 2135
Fly 2136 NCPLFVNMPYYATVSIDDPK--GTIIMQVKAIDLDSAENGEVRYELKKGN-GELFKLDRKSGELS 2197
Fly 2198 IKQHVEGHNRNYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSV 2262
Fly 2263 SIEAESPLGRSLIYTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVL 2327
Fly 2328 SVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELF 2392
Fly 2393 YIDVTDGNLYLK--TPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYF 2455
Fly 2456 TKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSST 2520
Fly 2521 VLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYAN 2585
Fly 2586 LYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGG-----GKFGFASLKVIVV 2645
Fly 2646 DVNDNVPYFLLKEYKMVVSTTVEA-------NQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVK 2703
Fly 2704 DVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSV 2768
Fly 2769 LLKIIESTPPGTVLTKLHMIGNYTFKFSIAADQDHFMISDSGELILQQTLDREQQESHNLIVVAE 2833
Fly 2834 TSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYY 2898
Fly 2899 LESDTENIQNIFDIDIYSGWITL-LTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYND 2962
Fly 2963 NAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVS-----------GDKQAQFQI 3016
Fly 3017 G-KSGELFIAKPLDREQLMFYNLSIIATDGK--------FTAKANVEIDVKDINDNTPYCLKP-- 3070
Fly 3071 -RYHIS-TNESISIGTTLVEVKAIDFDFQSKLRFYLSGKG-------------------ADDFSI 3114
Fly 3115 GKESGILKVAS-ALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSV 3178
Fly 3179 PEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRETISLFNLTV 3243
Fly 3244 KAE----DCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGV 3304
Fly 3305 NADIHYFIMSGNEQGKFKMDSTTGDLVLNATL-DYEMSKFYFLTIQAIDGGTPPLSNNAYVNISI 3368
Fly 3369 LDINDNSPTFLQ--NLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIER--GDNIGQ-FSI 3428
Fly 3429 DPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSV-PININILDTNDNAPIF-----SSSN 3487
Fly 3488 YSVVL-----QENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFN 3547
Fly 3548 HNLQDEFVIQVRVFDN--GTPP--------LYSDAWV-VVKIIEE--SQYPPIVTPLEVTINSFE 3599
Fly 3600 DDFSGAFIGKVHASDQD--KYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLD--IGLYK 3660
Fly 3661 LNVSVSDGKFHVFSIVKINVELVTNDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQK 3725
Fly 3726 DVILITLQSD----YQKASQHAVGNRRARSIDSDLNVVFAVRKQ-------------QIIPDSDE 3773
Fly 3774 FFTSDEIRQTLIDKKNEIEN-ETNLVVEDVLPS 3805 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
kug | NP_001027138.2 | Cadherin_repeat | 66..178 | CDD:206637 | |
Cadherin_repeat | 187..285 | CDD:206637 | |||
E_set | 309..390 | CDD:298831 | |||
Cadherin_repeat | 404..503 | CDD:206637 | 32/104 (31%) | ||
Cadherin_repeat | 513..609 | CDD:206637 | 28/95 (29%) | ||
Cadherin_repeat | 622..708 | CDD:206637 | 29/90 (32%) | ||
Cadherin_repeat | 776..873 | CDD:206637 | 20/104 (19%) | ||
Cadherin_repeat | 883..976 | CDD:206637 | 31/92 (34%) | ||
Cadherin_repeat | 984..1082 | CDD:206637 | 35/103 (34%) | ||
Cadherin_repeat | 1092..1189 | CDD:206637 | 32/105 (30%) | ||
Cadherin_repeat | 1197..1295 | CDD:206637 | 37/105 (35%) | ||
Cadherin_repeat | 1303..1386 | CDD:206637 | 27/84 (32%) | ||
Cadherin_repeat | 1413..1502 | CDD:206637 | 30/100 (30%) | ||
Cadherin_repeat | 1510..1608 | CDD:206637 | 33/101 (33%) | ||
Cadherin_repeat | 1621..1713 | CDD:206637 | 30/91 (33%) | ||
Cadherin_repeat | 1724..1811 | CDD:206637 | 28/93 (30%) | ||
Cadherin_repeat | 1819..1927 | CDD:206637 | 28/110 (25%) | ||
Cadherin_repeat | 1948..2030 | CDD:206637 | 20/88 (23%) | ||
Cadherin_repeat | 2037..2136 | CDD:206637 | 9/98 (9%) | ||
Cadherin_repeat | 2144..2235 | CDD:206637 | 20/93 (22%) | ||
Cadherin_repeat | 2246..2336 | CDD:206637 | 12/89 (13%) | ||
Cadherin_repeat | 2345..2445 | CDD:206637 | 30/101 (30%) | ||
Cadherin_repeat | 2453..2545 | CDD:206637 | 5/91 (5%) | ||
Cadherin_repeat | 2555..>2633 | CDD:206637 | 23/82 (28%) | ||
Cadherin_repeat | 2658..2759 | CDD:206637 | 22/107 (21%) | ||
Cadherin_repeat | 2774..2856 | CDD:206637 | 12/81 (15%) | ||
Cadherin_repeat | 2865..2963 | CDD:206637 | 33/98 (34%) | ||
Cadherin_repeat | 2974..3063 | CDD:206637 | 25/108 (23%) | ||
Cadherin_repeat | 3072..3165 | CDD:206637 | 23/113 (20%) | ||
Cadherin_repeat | 3173..3269 | CDD:206637 | 34/99 (34%) | ||
Cadherin_repeat | 3277..3374 | CDD:206637 | 31/97 (32%) | ||
Cadherin_repeat | 3383..3479 | CDD:206637 | 31/99 (31%) | ||
Cadherin_repeat | 3488..3579 | CDD:206637 | 31/106 (29%) | ||
Cadherin_repeat | 3590..3681 | CDD:206637 | 18/94 (19%) | ||
EGF_CA | 3866..3903 | CDD:238011 | |||
Laminin_G_2 | 3953..4077 | CDD:280389 | |||
EGF_CA | <4121..4150 | CDD:238011 | |||
EGF_CA | 4152..4189 | CDD:238011 | |||
EGF_CA | 4195..4225 | CDD:238011 | |||
EGF_CA | 4227..4262 | CDD:214542 | |||
CDH23 | NP_071407.4 | Cadherin_repeat | 42..128 | CDD:206637 | 32/97 (33%) |
Cadherin_repeat | 136..231 | CDD:206637 | 28/96 (29%) | ||
Cadherin_repeat | 240..344 | CDD:206637 | 33/155 (21%) | ||
Cadherin_repeat | 352..456 | CDD:206637 | 20/104 (19%) | ||
Cadherin_repeat | 465..557 | CDD:206637 | 31/93 (33%) | ||
Cadherin_repeat | 566..667 | CDD:206637 | 35/102 (34%) | ||
Cadherin_repeat | 676..774 | CDD:206637 | 32/104 (31%) | ||
Cadherin_repeat | 782..886 | CDD:206637 | 37/105 (35%) | ||
Cadherin_repeat | 894..990 | CDD:206637 | 31/95 (33%) | ||
Cadherin_repeat | 999..1098 | CDD:206637 | 30/108 (28%) | ||
Cadherin_repeat | 1106..1203 | CDD:206637 | 32/100 (32%) | ||
Cadherin_repeat | 1218..1308 | CDD:206637 | 30/90 (33%) | ||
Cadherin_repeat | 1317..1414 | CDD:206637 | 28/96 (29%) | ||
Cadherin_repeat | 1426..1523 | CDD:206637 | 29/108 (27%) | ||
Cadherin_repeat | 1533..1630 | CDD:206637 | 33/205 (16%) | ||
Cadherin_repeat | 1638..1740 | CDD:206637 | 32/194 (16%) | ||
Cadherin_repeat | 1752..1847 | CDD:206637 | 30/97 (31%) | ||
Cadherin_repeat | 1855..1955 | CDD:206637 | 33/183 (18%) | ||
Cadherin_repeat | 1963..2065 | CDD:206637 | 35/204 (17%) | ||
Cadherin_repeat | 2075..2169 | CDD:206637 | 32/96 (33%) | ||
Cadherin_repeat | 2180..2289 | CDD:206637 | 25/109 (23%) | ||
Cadherin_repeat | 2301..2398 | CDD:206637 | 22/112 (20%) | ||
Cadherin_repeat | 2406..2504 | CDD:206637 | 33/98 (34%) | ||
Cadherin_repeat | 2513..2607 | CDD:206637 | 31/97 (32%) | ||
Cadherin_repeat | 2620..2718 | CDD:206637 | 31/97 (32%) | ||
Cadherin_repeat | 2735..2841 | CDD:206637 | 31/109 (28%) | ||
Cadherin_repeat | 2850..2951 | CDD:206637 | 25/131 (19%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 70 | 1.000 | Domainoid score | I9540 |
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100175 | |
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |