|
Fly 2338 YPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLY 2402
:|:.....|...:|||.:.||.:|::.|.|.|:|...:|.|.:.::....:.|||.||...|.:.
Human 322 HPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQSGLIR 386
Fly 2403 LKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQF 2467
....||.|.::.|::.|..:|||||.||:.:.|.:||.|.||
Human 387 TAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRND----------------------- 428
Fly 2468 VALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHT 2532
Human 429 ----------------------------------------------------------------- 428
Fly 2533 AYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKK 2597
:||:|:|:.|...:.||:..|:.|:.::|:|||....|||.|..|.....:
Human 429 --------------HSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAAR 479
Fly 2598 -----IFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKFGFAS----LKVIVVDVNDNVPY 2653
.|.||..:|:|::....|||..:.|.::::.||.|.:.|..| :.:.|:|.|||.|.
Human 480 AAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQ 544
Fly 2654 FLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFK 2718
|..|.|...|...|..:..:|.|.|.|.|...||.||:.|:..:: :....|:..||:|...
Human 545 FSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNIISGNS----RGHFAIDSLTGEIQVV 605
Fly 2719 SKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLT 2783
:..:......|...:||.|.|.| |:|
Human 606 APLDFEAEREYALRIRAQDAGRP------PLS--------------------------------- 631
Fly 2784 KLHMIGNYTFKFSIAADQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLI 2848
|.| .:|: |
Human 632 ------NNT---GLAS------------------------------------------------I 639
Fly 2849 DVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLES---DTENIQNIF 2910
.|.|.||:.|.|.:|.:..||.||:....|::.:.|.|||.|.|..:.|.|.. ||. |
Human 640 QVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTP-----F 699
Fly 2911 DIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLS 2975
.|:..:||:::...||||....|.|.|.|.|:|.|...|...||:.::|.|||.|
Human 700 VINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRP---------- 754
Fly 2976 VFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQIGKSGELFIAKPLDREQLMFYNLSI 3040
Human 755 ----------------------------------------------------------------- 754
Fly 3041 IATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQSKLRFYLS 3105
:||.| .||:..||..::||::|.|.|:|.|..|.:.:.::
Human 755 -----EFTMK--------------------EYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQIT 794
Fly 3106 GKGA-DDFSIGKESGI--LKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMP 3167
|... :.|:|..:.|: :.:|..||.:....:|||....| :.....|:..|.|| |.|.:.|
Human 795 GGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASD-RALHDHCYVHINIT--DANTHRP 856
Fly 3168 IFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLD 3232
:|..|.|.|||.||..:.:.|..:.|.|.|.|.|.:|.|.|
Human 857 VFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLL------------------------ 897
Fly 3233 RETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYA 3297
.||.|:
Human 898 ----------------------------------EDNLPQ------------------------- 903
Fly 3298 TSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNA 3362
|::|:.:|.:.|.|.||||....|.|.|.|.|.|.|..::..
Human 904 -----------------------FRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKADTT 945
Fly 3363 YVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERG-DNIGQF 3426
||.:.:.|:|||:|.|:.:.|...|:||....:.:|.:.|||.|:..||.|.|..:.| |..|.|
Human 946 YVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDF 1010
Fly 3427 SIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVV 3491
:|:|.:|.:...|.||||.:|.|.|...|.|:|.|.....|.|.:.:.|.|||||:|.:..:.|.
Human 1011 TIEPTSGIVRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVR 1075
Fly 3492 LQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLE-QDGSLRTASRFNHNLQDEFV 3555
::||.::|.|.......|.||.|| ....:.|..||...||::: ..|.|......::..:.|:|
Human 1076 VKENSIVGSVVAQITAVDPDEGPN-AHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYV 1139
Fly 3556 IQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSF----EDDFSGAFIGKVHASDQD 3616
|.|:. .:.||.|.|.|.|::::::...|::...::..|:: .|.|....||::.|.|.|
Human 1140 IVVQA---TSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPD 1201
Fly 3617 KYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIG---LYKLNVSVSDGKFHVFSIVKI 3678
..|.|.:|...| ...:|..::..:|::.....||.. :..:.|:|:||...|.:...:
Human 1202 VSDHLFYSFERG-----NELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVL 1261
Fly 3679 NVELVTNDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHA 3743
.|.::|.::|..|:.:|...:....||......|:..:..::....:||.:..:|:|..
Human 1262 RVVIITEELLANSLTVRLENMWQERFLSPLLGRFLEGVAAVLATPAEDVFIFNIQNDTD------ 1320
Fly 3744 VGNRRARSIDSDLNVVFAVRKQQIIP------DSDEFFTSDEIRQTLIDKKNEIENETNLVVEDV 3802
||. :.|||.|:. :.| .:..:|:|:|:::.|..::..:...:.| ||
Human 1321 VGG-------TVLNVSFSA----LAPRGAGAGAAGPWFSSEELQEQLYVRRAALAARSLL---DV 1371
Fly 3803 LPSTCQSNKNDCVHGECKQILQ---ILKNNVTTTFTDVISFAAPSYIPVN-----TCVCRPGFDG 3859
|| .:.|.|:...|:..:: :|:.:.:..| ::.|:..:.|:. .|.|.|||.|
Human 1372 LP----FDDNVCLREPCENYMKCVSVLRFDSSAPF---LASASTLFRPIQPIAGLRCRCPPGFTG 1429
Fly 3860 KHCKETVNACSTDPCSPQRICMPSGSALGYQCVCPKGFSGTYCE-------------RKSSKCSN 3911
..|:..::.|.::||.....|..... ||.|||...|:|..|| |....|::
Human 1430 DFCETELDLCYSNPCRNGGACARREG--GYTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCTD 1492
Fly 3912 E-------SCDMG--------LFTAVSFGGKSYAHYKINKVKAKFTLENGFSYSLQIRTVQQTGT 3961
. .|..| ...|.||...|:..::..:.:...|| ||...||||:|.
Human 1493 APNGGFRCQCPAGGAFEGPRCEVAARSFPPSSFVMFRGLRQRFHLTL------SLSFATVQQSGL 1551
Fly 3962 LLY---ASGKVDYNILEIINGAVQYRFDLGSGEGVISVS-SINISDGEWHQISLERSLNSAKVMV 4022
|.| .:.|.|:..||::.|.|:..:..|....|:|.: ...:|||:||.:.| |..| |...
Human 1552 LFYNGRLNEKHDFLALELVAGQVRLTYSTGESNTVVSPTVPGGLSDGQWHTVHL-RYYN--KPRT 1613
Fly 4023 DNKHVSHGSAPGVNGILNIQSNDIFV----GAEVRPH-------------------PSIIG---- 4060
|....:.|.:.....:|::...|:.| |||:..: |.::|
Human 1614 DALGGAQGPSKDKVAVLSVDDCDVAVALQFGAEIGNYSCAAAGVQTSSKKSLDLTGPLLLGGVPN 1678
Fly 4061 ----YEDIQRGFIGCMANIKI--AKESLPLYISGGSTIAALKRFTNVEFKCDPSNVLVRLGICGS 4119
:....:.|||||.::.| .:..:..:::...|:|..: .:|..|.|
Human 1679 LPENFPVSHKDFIGCMRDLHIDGRRVDMAAFVANNGTMAGCQ---------------AKLHFCDS 1728
Fly 4120 QPCANSGICKELDTDVFECACQPRYSGKHCEID-------------------------------- 4152
.||.|||.|.| ....|.|.|...:.||.|::.
Human 1729 GPCKNSGFCSE-RWGSFSCDCPVGFGGKDCQLTMAHPHHFRGNGTLSWNFGSDMAVSVPWYLGLA 1792
Fly 4153 ---------LDPCSSGP-----CLF---------------------------------------- 4163
|....:|| |..
Human 1793 FRTRATQGVLMQVQAGPHSTLLCQLDRGLLSVTVTRGSGRASHLLLDQVTVSDGRWHDLRLELQE 1857
Fly 4164 --GGRCDYHG---------------------------------PNNYSCTCPIHLSG-------- 4185
|||..:|. |...:...|..|.|
Human 1858 EPGGRRGHHVLMVSLDFSLFQDTMAVGSELQGLKVKQLHVGGLPPGSAEEAPQGLVGCIQGVWLG 1922
Fly 4186 -------------------KRCEYGKFCTPNPCKNGGICEEGDGISHCMCR-GYTGPTCEIDVDE 4230
..|.....|...||.....|.:......|.|: ||.||.| ||.
Human 1923 STPSGSPALLPPSHRVNAEPGCVVTNACASGPCPPHADCRDLWQTFSCTCQPGYYGPGC---VDA 1984
Fly 4231 CENQPCGNGATCINEPGS---FRCICPSYLTGASC 4262
|...||.|..:|.:.||: :.|.|.....|..|
Human 1985 CLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHC 2019
| 
