Protein Alignment kug and pcdh1g32

DIOPT Version :10

• Sequence 1: NP_001027138.2
• Gene: kug / 40191
• FlyBaseID: FBgn0261574
• Length: 4699
• Species: Drosophila melanogaster
• Sequence 2: NP_001019299.3
• Gene: pcdh1g32 / 554016
• ZFINID: ZDB-GENE-050609-25
• Length: 945
• Species: Danio rerio
• Alignment Length: 856
• Identity: 233/856 - (27%)
• Similarity: 374/856 - (43%)
• Gaps: 135/856 - (15%)

  Fly   767 VHRPEFVNFPQEL--SINESVQLGETVAWIEAKDRDLGYNGKLVF-----AISDGDYDSVFRIDP 824
            :|...|.....||  |..|..:.|..|..:   .:|||.:..::.     .||:.: |..|.:|.
Zfish    20 LHALCFATHASELLYSTAEESKPGTIVGHL---TKDLGMDIHMIVLRQMRIISESN-DKYFNVDL 80

  Fly   825 DRGELQIIGYLDRE-----RQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATF 884
            ..|.|.|...:|||     |.:.:: .|.: .|.||.:..|  :.|.|:|||||.|..|....:.
Zfish    81 TSGALVIKETMDREILCGGRLHCHI-RIQI-SLQNPLEMHS--VSIEIVDVNDNAPQFQSQNTSL 141

  Fly   885 RLTESARIGTVVHCLHATDADSGINAQVTYALSV-ECSDFTVNATTG-----CLRLNKPLDREKQ 943
            .::|:|..||......|.|.|.|:|:...|.||. :|....::..:.     .|.|||||||||.
Zfish   142 EVSEAAAPGTSFRLESAHDPDVGVNSLRAYYLSQNDCFILKIDTKSDGSKIPILVLNKPLDREKM 206

  Fly   944 DNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDED 1008
            ..|.|.:||.||||...|..:.|::.:.|||||||.|........:.|:.|.||::.::.|.|.|
Zfish   207 SEYRLILTAVDGGSAEKSGNSAVFINILDVNDNAPHFLNPTKRVTLLENSPHGTLVTLLNASDAD 271

  Fly  1009 IGPNAEIQFSLKEETQDE--ELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMS 1071
            .|.|.||.::..:.|.|.  :||.:|..||.||..|.:|:|..:||::.|.|.|.|.|.:....:
Zfish   272 HGQNGEISYTFDKYTPDSVLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDKGMPPMEGSCN 336

  Fly  1072 IVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDT---VDLNSKITYSITGGDG 1133
            |.|.|||||:|  .||....:....:.|:...||.:..:..:|.||   .::|..|.|.:.
Zfish   337 IKIEIIDVNDN--TPEISINMVSSVISEDVTLGTVIALIKVKDEDTGKNGEVNLHIPYGLP---- 395

  Fly  1134 LGIFAVND--QGSITSLSQ--LDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTD 1194
               |.::.  :|..|.::.  ||.|....|.:|:.|.|....|.|:.....:.:.:.|||.|:..
Zfish   396 ---FKISSPYKGLFTLMADGLLDREAVAEYTITVTATDSGSPPRSSQKSFVLCLSDVNDNPPIFS 457

  Fly  1195 KPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVG-----YFEIDSKTGVIKTTE 1254
            :|.|.|::.|.:..|..::::.|.|||:....||:::|:....:|     |..|:..:|.|...
Zfish   458 QPSYSVDIAENNAPNAPLLSVSASDPDVGENSTISFSILESEALGLSVSSYVYINPNSGQIYAI- 521

  Fly  1255 RKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQ---------VPS 1310
            ||.|.|:.......|.:.|.|:|..||.:.:.|.:.|.||:.|..   :|...         :|.
Zfish   522 RKFDYEHLNAFQFVVQVQDRGTPSQSSNATVHVFIKDQNDHPPIL---IYPAPTSDGTLHFFIPR 583

  Fly  1311 SATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPL---DSDNEFEIHI 1372
            :|::...:.::..:|.|||.|..:.||| .|.....|.||:..|.:..|:.|   ||.:.|.:::
Zfish   584 TASIGHLVNRITFVDGDSGHNAWLFYSI-LGPDAEMFHIDAHTGELRTAQKLSEEDSKSVFSLNV 647

  Fly  1373 KAEDNGIPKKSQTARVNIVVVPVN--------------PNSQNAPLIVRKTSENVVDLTENDKPG 1423
            ..:|||.|.:|.:..|||.:...:              |...|..|.:..|...::..:
Zfish   648 IVKDNGRPSRSASVAVNITLAEKSSDVSSERRSLTSKTPTGSNLTLYLIITLSFIIAFS------ 706

  Fly  1424 FLVTQILAVDDDNDQLWYNISNGNDDNTFYIGQDNGNILLSKYLDYE----TQQSYNLTISV-TD 1483
            ||....:||.                   ::......|.|.:.|.::    ..|..:|.:.: ||
Zfish   707 FLAIIAIAVR-------------------WLSHHGYMICLMQKLGFKHTPRAHQHNDLHLQLNTD 752

  Fly  1484 GTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISE----------NIEEESVIMQLHATDRDEDKK 1538
            |.        ::.:::......|.|..|...:|.          ...|.::.|:|       .|:
Zfish   753 GP--------IRFMEVVGATQDFHKHAYTPGLSTISSRSDFVFVKAPESTLSMRL-------SKR 802

  Fly  1539 LFYHLHATQDP 1549
            ||.|....|.|
Zfish   803 LFAHSLMKQKP 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kug	NP_001027138.2	Cadherin_repeat	66..178	CDD:206637
		Cadherin_repeat	187..285	CDD:206637
		Cadherin_repeat	404..503	CDD:206637
		Cadherin_repeat	513..609	CDD:206637
		Cadherin_repeat	622..708	CDD:206637
		Cadherin_repeat	776..873	CDD:206637	31/108 (29%)
		Cadherin_repeat	883..976	CDD:206637	36/98 (37%)
		Cadherin_repeat	984..1082	CDD:206637	37/99 (37%)
		Cadherin_repeat	1092..1189	CDD:206637	22/103 (21%)
		Cadherin_repeat	1197..1295	CDD:206637	29/102 (28%)
		Cadherin_repeat	1303..1386	CDD:206637	26/94 (28%)
		Cadherin_repeat	1413..1502	CDD:206637	12/93 (13%)
		Cadherin_repeat	1510..1608	CDD:206637	11/50 (22%)
		Cadherin_repeat	1621..1713	CDD:206637
		Cadherin_repeat	1724..1811	CDD:206637
		Cadherin_repeat	1819..1927	CDD:206637
		Cadherin_repeat	1948..2030	CDD:206637
		Cadherin_repeat	2037..2136	CDD:206637
		Cadherin_repeat	2144..2235	CDD:206637
		Cadherin_repeat	2246..2336	CDD:206637
		Cadherin_repeat	2345..2445	CDD:206637
		Cadherin_repeat	2453..2545	CDD:206637
		Cadherin_repeat	2555..>2633	CDD:206637
		Cadherin_repeat	2658..2759	CDD:206637
		Cadherin_repeat	2774..2856	CDD:206637
		Cadherin_repeat	2865..2963	CDD:206637
		Cadherin_repeat	2974..3063	CDD:206637
		Cadherin_repeat	3072..3165	CDD:206637
		Cadherin_repeat	3173..3269	CDD:206637
		Cadherin_repeat	3277..3374	CDD:206637
		Cadherin_repeat	3383..3479	CDD:206637
		Cadherin_repeat	3488..3579	CDD:206637
		Cadherin_repeat	3590..3681	CDD:206637
		EGF_CA	3866..3903	CDD:238011
		Laminin_G_2	3953..4077	CDD:460494
		EGF_CA	<4121..4150	CDD:238011
		EGF_CA	4152..4189	CDD:238011
		EGF_CA	4195..4225	CDD:238011
		EGF_CA	4227..4262	CDD:214542
pcdh1g32	NP_001019299.3	None