Protein Alignment kug and pcdh10b

DIOPT Version :10

• Sequence 1: NP_001027138.2
• Gene: kug / 40191
• FlyBaseID: FBgn0261574
• Length: 4699
• Species: Drosophila melanogaster
• Sequence 2: NP_878305.1
• Gene: pcdh10b / 360138
• ZFINID: ZDB-GENE-030721-4
• Length: 1026
• Species: Danio rerio
• Alignment Length: 676
• Identity: 210/676 - (31%)
• Similarity: 318/676 - (47%)
• Gaps: 55/676 - (8%)

  Fly   780 SINESVQLGETVAWIEAKDRDLGYN-GKLV---FAISDGDYDSVFRIDPDRGELQIIGYLDRER- 839
            |:.|..:.|..|..|.   .|||.: .||.   |.:..........::.:.|.|.:...:||||
Zfish    21 SVPEEAEHGTFVGNIA---EDLGLDLTKLSSRRFQVVPSSRTPYLEVNLENGVLFVNEKIDRERI 82

  Fly   840 ---QNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHA 901
               ....:|::.|: |.||.:..  .:.|.::|:|||.|...:|..|..::|||..||......|
Zfish    83 CKQSASCLLHLEVF-LENPLELF--RVEIEVVDINDNPPSFPETDFTVEISESATPGTRFPLESA 144

  Fly   902 TDADSGINAQVTYALSVECSDFTVN---------ATTGC----LRLNKPLDREKQDNYALHITAK 953
            .|.|.|.||..||       |.|.|         .|.|.    |.|.||||||:|..:...:||.
Zfish   145 FDPDVGSNALRTY-------DITTNNYFYLDVQTQTDGNKFAELVLEKPLDREQQAMHRYVLTAV 202

  Fly   954 DGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFS 1018
            |||.|..:..||:.|.|.|.|||.|||....|...:.|:.|.||::..:.|.|.|.|||.|:.:|
Zfish   203 DGGQPPRTGTALLVVRVLDSNDNVPVFDQPVYSVNLAENAPVGTLVIQLNATDSDEGPNGEVIYS 267

  Fly  1019 LKE--ETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNE 1081
            ...  .::.:|||.||..||.|..:|.:|:|...::.:.|.|.|.|..::.:...:::.:.|||:
Zfish   268 FSNHISSRVKELFDIDARTGRIEVRGEVDFEESGLYQIYVQAKDMGPNAVPAHCKVLVKVTDVND 332

  Fly  1082 NRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGI-FAVNDQGSI 1145
            |  |||.........|.||...||.:..::..|.|:.| |.:....|.|.....: .:..:..:|
Zfish   333 N--APEIIFSTVTESVSENAATGTVIALLSVTDKDSED-NGQTHVEILGDVPFKLKTSFRNYYTI 394

  Fly  1146 TSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENV 1210
            .:...|:.||...|.:|:.|:|..|..|:....:.:.|.:||||.|...:|||.|.|||.:|...
Zfish   395 VTDGPLNRETVEAYTVTVVARDKGIPSLATSKSIKVHVSDENDNAPTFTQPVYDVYVTENNVPGA 459

  Fly  1211 EIITLKAFDPDIDPTQTITYNIVSGNLVG-----YFEIDSKTGVIKTTERKLDRENQAEHILEVA 1270
            .|..:.|.|||:.....|||:||...:.|     |..|:|:.|.:... |..|.|...:....|.
Zfish   460 YIYAVSAVDPDVGQNAYITYSIVECEIQGMSVVTYVSINSENGYLYAL-RSFDYEQLKDFSFMVQ 523

  Fly  1271 ISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYK-----VQVPSSATVNQSIFQVHAIDSDSGE 1330
            ..|:|||.|.|.:.:.|.::|.|||:|.....|.|     ..:|.||.....:.::.|:|:|.||
Zfish   524 ARDSGSPELWSNATVNVIIVDQNDNAPSVIAPVGKNGTAREPLPRSAEPGYLVTRIVAMDADDGE 588

  Fly  1331 NGRITYSIKSGKGKNKFRIDSQRGHIHIAKPL----DSDNEFEIHIKAEDNGIPKKSQTARVNIV 1391
            |.|::|||:.|.....||:|.:.|.:..|:.:    |....:|:.|:..|:|.|..|.:|.|.:.
Zfish   589 NARLSYSIQRGNENGMFRMDWRTGELRTARRVSVKRDPQQLYELLIEVRDHGQPPMSCSAVVQVT 653

  Fly  1392 VVPVNPNSQNAPLIVRKTSENVVDLT 1417
            :|.......:......|..:..:|||
Zfish   654 LVDSLVEGHSGERGTAKAKDASLDLT 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kug	NP_001027138.2	Cadherin_repeat	66..178	CDD:206637
		Cadherin_repeat	187..285	CDD:206637
		Cadherin_repeat	404..503	CDD:206637
		Cadherin_repeat	513..609	CDD:206637
		Cadherin_repeat	622..708	CDD:206637
		Cadherin_repeat	776..873	CDD:206637	25/100 (25%)
		Cadherin_repeat	883..976	CDD:206637	40/105 (38%)
		Cadherin_repeat	984..1082	CDD:206637	31/99 (31%)
		Cadherin_repeat	1092..1189	CDD:206637	24/97 (25%)
		Cadherin_repeat	1197..1295	CDD:206637	35/102 (34%)
		Cadherin_repeat	1303..1386	CDD:206637	28/91 (31%)
		Cadherin_repeat	1413..1502	CDD:206637	3/5 (60%)
		Cadherin_repeat	1510..1608	CDD:206637
		Cadherin_repeat	1621..1713	CDD:206637
		Cadherin_repeat	1724..1811	CDD:206637
		Cadherin_repeat	1819..1927	CDD:206637
		Cadherin_repeat	1948..2030	CDD:206637
		Cadherin_repeat	2037..2136	CDD:206637
		Cadherin_repeat	2144..2235	CDD:206637
		Cadherin_repeat	2246..2336	CDD:206637
		Cadherin_repeat	2345..2445	CDD:206637
		Cadherin_repeat	2453..2545	CDD:206637
		Cadherin_repeat	2555..>2633	CDD:206637
		Cadherin_repeat	2658..2759	CDD:206637
		Cadherin_repeat	2774..2856	CDD:206637
		Cadherin_repeat	2865..2963	CDD:206637
		Cadherin_repeat	2974..3063	CDD:206637
		Cadherin_repeat	3072..3165	CDD:206637
		Cadherin_repeat	3173..3269	CDD:206637
		Cadherin_repeat	3277..3374	CDD:206637
		Cadherin_repeat	3383..3479	CDD:206637
		Cadherin_repeat	3488..3579	CDD:206637
		Cadherin_repeat	3590..3681	CDD:206637
		EGF_CA	3866..3903	CDD:238011
		Laminin_G_2	3953..4077	CDD:460494
		EGF_CA	<4121..4150	CDD:238011
		EGF_CA	4152..4189	CDD:238011
		EGF_CA	4195..4225	CDD:238011
		EGF_CA	4227..4262	CDD:214542
pcdh10b	NP_878305.1	Cadherin_2	17..99	CDD:462413	20/81 (25%)
		Cadherin_repeat	125..225	CDD:206637	40/106 (38%)
		Cadherin_repeat	233..333	CDD:206637	31/99 (31%)
		Cadherin_repeat	345..438	CDD:206637	24/93 (26%)
		Cadherin_repeat	446..548	CDD:206637	35/102 (34%)
		Cadherin_repeat	566..656	CDD:206637	28/89 (31%)
		Cadherin_C_2	677..809	CDD:465139	3/3 (100%)