DRSC/TRiP Functional Genomics Resources

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Protein Alignment kug and pcdh2g17

DIOPT Version :10

Sequence 1:NP_001027138.2 Gene:kug / 40191 FlyBaseID:FBgn0261574 Length:4699 Species:Drosophila melanogaster
Sequence 2:NP_001019360.1 Gene:pcdh2g17 / 554064 ZFINID:ZDB-GENE-050610-7 Length:956 Species:Danio rerio


Alignment Length:700 Identity:200/700 - (28%)
Similarity:324/700 - (46%) Gaps:83/700 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   780 SINESVQLGETVAWIEAKDRDLGYNGKLVFA----ISDGDYDSVFRIDPDRGELQIIGYLDRER- 839
            ||.|.:..|..:..:.   :|||.:.|.:.:    |..|:......:..|:|.|.:...:|||: 
Zfish    42 SIPEEMSKGSLIGNVA---QDLGLDLKRLRSGRARIVTGESAQYAELKTDKGILVVSERIDREQL 103

  Fly   840 ---------QNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTV 895
                     ..|.:|.       ||.:  ...:.:.|:|||||.|..:|....|.::|||..|:.
Zfish   104 CGDVTPCSFSFEIILE-------NPIE--LHQVTVEIIDVNDNSPAFEKNKMNFEISESATPGSR 159

  Fly   896 VHCLHATDADSGINAQVTYALSVECSDFTVNATTGC-------LRLNKPLDREKQDNYALHITAK 953
            .....|.|||..:|:...|.|: ..:.|.:...:..       :.|:|.||||:..:.:|.:.|.
Zfish   160 FALESAHDADVELNSLQNYILT-RNNYFVLKQQSNPDGSRYVEMVLDKALDREEHPHLSLKLIAV 223

  Fly   954 DGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFS 1018
            |||:|..|....:.|.|.|||||||||....|...|.|:.|:||.:..:.|.|.|.|.|..|..|
Zfish   224 DGGNPQRSGSVNIDVTVLDVNDNAPVFNQTVYRASVTENAPKGTYITTVNATDADSGSNGHITLS 288

  Fly  1019 ---LKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVN 1080
               |||  |...:|.||::||.:...|.:|:|..:...:.|.|.|.|  .|||...::|.::|||
Zfish   289 FSDLKE--QSRGIFNIDENTGLVSVLGNIDFEKDKRFEIRVKATDQG--GLTSTSKLIIEVVDVN 349

  Fly  1081 ENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMD-------TVDLNSKITYSITGGDGLGIFA 1138
            :|  ||..........|.|:.|.||.:..|..:|.|       :..:|..|.:.|..       :
Zfish   350 DN--APVITLMSLSSPVSEDAPPGTTIAVVNIKDSDSGRNGQVSCFINENIPFKIKS-------S 405

  Fly  1139 VNDQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVT 1203
            :::..::.:.:.||.||::.:.:|:.|.|.....||:...|.::|.:.|||.|:.|:..|...:.
Zfish   406 LSNYYNLITDAFLDRETQSQFNITVTATDSGSPALSSSKTVSLKVSDINDNAPIFDQKSYSAQLI 470

  Fly  1204 EASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVG-----YFEIDSKTGVIKTTERKLDRENQA 1263
            |.:...:.|.::.|.|.|.:....::|.:...::.|     |..|:::.||:... |..|.|...
Zfish   471 ENNTPGLSICSVTARDLDWNQNSRVSYYLEDAHISGVPISSYVSINAENGVLHAV-RSFDYEQVK 534

  Fly  1264 EHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQ---------VPSSATVNQSIF 1319
            :....|...|.|||.|||...:.:.:.|.|||:|   |.:|.||         ||.||.|...:.
Zfish   535 QFSFIVKAQDGGSPPLSSNVSVKILIQDQNDNAP---QILYPVQSGASVVAEIVPRSADVGYLVT 596

  Fly  1320 QVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPL-DSDN-EFEIHIKAEDNGIPKK 1382
            :|.|:|.|||:|..::|.:.....:..|.:.:|.|.|...:.: |.|. :..:.:..||||.|.:
Zfish   597 KVVAVDVDSGQNAWLSYKLHKATDRALFEVGAQNGEIRTVRQVTDKDAVKQRLTVVVEDNGQPSR 661

  Fly  1383 SQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAV 1432
            |.|..||:.|      :.:.|.::.:.::...|...||...|.:...|||
Zfish   662 SATVNVNVAV------ADSFPEVLSEFTDFTHDKEYNDNLTFYLVLALAV 705

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kugNP_001027138.2 Cadherin_repeat 66..178 CDD:206637
Cadherin_repeat 187..285 CDD:206637
Cadherin_repeat 404..503 CDD:206637
Cadherin_repeat 513..609 CDD:206637
Cadherin_repeat 622..708 CDD:206637
Cadherin_repeat 776..873 CDD:206637 24/106 (23%)
Cadherin_repeat 883..976 CDD:206637 31/99 (31%)
Cadherin_repeat 984..1082 CDD:206637 36/100 (36%)
Cadherin_repeat 1092..1189 CDD:206637 23/103 (22%)
Cadherin_repeat 1197..1295 CDD:206637 25/102 (25%)
Cadherin_repeat 1303..1386 CDD:206637 28/93 (30%)
Cadherin_repeat 1413..1502 CDD:206637 6/19 (32%)
Cadherin_repeat 1510..1608 CDD:206637
Cadherin_repeat 1621..1713 CDD:206637
Cadherin_repeat 1724..1811 CDD:206637
Cadherin_repeat 1819..1927 CDD:206637
Cadherin_repeat 1948..2030 CDD:206637
Cadherin_repeat 2037..2136 CDD:206637
Cadherin_repeat 2144..2235 CDD:206637
Cadherin_repeat 2246..2336 CDD:206637
Cadherin_repeat 2345..2445 CDD:206637
Cadherin_repeat 2453..2545 CDD:206637
Cadherin_repeat 2555..>2633 CDD:206637
Cadherin_repeat 2658..2759 CDD:206637
Cadherin_repeat 2774..2856 CDD:206637
Cadherin_repeat 2865..2963 CDD:206637
Cadherin_repeat 2974..3063 CDD:206637
Cadherin_repeat 3072..3165 CDD:206637
Cadherin_repeat 3173..3269 CDD:206637
Cadherin_repeat 3277..3374 CDD:206637
Cadherin_repeat 3383..3479 CDD:206637
Cadherin_repeat 3488..3579 CDD:206637
Cadherin_repeat 3590..3681 CDD:206637
EGF_CA 3866..3903 CDD:238011
Laminin_G_2 3953..4077 CDD:460494
EGF_CA <4121..4150 CDD:238011
EGF_CA 4152..4189 CDD:238011
EGF_CA 4195..4225 CDD:238011
EGF_CA 4227..4262 CDD:214542
pcdh2g17NP_001019360.1 Cadherin_2 38..120 CDD:462413 18/87 (21%)
Cadherin_repeat 147..246 CDD:206637 31/99 (31%)
Cadherin_repeat 254..351 CDD:206637 36/100 (36%)
Cadherin_repeat 364..456 CDD:206637 23/98 (23%)
Cadherin_repeat 464..566 CDD:206637 25/102 (25%)
Cadherin_repeat 585..673 CDD:206637 29/93 (31%)
Cadherin_C_2 694..778 CDD:465139 3/11 (27%)
Cadherin_tail 815..>913 CDD:435046
Blue background indicates that the domain is not in the aligned region.

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