Protein Alignment kug and pcdh1g30

DIOPT Version :10

• Sequence 1: NP_001027138.2
• Gene: kug / 40191
• FlyBaseID: FBgn0261574
• Length: 4699
• Species: Drosophila melanogaster
• Sequence 2: NP_001019297.2
• Gene: pcdh1g30 / 554014
• ZFINID: ZDB-GENE-050609-23
• Length: 949
• Species: Danio rerio
• Alignment Length: 657
• Identity: 200/657 - (30%)
• Similarity: 309/657 - (47%)
• Gaps: 69/657 - (10%)

  Fly   780 SINESVQLGETVAWIEAKDRDLGYN----GKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRE-- 838
            :|.|.::.|..|..|.   :|||::    .:....|:.......|.:|..:|:|.:.|.:|||
Zfish    33 TIPEELKEGSVVGNIA---KDLGFDISDIAERKLRIASESNRQYFSVDLGKGDLLVNGRIDRETL 94

  Fly   839 --RQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHA 901
              :.:..:::|.:. :.||.:..|  :.|.|.|:|||.|......||.:::|....||......|
Zfish    95 CGQSSGCLMSIQIV-IENPLQMHS--VEIEIQDINDNAPNFHTKDATLKISELIAPGTRFILESA 156

  Fly   902 TDADSGINAQVTYALSVECSDFTVNATTGCLRLN----------------KPLDREKQDNYALHI 950
            .|.|.|.|:..||:||          .....|||                ||||||||..:.|.:
Zfish   157 EDLDVGSNSLKTYSLS----------NNNYFRLNVKNLKDGRIGPELVVEKPLDREKQSMHKLIL 211

  Fly   951 TAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEI 1015
            ||.|||:||.|..:::.:.|.|:|||.|.|.:..|...:.|....|:.:..|:|.|.|.|.|.||
Zfish   212 TALDGGNPVKSGTSVLQIAVQDINDNEPKFELSAYKASILETAITGSNVLKIKATDLDEGLNGEI 276

  Fly  1016 QFSLKEETQD--EELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIID 1078
            |:.|...|.:  ..:|.::..||.|...|.||||.|:.:...|.|.|.|:|.|....|:.|.|||
Zfish   277 QYLLSAHTPEFVRNVFSVNADTGEITVTGTLDYETKKSYAFDVCAKDKGNPELEGQSSVQIDIID 341

  Fly  1079 VNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQG 1143
            .|:|  |||.........|.||...||.|..:|.:|:|:.| |.|:...::......:...::..
Zfish   342 ENDN--APEIILTSLPSPVPENATVGTVVALITVKDLDSGD-NGKVDLIVSPDVPFKLKPFHNHY 403

  Fly  1144 SITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVE 1208
            |:.:.|.||.|.:..|.:.:.|.|..:.|:.....|.|:|.:.|||.||..:..|.|.:.|.::.
Zfish   404 SLITDSLLDREVRPEYNVEIIAMDSGVPPIKTAKTVNIKVLDTNDNSPLFSQTSYNVYINENNLA 468

  Fly  1209 NVEIITLKAFDPDIDPTQTITYNIV-SG-NLV---GYFEIDSKTGVIKTTERKLDRENQAEHILE 1268
            ...:.::.|.|.|::....:||:|: || |.|   .||.|:|:.|.|.... ..|.|......:.
Zfish   469 GASLFSVSASDIDLNKNAFLTYSILDSGSNYVPASSYFYINSENGSIYCMS-TFDYEKVKLFSVV 532

  Fly  1269 VAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVY---------KVQVPSSATVNQSIFQVHAI 1324
            |...|.|||.|||.:.:.|.:||.|||:|..   :|         :.::|.|......:.:|.|:
Zfish   533 VQAKDQGSPSLSSNATVHVFILDQNDNAPAV---IYPSTSMGSVSQQRMPRSTKAGHLVTKVTAV 594

  Fly  1325 DSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPL----DSDNEFEIHIKAEDNGIPKKSQT 1385
            |:|||.|..:.|.:......:.|.::...|.:...:.:    ||.....|.||  |||.|.:|.|
Zfish   595 DADSGHNAWLFYRLAEATDTSLFSVNLHTGEVRTKRAVSEHDDSSQRLVIEIK--DNGEPIQSTT 657

  Fly  1386 ARVNIVV 1392
            ..|:|::
Zfish   658 VTVDILI 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kug	NP_001027138.2	Cadherin_repeat	66..178	CDD:206637
		Cadherin_repeat	187..285	CDD:206637
		Cadherin_repeat	404..503	CDD:206637
		Cadherin_repeat	513..609	CDD:206637
		Cadherin_repeat	622..708	CDD:206637
		Cadherin_repeat	776..873	CDD:206637	25/100 (25%)
		Cadherin_repeat	883..976	CDD:206637	36/108 (33%)
		Cadherin_repeat	984..1082	CDD:206637	36/99 (36%)
		Cadherin_repeat	1092..1189	CDD:206637	25/96 (26%)
		Cadherin_repeat	1197..1295	CDD:206637	33/102 (32%)
		Cadherin_repeat	1303..1386	CDD:206637	23/95 (24%)
		Cadherin_repeat	1413..1502	CDD:206637
		Cadherin_repeat	1510..1608	CDD:206637
		Cadherin_repeat	1621..1713	CDD:206637
		Cadherin_repeat	1724..1811	CDD:206637
		Cadherin_repeat	1819..1927	CDD:206637
		Cadherin_repeat	1948..2030	CDD:206637
		Cadherin_repeat	2037..2136	CDD:206637
		Cadherin_repeat	2144..2235	CDD:206637
		Cadherin_repeat	2246..2336	CDD:206637
		Cadherin_repeat	2345..2445	CDD:206637
		Cadherin_repeat	2453..2545	CDD:206637
		Cadherin_repeat	2555..>2633	CDD:206637
		Cadherin_repeat	2658..2759	CDD:206637
		Cadherin_repeat	2774..2856	CDD:206637
		Cadherin_repeat	2865..2963	CDD:206637
		Cadherin_repeat	2974..3063	CDD:206637
		Cadherin_repeat	3072..3165	CDD:206637
		Cadherin_repeat	3173..3269	CDD:206637
		Cadherin_repeat	3277..3374	CDD:206637
		Cadherin_repeat	3383..3479	CDD:206637
		Cadherin_repeat	3488..3579	CDD:206637
		Cadherin_repeat	3590..3681	CDD:206637
		EGF_CA	3866..3903	CDD:238011
		Laminin_G_2	3953..4077	CDD:460494
		EGF_CA	<4121..4150	CDD:238011
		EGF_CA	4152..4189	CDD:238011
		EGF_CA	4195..4225	CDD:238011
		EGF_CA	4227..4262	CDD:214542
pcdh1g30	NP_001019297.2	Cadherin_2	29..111	CDD:462413	18/81 (22%)
		Cadherin_repeat	138..237	CDD:206637	36/108 (33%)
		Cadherin_repeat	246..345	CDD:206637	36/98 (37%)
		Cadherin_repeat	358..449	CDD:206637	25/91 (27%)
		Cadherin_repeat	457..559	CDD:206637	33/102 (32%)
		Cadherin_repeat	579..666	CDD:206637	25/88 (28%)
		Cadherin_C_2	689..>720	CDD:465139
		Cadherin_tail	816..>912	CDD:435046