Protein Alignment kug and pcdh1gc5

DIOPT Version :10

• Sequence 1: NP_001027138.2
• Gene: kug / 40191
• FlyBaseID: FBgn0261574
• Length: 4699
• Species: Drosophila melanogaster
• Sequence 2: NP_001012674.4
• Gene: pcdh1gc5 / 503571
• ZFINID: ZDB-GENE-041118-16
• Length: 948
• Species: Danio rerio
• Alignment Length: 657
• Identity: 201/657 - (30%)
• Similarity: 298/657 - (45%)
• Gaps: 68/657 - (10%)

  Fly   780 SINESVQLGETVAWIEAKDRDLGY----NGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRER- 839
            :|.|.::.|..|..| |||..|..    |.||..|...|  ...|.:|...|||.:.|.:|||.
Zfish    31 TIPEELKEGSVVGNI-AKDIGLDIVHIANRKLRIASDSG--TQFFSVDTRSGELIVNGRIDREAL 92

  Fly   840 --QNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHAT 902
              |::..|......:.:|.:  ...:.|.|.|:|||.|.........::.||..:|.......|.
Zfish    93 CGQSDSCLMPLQLIIEDPLQ--LYRINIEIQDINDNAPNFHTKDNVLKIAESVAVGAKFPFESAE 155

  Fly   903 DADSGINAQVTYALSVECSDFTVNATTGCLRLN----------------KPLDREKQDNYALHIT 951
            |.|.|.|:..:|||:          ..|..|||                ||||||||..:.|.:|
Zfish   156 DLDVGSNSLKSYALN----------NNGFFRLNVKTVEDGKKVPELIVDKPLDREKQSVHKLILT 210

  Fly   952 AKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQ 1016
            |.|||.||.|....:.|:|.|.|||.|.|...:|...|.|....|:.:..::|.|.|.|.|.|||
Zfish   211 ALDGGDPVKSGTIAIQVIVQDTNDNEPKFEHSQYKASVLESTKPGSSVLTVKATDFDEGLNGEIQ 275

  Fly  1017 FSLKEETQD--EELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDV 1079
            :.....|.|  ::.|.|:..||.|...|.||||..:::...|.|.|.|.|......|:.:.|||.
Zfish   276 YFFGAHTPDAVKKCFNINTDTGDITVIGILDYEVTKLYTFDVCAKDKGSPEQEGHSSVRLHIIDE 340

  Fly  1080 NENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIF-AVNDQG 1143
            |:|  .||.........|.||...||.|..:..:|:|:.| |.|:..:|:......:. |.::..
Zfish   341 NDN--IPEIILTSLPSPVSENATVGTVVALINVKDLDSGD-NGKVNLTISSRFPFKLKPAFDNHY 402

  Fly  1144 SITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVE 1208
            |:.:.|.||.|.|..|.:.|.|.|....||.:...|.:::.:.|||.||..:|.|.|.:.|.|:.
Zfish   403 SLVTDSLLDREAKAEYEIQLVATDSGSPPLKSTKTVNVRLLDVNDNPPLFSQPSYTVYIKENSLP 467

  Fly  1209 NVEIITLKAFDPDIDPTQTITYNI--VSGNLV---GYFEIDSKTGVIKTTERKLDRENQAEHILE 1268
            ...:.::.|.|.|.|....::|::  :|.:.:   .||.|:|:.|.|.:.. ..|.|......:.
Zfish   468 GASLFSISATDIDKDRNAMLSYSVLDLSSSQIPASSYFYINSENGTIYSMS-SFDYEKMKLISIV 531

  Fly  1269 VAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVY---------KVQVPSSATVNQSIFQVHAI 1324
            |...|.|||.|||.:.:.|.:||.|||:|..   :|         ..::|.||.....:.:|.|:
Zfish   532 VQAKDQGSPFLSSNATVHVFILDQNDNAPAV---IYPSTSMGSVSHQRMPRSAKAGHLVTKVTAV 593

  Fly  1325 DSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPL----DSDNEFEIHIKAEDNGIPKKSQT 1385
            |:|||.|..:.|.:......:.|.::...|.:...:.:    ||.....:.||  |||.|.:|.|
Zfish   594 DADSGHNAWLFYRLAEATDASLFSVNLHTGEVRTKRAVSEHDDSSQRLVLEIK--DNGDPIQSTT 656

  Fly  1386 ARVNIVV 1392
            ..|:|::
Zfish   657 VTVDILI 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kug	NP_001027138.2	Cadherin_repeat	66..178	CDD:206637
		Cadherin_repeat	187..285	CDD:206637
		Cadherin_repeat	404..503	CDD:206637
		Cadherin_repeat	513..609	CDD:206637
		Cadherin_repeat	622..708	CDD:206637
		Cadherin_repeat	776..873	CDD:206637	30/99 (30%)
		Cadherin_repeat	883..976	CDD:206637	36/108 (33%)
		Cadherin_repeat	984..1082	CDD:206637	34/99 (34%)
		Cadherin_repeat	1092..1189	CDD:206637	27/97 (28%)
		Cadherin_repeat	1197..1295	CDD:206637	30/102 (29%)
		Cadherin_repeat	1303..1386	CDD:206637	23/95 (24%)
		Cadherin_repeat	1413..1502	CDD:206637
		Cadherin_repeat	1510..1608	CDD:206637
		Cadherin_repeat	1621..1713	CDD:206637
		Cadherin_repeat	1724..1811	CDD:206637
		Cadherin_repeat	1819..1927	CDD:206637
		Cadherin_repeat	1948..2030	CDD:206637
		Cadherin_repeat	2037..2136	CDD:206637
		Cadherin_repeat	2144..2235	CDD:206637
		Cadherin_repeat	2246..2336	CDD:206637
		Cadherin_repeat	2345..2445	CDD:206637
		Cadherin_repeat	2453..2545	CDD:206637
		Cadherin_repeat	2555..>2633	CDD:206637
		Cadherin_repeat	2658..2759	CDD:206637
		Cadherin_repeat	2774..2856	CDD:206637
		Cadherin_repeat	2865..2963	CDD:206637
		Cadherin_repeat	2974..3063	CDD:206637
		Cadherin_repeat	3072..3165	CDD:206637
		Cadherin_repeat	3173..3269	CDD:206637
		Cadherin_repeat	3277..3374	CDD:206637
		Cadherin_repeat	3383..3479	CDD:206637
		Cadherin_repeat	3488..3579	CDD:206637
		Cadherin_repeat	3590..3681	CDD:206637
		EGF_CA	3866..3903	CDD:238011
		Laminin_G_2	3953..4077	CDD:460494
		EGF_CA	<4121..4150	CDD:238011
		EGF_CA	4152..4189	CDD:238011
		EGF_CA	4195..4225	CDD:238011
		EGF_CA	4227..4262	CDD:214542
pcdh1gc5	NP_001012674.4	None