DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kug and Fat2

DIOPT Version :9

Sequence 1:	NP_001027138.2	Gene:	kug / 40191	FlyBaseID:	FBgn0261574	Length:	4699	Species:	Drosophila melanogaster
Sequence 2:	NP_001025159.1	Gene:	Fat2 / 245827	MGIID:	2685369	Length:	4351	Species:	Mus musculus

Alignment Length:	4424	Identity:	1423/4424 - (32%)
Similarity:	2223/4424 - (50%)	Gaps:	409/4424 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 HTATLEYRLENQLQDL-YRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLN-AE----VKY 102
            |.|..|..||..:..| :||:||:||.||.|||..|||.:       :.:::|:. ||    |||
Mouse    14 HRAACEKPLEETITPLTWRFTHSLYNATIYENSAPKTYVE-------SPVKMGMYLAEPHWVVKY 71

  Fly   103 RIISGDKEKLFKAEEKLVGDFAFLAIRTRTNN-VVLNREKTEEYVIRVKAHVHLHDRNVSSYETE 166
            ||||||...:||.||.:||:|.||.|||:::| .:||||..:.|.:.|:|    .|::: .:|..
Mouse    72 RIISGDAAGVFKTEEHVVGNFCFLRIRTKSSNTALLNREVRDSYTLVVQA----SDKSL-EFEAL 131

  Fly   167 ANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAI 231
            ..:.:.:||:|||.|||.|..|...|.||.|....|.||||.|||||.|.|.||:....||.|||
Mouse   132 TQVVVHILDQNDLKPLFSPPSYRFTISEDRPLKSPICKVTATDADLGQNAEFYYAFNARSEVFAI 196

  Fly   232 HPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTF 296
            |||:|.:|:..:|.......:||.|:|.||...::..|...:...:.|.|:.|:...|.|   |.
Mouse   197 HPTSGVVTVAGKLNVTWRGKYELQVLAVDRMRKISEGNGFGNLAPLVIYVEPVHRKPPVI---TL 258

  Fly   297 SSVTPTSNPL--IYGIVRVNDKDTGINGNIGRLEIVDGNPDGTF-LLKAAETKDEYYI----ELN 354
            ..:.|.....  ||..|.|:...:|  ..:..||:|.|:|...| :||:....:|:.:    ::|
Mouse   259 VVLNPPEGDEGDIYATVTVDTNGSG--AEVDSLEVVGGDPGKYFKVLKSYAQGNEFNLVAVRDIN 321

  Fly   355 QFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSV--PIQIKPESKNIPIFTQEIYEVSIPETAPINM 417
            ...||:.    :|::|...   :..||..:|:  ...:.|.:.....|.:.:|.|.:.|.:|...
Mouse   322 WAEHLHG----FNISLQTH---SRSRFPSRSIIRAFHLPPYTLANLRFEKAVYRVKLSEFSPPGS 379

  Fly   418 PVIRLKVSDPDLGKNALVYLE--IVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQ 480
            .|..::|:      .||..|.  :...:....|::|..:|::.|.|.:|..:::.|.|.|..
Mouse   380 RVALVRVT------TALPTLRYALKPSSGSTVFKLNARTGLITTTKPVDFHEQNQYQLHVKT--- 435

  Fly   481 ANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYS 545
                |..|::..|.|.:.|.|::.|:|...:...:::||...|:.|:.:||.|:|.|:|.:|:||
Mouse   436 ----SLGQATTTVIIDIVDCNNHAPVFNRSSYEGTLDENIPPGTSVLTVTATDQDHGDNGHITYS 496

  Fly   546 IANLNAVPFEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNR 610
            ||...||||.||.:.|::.||..:|:|.|||.|...:||||||.|:|::.|:.:|:.:|::|||:
Mouse   497 IAGPKAVPFSIDPYLGVISTTKSMDYELMKRIYTFRVRASDWGSPFRQEKEVSVSLRLKNLNDNQ 561

  Fly   611 PQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLK 675
            |.||.|||...:.:.||:|..:...||||.|....:.|.:..|||...|:|:..||.:|:.....
Mouse   562 PMFEEVNCTVSLRQDAPVGKSIMAVSAIDMDELQNLKYEIVSGNEQDYFHLNHFSGVISLKRSFM 626

  Fly   676 KTTL---TNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETL 737
            ..|.   |...||::|:||.:::....:.|.:: :|...:..:       :|.:|||...:.:|:
Mouse   627 NLTAVRPTVYSLKITASDGKNYASPTTLKVTVV-KDPRSEVPV-------QCDKTGVLTHITKTI 683

  Fly   738 SLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFV-NFPQELSINESVQLGETVAWIEAKDRDL 801
            ..:.....:......|:.|    ..|..|.|.|:|. :|||.:.|.|.|.:...:|.:.|.|.|.
Mouse   684 LQSAGLQGQEMGEEDFTSL----GNYQINHHAPQFEDHFPQSIDILEQVPVNTPLAHLAATDPDP 744

  Fly   802 GYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPIT 866
            |::|:||:.|:||:.:..|.|:.:.|.|.:...||.|..:.||||:||||||.|.||:.|:|.:|
Mouse   745 GFHGRLVYVIADGNEEGCFDIELETGLLTVAAALDYETTSFYVLNVTVYDLGTPPKSSWKLLTVT 809

  Fly   867 ILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGC 931
            :.|.||..|..........::|...:||.|..|...|.||..|.:|.|.|......|:::..||.
Mouse   810 VKDWNDKPPRFPPGGYQLTISEDTEVGTTVAELKTRDTDSEDNGRVRYTLLTPTEKFSLHPLTGE 874

  Fly   932 LRLNKPLDREKQDNYALHITAKDGGSPV----LSSEALVYVLVDDVNDNAPVFGVQEYIFKVRED 992
            |.:...||||.:..|.|...|:|  .|.    |.|...|.|.::|:|||.|....:....||.||
Mouse   875 LVVTGQLDRESEPQYILKAEARD--QPTKGHQLFSVTDVIVTLEDINDNPPQCITEHSSLKVPED 937

  Fly   993 LPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVS 1057
            :|.||||..::|.|.|:||..|:::.|.::...  .||:|..|||:..:..||:|.:..:||...
Mouse   938 MPLGTVLTFLDASDPDLGPAGEVKYILVDDVHG--TFRVDPMTGALSLEKELDFERRAGYNLSFW 1000

  Fly  1058 AIDGGDPSLTSDM-SIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLN 1121
            |.|.|.|.....: .:.::::|||||..:|.|..|||:|:|:||.|.||.||.|||:|.|: .|:
Mouse  1001 ASDSGRPLARRTLCHVEVLVMDVNENLHSPHFSSFVYQGQVQENSPAGTQVMVVTAQDDDS-GLD 1064

  Fly  1122 SKITYSITGGDGLGIFAVN-DQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVEN 1185
            .::.|.:..|.||..|::| |.|.:.:|:.||.|...:||||:.|.|...||||...||||:|.:
Mouse  1065 GELQYFLRAGTGLEAFSINQDTGMLETLAPLDREFTPYYWLTVLAVDRGSVPLSAVTEVYIEVTD 1129

  Fly  1186 ENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVI 1250
            .|||||...:||:|.:|.|.:.....::.|:|:|||......:|:|:.|||.:|:|.:...||::
Mouse  1130 INDNIPSMSRPVFYPSVKEDAPLGTSVLQLEAWDPDFSSQGKLTFNLTSGNHMGHFIVHPFTGLL 1194

  Fly  1251 KTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPS--SAT 1313
             :|.::|||||:.|::|||.:.|||.|.|.||||:||.|||:|||||.|..:::.|::..  |..
Mouse  1195 -STAKQLDRENKDEYVLEVTVQDNGDPPLRSTSRVVVCVLDVNDNSPMFSHKLFNVRLSERLSPL 1258

  Fly  1314 VNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNG 1378
            ..:.::::.|.|.|.|.||.|||||:. ..:..||||...|.:..:....:.....:.|||.|:|
Mouse  1259 SPEPVYRLVASDPDEGLNGSITYSIEE-SDEESFRIDPVTGVVSSSSTFAAGEYNILTIKATDSG 1322

  Fly  1379 IPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQLWYNI 1443
            .|..|.:.|::|..:| .|...:.||...::..:.. :.|.|....:: .:::|:......|::|
Mouse  1323 QPALSTSVRLHIEWIP-QPRPSSIPLSFDESHYSFA-VMETDPVNHML-GVISVEGRPGLFWFHI 1384

  Fly  1444 SNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNL-LVQVIDINDNPPQFA 1507
            |:|:.|..|.|.:..|:|::::.||...:.|||||:.||||..|..|.: ::.:.:||.:.|||.
Mouse  1385 SDGDKDMDFDIEKTTGSIVIARPLDTRRKSSYNLTVEVTDGFHTIATQVHILMIANINHHRPQFL 1449

  Fly  1508 KDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDF 1572
            :|.|.:.:.::......::::.|||:|..|.|.|.:|:::||.|..||::|..||.::....||.
Mouse  1450 QDHYDIRVPQDTLPGVELLRVQATDQDHGKGLIYTIHSSRDPGSANLFQLDPSSGVLVTVGTLDL 1514

  Fly  1573 EK-TAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRA 1636
            .. .:||||.|.|:||..|.|||:..:.::|.|.|.|.|.||....::.||::...|::|.:|||
Mouse  1515 HSGPSQHILTVMVRDQEMPIKRNFVWVTIHVEDGNLHSPHFTQPRYEANVPDTTTPGTELLQVRA 1579

  Fly  1637 IDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQI 1701
            :|.|.|.|||:.||.:.||....|.||...||||:|..|:...:..:.|.|||.|.|:|......
Mouse  1580 VDADRGANAEVHYSFLKGNSEGFFNIDSLLGIITVAQRLDHVHLNRHALTVKAEDQGSPQRHDLA 1644

  Fly  1702 PVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFNIISGNINESFRINPST 1766
            .|.:.|..|::..|.|..:...|||.|::|||:.:..::|.|||.:.:.:..||.|..|.:|..:
Mouse  1645 MVVVHVHPSDSSAPIFSKDEYFIEIPESVPIGSPILLISAASSSDVTYELREGNKNSVFSMNSYS 1709

  Fly  1767 GVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIG 1831
            |:|.....:|:|.:..:.|.::|:|||...:....:::|:|.|||.|.|:::.:||.:.|:|.:.
Mouse  1710 GLISTQKRLDHEKVSSYQLKIRGSNMAGVFTEVVALVYIIDENDNAPAFLKSTFVGHISEAAPLH 1774

  Fly  1832 SYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGY 1896
            |.:|...:|.   |.::..|:|...|.::.|.|::..|..|||||.:.|.:.:..:|||||...:
Mouse  1775 SLILGEDNSP---LVIRASDSDQEANSLLVYKILEPEALKFFKIDPSMGTLTITSELDYETTPLF 1836

  Fly  1897 TFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDADN 1961
            .|.:.|.|.|.|.|.:..:|.|.|.|.:|||.||.|:|:...|.:..|....:.:..|.|:|.|:
Mouse  1837 QFSIYVHDQGTPILFAPRSARVIIHVRDVNDSPPRFSEQIYEVAVVEPIHPGMELLTVQAEDNDS 1901

  Fly  1962 DTLRFDIVDGNTNECFQIEKYTGIITTRN------FEILNNENDRDYALHVRASDGIFSAILIVK 2020
             .:.:.|...||:|...|...||.|:..|      |..||          :||.||::....:||
Mouse  1902 -KVTYSIKTSNTDEAVTIHPITGQISVVNPAALRLFPKLN----------IRAFDGLYQDTAVVK 1955

  Fly  2021 IKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGA 2085
            |.:..|:|.:..|.::.||....||......:.::.|.||.|::.:.|.:||.|.||.:..|:|.
Mouse  1956 ISLTQALDKSLQFDQDIYRARVTENTPHSNVLVILGVHGNHLNDTLSYFLLNGTDLFHMVKSAGV 2020

  Fly  2086 LKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTS--IDISVLDVNDNCPLFVNMPYYAT 2148
            |:|.||.||||.:|.:.:.||.:       ::.|.|.|..  :.:||.|||||.|.|.::|||..
Mouse  2021 LQTRGVTFDREQQDTHEVAVEVR-------DNRVPRRVAQALVRVSVEDVNDNIPEFQHLPYYTV 2078

  Fly  2149 VSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNGE---LFKLDRKSGELSIKQHVEGHNRN-Y 2209
            :......|.::.||.|.|.|...||.|.|    |..|   .|::|...|::|:|:..:....| |
Mouse  2079 IQDGTEPGDVLFQVSATDKDLGANGTVTY----GFAEDYAYFRIDPYVGDISLKKPFDYQALNKY 2139

  Fly  2210 ELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSL 2274
            .|.|.|.|....|..:|..:.|.|.::|.|:|:..:|.|.|.|::.:|:.: :..:|.||.|..|
Mouse  2140 HLRVTARDAGTPPLQTEVEVHVTVRNKSNPLFQSPYYKVKVPENITLYTPI-LHTQARSPEGLRL 2203

  Fly  2275 IYTISSES--QSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDC 2337
            ||.|..|.  ..|..|:.||.:.|...||||..:.|..::||||:..|.::|..:.|.:.|:||.
Mouse  2204 IYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKNKHVFTVRATDTALGSFSEATVEVLVEDINDN 2268

  Fly  2338 YPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLY 2402
            .|.....:|:.::.|.:...|.::::.|:|.|||.|..:||.|.. :|.:.|:.|.|:.:.|.::
Mouse  2269 PPTFSQLVYSTSVSEGSPAQTPVIQLLASDQDSGQNQDVSYQIVE-DGSDVSKFFRINGSTGEMF 2332

  Fly  2403 LKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQF 2467
            ....||||..::..:.|...|.|.|.|:..:.|.:.|.|:|||.|.|.||.|...||..|..|..
Mouse  2333 TIQELDYEAHQHFRVKVRATDRGDPPLTGETLVVVNVSDINDNPPEFREPQYEANVSELATCGHL 2397

  Fly  2468 VALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHT 2532
            |...:|.|.||.||..|||.|:.||:.:.:||:..:|:||:.|:......||..|.:..||||..
Mouse  2398 VLKVQALDPDIGDTSRLEYLILSGNQDRHFSINSTSGIISMFNLCKKQLDSSYNLRVGASDGVFQ 2462

  Fly  2533 AYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKK 2597
            |...:.|:....|.|||.|.|:.|||::.||...|..:|.:.|.|.|.|.|..:.|.|:::...:
Mouse  2463 ATVPVYINTTNANKYSPEFQQNVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGE 2527

  Fly  2598 IFLIDQTTGVITSKVTFDREKKDEYVVLLKV--SDGGGKFGFASLKVIVVDVNDNVPYFLLKEYK 2660
            .|.|: .:|.||:....|||...|.|:.:|:  .|||||..|.::|:|:.|.|||.|.|....|.
Mouse  2528 RFFIN-PSGQITTLQKLDRENSTERVIAIKIMARDGGGKVAFCTVKIILTDENDNAPQFKASGYT 2591

  Fly  2661 MVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYG 2725
            :.:.:.|..:..|:.|.|.|.|...|..|.:.:  .|.:...:::||:|..||.:..|.......
Mouse  2592 VSIPSNVSRDSPIIQVLAYDADEGRNADVTYSV--DSTEDLAEEIIEVNPTTGVVKVKESLVGLE 2654

  Fly  2726 VNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGN 2790
            ..:..|.::|.|.|.|.:.|.|||.::::..:..:|.|.:........|..|.|:.:..:..:
Mouse  2655 NKAVDFNIKAQDGGPPHWDSLVPVRLQVVPNEIPLPKFSEPLYTFSASEDLPEGSEIGSVKAV-- 2717

  Fly  2791 YTFKFSIAADQDHFMIS-------------------DSGELILQQTLDREQQESHNLIVVA---- 2832
                    |.||..:.|                   |:|.|.:::.:|.|..:.:.:.::|
Mouse  2718 --------AAQDPIIYSLVQGTTPESNSDDVFSLDQDTGVLKVKKAMDHESTKWYQIDLMAHCPH 2774

  Fly  2833 -ETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIR 2896
             :|..|    :...|.|.|.|.|||.|.|:...|.|.:.||.....::::|:|.|.|||.:|.:.
Mouse  2775 EDTDLV----SLVSVNIQVEDVNDNRPVFEADPYKAFLTENMPGGTTVIQVTANDQDTGSDGQVS 2835

  Fly  2897 YYLESDT-ENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHP-KHDAKVPVTIKIVD 2959
            |.|..:. .||..:|.:|..|||||.|..||.|.|..|.|.|:|.|:|.. :..::..|.:.|.|
Mouse  2836 YRLSVEPGSNIHQLFAVDSESGWITTLQELDCETQQTYRFYVVAFDHGQTIQLSSQALVEVSITD 2900

  Fly  2960 YNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQ--EMDFFIVSGDKQAQF---QIGKS 3019
            .|||.|.|.......||.||..||.::..|..:|.||.:|  ::..:|..||...||   |:|..
Mouse  2901 ENDNPPRFASEDYRGSVVENNEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFSISQVGDE 2965

  Fly  3020 GELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGT 3084
            ..:...|.||||.:..|.|.|.|:||||.|...||:.|.|||||:|.|.:..|.....|.::.|.
Mouse  2966 WRITSRKTLDREHIAKYLLRITASDGKFQASVPVEVFVLDINDNSPQCSQLLYTGKVREDVTPGH 3030

  Fly  3085 TLVEVKAIDFDF--QSKLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDF 3147
            .:::|.|||.|.  .:::.:.|.|.||.:|.:...:|.|...|.||||....|.|||...||..
Mouse  3031 FILKVSAIDVDMDTNAQITYSLHGPGAQEFKLDPHTGELTTLSVLDRERKDVYNLVAKATDGGG- 3094

  Fly  3148 TQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGEN 3212
             |.|.:|:.:.:.|:|||.|.|..:...|:|.::..:.|.:..|.|.|.|.|||.|:.|||....
Mouse  3095 -QSCQAEVTLHIEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGVNAQVVYSLTDSA 3158

  Fly  3213 HDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVP-KLHSIATVAVNILDINDNPPEFSMR 3276
            ...|.|..::|:|||.|.|...:.|...|||:|.|.|.| .|.::.||.|:|:.:.|..|.|...
Mouse  3159 DGQFSIDATSGVIRLEKPLQVRSSSAVELTVRASDLGTPIPLSTLGTVTVSIVGLEDYLPIFLNS 3223

  Fly  3277 QYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMS 3341
            ::|.::.|:|....||  :|..::....:....|.|..|||||||::|:.||.|.:|.:||:|.:
Mouse  3224 EHSTQVPEDALIDMEV--LYLATLTRPGSEKTGYHITGGNEQGKFRLDAHTGILYVNGSLDFETN 3286

  Fly  3342 KFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDED 3406
            ..|||:|:.....:..||:...:.|::.|:|::.|.|..:||.:.|.|:..||..||.|.|:|:|
Mouse  3287 PKYFLSIECSRKSSSSLSDVTTIVINVTDVNEHHPRFTHDLYTVRVLENAIVGDVILTVSASDDD 3351

  Fly  3407 SDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPINI 3471
            ..||.::||::..|:.:|.|:||||.|.:.|::.||.|....|:|.|:|.|.|.|.......:.:
Mouse  3352 GPVNSVITYSLVGGNQLGHFTIDPKKGKLQVAKALDWEQTPSYSLRIRATDSGQPPLHEDTEVAV 3416

  Fly  3472 NILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQ 3536
            .::|.|||.|.|...|||..:|||..:|...|...:.|.|...|..||.|.|..||.|.:||:..
Mouse  3417 EVVDVNDNPPRFFQLNYSTAVQENSPIGIKVLQLILDDPDSPQNGPPYFFRITEGNTGSVFRVTP 3481

  Fly  3537 DGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDD 3601
            ||.|.||...:...|:.:.:.:.|.|:|.|||.|...|.|.|.|:|:|||...|||:.|...|::
Mouse  3482 DGWLVTAGSLSRRAQEWYQLHIEVSDSGLPPLSSSTLVRVHITEQSRYPPSTLPLEIFITKGEEE 3546

  Fly  3602 FSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVS 3666
            |.|..:||:||:|:|..|.|.:||    |......|.|.:..:.|||.|...|..|.|..||:||
Mouse  3547 FQGGMVGKIHATDRDPQDTLTYSL----DREGSLGKYFTVGASDGKIIASQGLPRGRYLFNVTVS 3607

  Fly  3667 DGKFHVFSIVKINVELVTNDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILIT 3731
            ||.|...:.|.::|..:..:..:::|.:.|.:::..|.:..|.:...|.:.||:..::.::.|.:
Mouse  3608 DGTFTTTTGVHVHVWHMGQEAPQQAVWLGFHQLTPEELVSDHWRNLQRFLSNILDIKRANIHLAS 3672

  Fly  3732 LQSDYQKASQHAVGNRRARSIDSDLNVVFAVRKQQIIPDSDEFFTSDEIRQTLIDKKNEIENETN 3796
            ||               ...:.:.::|:.|....     |...:...|:...:.....|:|:...
Mouse  3673 LQ---------------PAEVTAGVDVLLAFEGH-----SGTSYDLQELASAIAHSAKEMEHSVG 3717

  Fly  3797 LVVEDVLPST-CQSNKNDCVHGECKQILQILKNNVTTTFTDVISFAAPSYIPVNTCVCRPGFDGK 3860
            :.:...||.. ||.                                             |....:
Mouse  3718 IQMRSALPVVPCQG---------------------------------------------PSCQDQ 3737

  Fly  3861 HCKETVNACSTDPCSPQRICMPSGSALGYQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFG 3925
            .|:|||   |.:|    |: .||.|......:.|:...|..|          ||:   .|...|.
Mouse  3738 TCQETV---SLEP----RV-GPSYSTARLSILTPRHHLGKNC----------SCN---GTTWRFS 3781

  Fly  3926 GKSYAHYKINKVKAKFTLE-NGFSYSLQIRTVQQTGTLLYASGKVDYNILEIING--AVQYRFDL 3987
            |:||..|:        .|| ..:.....::|:|....|::.:.....: |::.||  .::||..
Mouse  3782 GQSYMRYR--------PLEAQNWQIHFYLKTLQPWALLMFTNETASIS-LKLANGFLHLEYRCP- 3836

  Fly  3988 GSGEGVISVSSINISDGEWHQISLERSLNSAKVMVD----NKHVSHGSAPGVNGILNIQSNDIFV 4048
            |...|.:| |...::||:||.:.||....|..::||    ...|......|:.     ....:.:
Mouse  3837 GGFYGNLS-SHRPVNDGQWHSMLLEERDTSVHLLVDITDNTSLVIPEECQGLR-----TERHLLL 3895

  Fly  4049 GAEVRPHPSIIGYEDIQRGFIGCMANIKIAKESLPLY-----ISGGSTIAALKRFTNVEFKCDPS 4108
            |..|..:||    .::..||.||:..:.:..|.|.|.     ::|.....||.:.      |.|.
Mouse  3896 GGLVPSNPS----SNVSLGFEGCLDAVVVNSERLELLGHRKKMAGYLETWALSQC------CWPG 3950

  Fly  4109 NVLVRLGICGSQPCANSGICKELDTDVFECACQPRYSGKHCEIDLDPCSSGPCLFGGRCDYHGPN 4173
            ..      |...||.|.|.|.......:.|.|.|.:||::||:..:.|:|.||..||.| ...|.
Mouse  3951 TT------CSQNPCLNGGSCSPALGSGYLCRCPPLFSGRNCELGRENCTSAPCQEGGTC-VSSPE 4008

  Fly  4174 NYSCTCPIHLSGKRCEYGKFCTPNPCKNGGICEEGDGISHCMCRGYTGPTCEIDVDECENQPCGN 4238
            ..||:|                |:|                    |||..||::...|      :
Mouse  4009 GTSCSC----------------PHP--------------------YTGDRCEMEARGC------S 4031

  Fly  4239 GATCINEPGSFRCICPSYLTGASCGDPLYSNSISTKLKNFSIEHISGIISGVAVVLVIISCVLCC 4303
            |..|:..|                         ..|..::..:....||  ||:.|:||:.|...
Mouse  4032 GGHCLITP-------------------------EIKRGDWGQQEFLVII--VALPLLIIATVGLL 4069

  Fly  4304 VVLKRSSSSKRRNRLEKDKNKSSYKEANLNSLVDKDNYCKPNVKLSNL------EVNQRPISYTA 4362
            :..:|..|.|.....:.|.         |...:..|....|.::|..|      ::||...|.|:
Mouse  4070 LYCRRCKSHKPVAMEDPDL---------LARSIGVDTQASPAIELDPLNAGSCNDLNQLEPSKTS 4125

  Fly  4363 VPND 4366
            |||:
Mouse  4126 VPNE 4129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kug	NP_001027138.2	Cadherin_repeat	66..178	CDD:206637	46/117 (39%)
		Cadherin_repeat	187..285	CDD:206637	39/97 (40%)
		E_set	309..390	CDD:298831	20/87 (23%)
		Cadherin_repeat	404..503	CDD:206637	24/100 (24%)
		Cadherin_repeat	513..609	CDD:206637	42/95 (44%)
		Cadherin_repeat	622..708	CDD:206637	25/88 (28%)
		Cadherin_repeat	776..873	CDD:206637	41/96 (43%)
		Cadherin_repeat	883..976	CDD:206637	31/96 (32%)
		Cadherin_repeat	984..1082	CDD:206637	34/98 (35%)
		Cadherin_repeat	1092..1189	CDD:206637	45/97 (46%)
		Cadherin_repeat	1197..1295	CDD:206637	43/97 (44%)
		Cadherin_repeat	1303..1386	CDD:206637	25/84 (30%)
		Cadherin_repeat	1413..1502	CDD:206637	27/89 (30%)
		Cadherin_repeat	1510..1608	CDD:206637	34/98 (35%)
		Cadherin_repeat	1621..1713	CDD:206637	36/91 (40%)
		Cadherin_repeat	1724..1811	CDD:206637	28/86 (33%)
		Cadherin_repeat	1819..1927	CDD:206637	36/107 (34%)
		Cadherin_repeat	1948..2030	CDD:206637	25/87 (29%)
		Cadherin_repeat	2037..2136	CDD:206637	35/100 (35%)
		Cadherin_repeat	2144..2235	CDD:206637	30/94 (32%)
		Cadherin_repeat	2246..2336	CDD:206637	32/91 (35%)
		Cadherin_repeat	2345..2445	CDD:206637	30/99 (30%)
		Cadherin_repeat	2453..2545	CDD:206637	33/91 (36%)
		Cadherin_repeat	2555..>2633	CDD:206637	27/79 (34%)
		Cadherin_repeat	2658..2759	CDD:206637	25/100 (25%)
		Cadherin_repeat	2774..2856	CDD:206637	20/105 (19%)
		Cadherin_repeat	2865..2963	CDD:206637	37/99 (37%)
		Cadherin_repeat	2974..3063	CDD:206637	38/93 (41%)
		Cadherin_repeat	3072..3165	CDD:206637	31/94 (33%)
		Cadherin_repeat	3173..3269	CDD:206637	35/96 (36%)
		Cadherin_repeat	3277..3374	CDD:206637	32/96 (33%)
		Cadherin_repeat	3383..3479	CDD:206637	36/95 (38%)
		Cadherin_repeat	3488..3579	CDD:206637	34/90 (38%)
		Cadherin_repeat	3590..3681	CDD:206637	35/90 (39%)
		EGF_CA	3866..3903	CDD:238011	9/36 (25%)
		Laminin_G_2	3953..4077	CDD:280389	31/129 (24%)
		EGF_CA	<4121..4150	CDD:238011	10/28 (36%)
		EGF_CA	4152..4189	CDD:238011	11/36 (31%)
		EGF_CA	4195..4225	CDD:238011	5/29 (17%)
		EGF_CA	4227..4262	CDD:214542	4/34 (12%)
Fat2	NP_001025159.1	Cadherin_repeat	38..143	CDD:206637	46/116 (40%)
		Cadherin_repeat	152..249	CDD:206637	39/96 (41%)
		Cadherin_repeat	366..454	CDD:206637	24/100 (24%)
		Cadherin_repeat	462..560	CDD:206637	42/97 (43%)
		Cadherin_repeat	570..661	CDD:206637	25/91 (27%)
		Cadherin_repeat	719..815	CDD:206637	40/95 (42%)
		Cadherin_repeat	825..921	CDD:206637	31/97 (32%)
		Cadherin_repeat	931..1026	CDD:206637	34/96 (35%)
		Cadherin_repeat	1036..1133	CDD:206637	45/97 (46%)
		Cadherin_repeat	1141..1238	CDD:206637	43/97 (44%)
		Cadherin_repeat	1247..1335	CDD:206637	26/88 (30%)
		Cadherin_repeat	1353..1444	CDD:206637	27/92 (29%)
		Cadherin_repeat	1452..1551	CDD:206637	34/98 (35%)
		Cadherin_repeat	1560..1650	CDD:206637	34/89 (38%)
		Cadherin_repeat	1664..1754	CDD:206637	28/89 (31%)
		Cadherin_repeat	1762..1867	CDD:206637	36/107 (34%)
		Cadherin	1883..1959	CDD:356102	24/86 (28%)
		Cadherin_repeat	1972..2066	CDD:206637	35/100 (35%)
		Cadherin_repeat	2074..2163	CDD:206637	29/92 (32%)
		Cadherin_repeat	2176..2268	CDD:206637	33/92 (36%)
		Cadherin_repeat	2276..2375	CDD:206637	30/99 (30%)
		Cadherin_repeat	2383..2475	CDD:206637	33/91 (36%)
		Cadherin_repeat	2485..2581	CDD:206637	35/96 (36%)
		Cadherin_repeat	2590..2683	CDD:206637	25/94 (27%)
		Cadherin_repeat	2697..2795	CDD:206637	20/111 (18%)
		Cadherin_repeat	2803..2904	CDD:206637	37/100 (37%)
		Cadherin_repeat	2913..3009	CDD:206637	38/95 (40%)
		Cadherin_repeat	3018..3111	CDD:206637	31/94 (33%)
		Cadherin_repeat	3122..3211	CDD:206637	34/88 (39%)
		Cadherin_repeat	3226..3319	CDD:206637	32/94 (34%)
		Cadherin_repeat	3328..3424	CDD:206637	36/95 (38%)
		Cadherin_repeat	3433..3524	CDD:206637	34/90 (38%)
		Cadherin_repeat	3544..3621	CDD:206637	31/80 (39%)
		Laminin_G_2	3802..3920	CDD:366983	31/129 (24%)
		EGF_CA	3953..3986	CDD:238011	11/32 (34%)
		EGF	3992..4022	CDD:333761	16/66 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	4313..4340
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I6759
eggNOG	1	0.900	-	-		E2759_KOG1219
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	2767	1.000	Inparanoid score	I23
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49381
OrthoDB	1	1.010	-	-		D12779at2759
OrthoFinder	1	1.000	-	-		FOG0001298
OrthoInspector	1	1.000	-	-		otm43591
orthoMCL	1	0.900	-	-		OOG6_100175
Panther	1	1.100	-	-	O	PTHR24026
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X900
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840