DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kug and Fat3

DIOPT Version :9

Sequence 1:	NP_001027138.2	Gene:	kug / 40191	FlyBaseID:	FBgn0261574	Length:	4699	Species:	Drosophila melanogaster
Sequence 2:	XP_038936706.1	Gene:	Fat3 / 191571	RGDID:	620657	Length:	4610	Species:	Rattus norvegicus

Alignment Length:	4794	Identity:	1729/4794 - (36%)
Similarity:	2582/4794 - (53%)	Gaps:	417/4794 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 YRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYRIISGDKEKLFKAEEKLVGDFA 124
            :.|:|::||.|:.|||..:||...  ..|:....:.|:.::||||:|||:|..|||||.::.||.
  Rat    40 FHFTHALYNATVYENSAARTYVNS--QSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFC 102

  Fly   125 FLAIRTR-TNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQY 188
            ||.|||: .|:.:||||..:.|::.:|..|...|     .|....::|:|||.|||.|||.||.|
  Rat   103 FLRIRTKGGNSAILNREIQDNYLLIIKGSVRGED-----LEAWTKVNIQVLDMNDLRPLFSPTTY 162

  Fly   189 TVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFE 253
            :|.|.|.||...|:.:|||.|||:|.|||.||......:.|::|||:|.|:|..:|.|.|.:.::
  Rat   163 SVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYD 227

  Fly   254 LTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDT 318
            |.::|.|||..:...|..:|..|:.:.::::|.:||.|...|.:..:....| .|.:|.|:|.|.
  Rat   228 LEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPIIHVVTHTPFSLDKEP-TYAVVTVDDLDE 291

  Fly   319 GINGNIGRLEIVDGNP-DGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFA 382
            |.||.|..:.||||:| :..||.|..:..:||.::..:........:.||||:.|:|.|:|::|:
  Rat   292 GANGEIESVSIVDGDPLEQFFLAKEGKWMNEYKVKERRQVDWESFSYGYNLTIQAKDKGSPQKFS 356

  Fly   383 -YKSVPIQIKPESKNIPI-FTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEG 445
             .|:|.| ..|...:.|| |.:::|::||.|.:|..:.|..:||:...|.    |...::.|.:.
  Rat   357 ELKTVHI-ANPRRDSTPIKFEKDVYDISISEFSPPGVMVAIVKVNPEPLD----VEYTLLPGKDA 416

  Fly   446 DEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENV 510
            :.|:|||.||::.||:.|:..||..|.|.||       .....:.|:|.|.::|.||:.|.|:..
  Rat   417 EYFKINPRSGLIVTAQPLNTVKKEVYKLEVS-------DKEGDAKAQVTIGIEDANDHTPEFQET 474

  Fly   511 NKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMK 575
            .....:||:...|:.|:.::|.|:|.|||.||:||||:||.:||.|:.|:|::.||..||||:..
  Rat   475 LYETFVNESVPVGTNVLTVSASDKDKGENGYITYSIASLNLLPFAINQFTGVISTTEELDFESSP 539

  Fly   576 RNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDF 640
            ..|..|:||||||.|||.::|:.::|.|.::|||.|.||:|.|.|.::...|:|..:...||||.
  Rat   540 ETYRFIVRASDWGSPYRHESEVNVTIRVGNVNDNSPLFEKVACQGVISYDFPVGGHITAISAIDI 604

  Fly   641 DAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRI------LKVSATDGTHFSDDLI 699
            |..:::.|::..|||.|.|.|:|.||.|    .|||:.:.:.|      |:::||||.:|:|.:.
  Rat   605 DELELVKYKIISGNELGFFYLNPDSGVL----QLKKSLMNSGIKNGNFALRITATDGENFADPMA 665

  Fly   700 INVHLMPEDLGGDSSILHG---FGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPS 761
            ||:           |:|||   ..||.||||.||::|||.|.:..|.|.|......|.|.
  Rat   666 INI-----------SVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNQEDGFLDF----- 714

  Fly   762 RYGQNVHRPEF-VNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPD 825
             |..|...|.| .:||.::::.|::.:|..:..|:|.|.|.|:|||::|.||||:.||.|.||.:
  Rat   715 -YSINRQGPHFDKSFPSDVAVKENMPVGTNILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDME 778

  Fly   826 RGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESA 890
            .|:|:::..:|||..:.||||||:||||.|.||:.::|.:.:.|.|||.||..:...:..:.||:
  Rat   779 TGQLKVLMPMDREHTDLYVLNITIYDLGKPQKSSWRLLTVNVEDANDNSPVFLQDSYSVSILESS 843

  Fly   891 RIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKD- 954
            .|||.:..:.|.|.|.|.|.:|||::..:...|.:|::||.:.:...||||.:.||:|.|.|:|
  Rat   844 SIGTEIIQVEARDKDLGSNGEVTYSVLTDTHQFVINSSTGIVYIADQLDRESKANYSLKIEARDK 908

  Fly   955 --GGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQF 1017
              .|..:.|...| .:.:|||||.:|.|....|..||.||||.|||:|.:|..|.|:|...::::
  Rat   909 AESGQQLFSVVTL-KIFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETQDPDLGLGGQVRY 972

  Fly  1018 SLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDP-SLTSDMSIVIMIIDVNE 1081
            ||..:....  |.|||.:||||....||||.:|.:||.|.|.|.|.| ||:|...:.:.::||||
  Rat   973 SLVNDYNGR--FEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSISFVEVEVVDVNE 1035

  Fly  1082 NRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQ-GSI 1145
            |...|.|.||...|.||||...||.|:.|||.|.|: ..:.:|.|||..|.|||.|.::|: |.|
  Rat  1036 NLHTPYFPDFAVVGSVKENSRIGTSVLQVTAHDEDS-GRDGEIQYSIRDGSGLGRFNIDDESGVI 1099

  Fly  1146 TSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENV 1210
            |:...||.||...||||:.|.|..:|||.:.:||||:||:.|||.|||.:|:||..|.|.|.::|
  Rat  1100 TAADILDRETTASYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDV 1164

  Fly  1211 EIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNG 1275
            .:|.::|.|||....:.:||.|.|||...:|.|:.|||:|.||.||||||.||||.|||.::|.|
  Rat  1165 SVIQIQAEDPDSGSNEKLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGG 1229

  Fly  1276 SPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVP--SSATVNQSIFQVHAIDSDSGENGRITYSI 1338
            |....||..:||.|||.|||.|:|.::||::::|  ......:.|::..|.|.|.|.|..|:|||
  Rat  1230 SSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSI 1294

  Fly  1339 KSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAP 1403
            ..|....||.||.:.|.:...|...:.:...:.|||.|||.|:||.|||::|..:...|.|. .|
  Rat  1295 VDGNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSP-IP 1358

  Fly  1404 LIVRKTSENVVDLTENDKPGFLVTQI---LAVDDDNDQLWYNI---------------------- 1443
            |...:...|.. :.|:||    ||:|   ::|...|..||::|
  Rat  1359 LTFDEPFYNFT-IMESDK----VTEIVGVVSVQPANTPLWFDIIGGKHAREMFYILQTACGQNCS 1418

  Fly  1444 -SNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFA 1507
             ..||.|::|...:..|.|:::|.||.|.:..||:::.|||||..|.|.:.:.|:|.|||.|:|:
  Rat  1419 TEGGNFDSSFDAEKGVGTIVIAKPLDAEQRSVYNMSVEVTDGTNVAVTQVFITVLDNNDNGPEFS 1483

  Fly  1508 KDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDF 1572
            :..|.|.|||::..::.|:|:.||||||..||.|.:|::.|..|:..||||..:|.:...:|||.
  Rat  1484 QPHYDVTISEDVPPDTEILQIEATDRDEKHKLSYTIHSSIDAISMRKFRIDPSTGVLYTAERLDH 1548

  Fly  1573 EKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAI 1637
            |...:|||.:.|:||..|.:||.|::||||.|.|||.|.||..:.::.|.||||:||.:.:|.|:
  Rat  1549 EAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSVVLQVTAL 1613

  Fly  1638 DRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIP 1702
            |:|.|.|||:.|||..||.|:.|:|:|..||||::...::..:.:::|.||..|.|:||:|:...
  Rat  1614 DKDKGENAELIYSIEAGNTGNTFKIEPVLGIITISKEPDMTAMGQFVLSVKVTDQGSPPMSATAI 1678

  Fly  1703 VHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFNIISGNINESFRINPSTG 1767
            |.|.::||:|..|||...:...|:.||:.|||.|..::|.|.|::.:.:..||||..|.|||.:|
  Rat  1679 VRISISMSDNSHPKFTHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGNINGVFTINPYSG 1743

  Fly  1768 VIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGS 1832
            ||.....:|||....:.|.::.||||..:|...:.:.::|.|||.|.|:.::|.|:|.|:|.|.|
  Rat  1744 VITTRRALDYEHTSSYQLIIQATNMAGMASNATVSVQVVDENDNPPVFLFSQYSGSLSEAAPINS 1808

  Fly  1833 YVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGYT 1897
            .|..:.:|.   |.::..|||...|.::.|.||:..||.||.:||:||||..:..||:|..|.:.
  Rat  1809 LVRSLDNSP---LVIRATDADSNQNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHEVIAHFH 1870

  Fly  1898 FDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDADND 1962
            |.|.|.|.|.|:|.:.:...|.|.|.:|||.||||.:......|.|||:..|.|.:|||.|.|::
  Rat  1871 FHVHVRDSGNPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETVLLLPTYVGVEVLKVSATDPDSE 1935

  Fly  1963 T---LRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVL 2024
            .   |.:.:::|:.:. |.::..||::|.:|    ||.:...|.|.||.|||.|.:..:|.|.|.
  Rat  1936 VPPELTYSLMEGSVDH-FLMDPNTGVLTIKN----NNLSKDHYMLIVRVSDGKFYSTAMVTIMVK 1995

  Fly  2025 SAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTT 2089
            .|:||...|.:..|..|..||:|.:..:.:||.:||.|:|.::|.||||...|.|..:||.::||
  Rat  1996 EAMDSGLHFTQSFYSTSISENSTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTT 2060

  Fly  2090 GVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDP 2154
            ||.||||.::||.|.|||...|     .::|.|...:.:::.|||||.|:||.:||||.|.:|..
  Rat  2061 GVPFDREEQELYELVVEASREL-----DHLRVARVVVRVNIEDVNDNSPVFVGLPYYAAVQVDAE 2120

  Fly  2155 KGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKLDRKSGELSIKQ--HVEGHNRNYELTVAAYD 2217
            .||:|.:|.|||.|...||||.|.|:...|. |:::..||.:.:|:  :.:..|.:|.:|:.|.|
  Rat  2121 PGTLIYRVTAIDKDKGANGEVTYVLQDDYGH-FEINPNSGNVILKEAFNSDLSNIDYGVTILAKD 2184

  Fly  2218 GAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSLIYTI--SS 2280
            |.....|:...|.:.:::::||||:|.|||.|:.||:.:.:.: :||.|.||.|:.:||.|  ..
  Rat  2185 GGTPSLSTFVELPITIVNKAMPVFDKPFYTASINEDISINTPI-LSINATSPEGQGIIYLIIDGD 2248

  Fly  2281 ESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDI 2345
            ..|.|.||::||.:.|::.||||.:|.:.:::||:|:|:|..|||.:.:.:.||||..|..:...
  Rat  2249 PFQQFNIDFDTGVLKVISPLDYEVMSVYKLTVRASDALTGARAEVTVDLLVDDVNDNPPVFDQPT 2313

  Fly  2346 YNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDYE 2410
            ||.|:.|::..||.:|::.:||.|||.|..:.|.|.. :..|:::.|:||.:.|.:.....||:|
  Rat  2314 YNTTLSESSLIGTPVLQLVSTDADSGNNNLVHYQIVQ-DTYNSTDYFHIDSSSGLILTARMLDHE 2377

  Fly  2411 QIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYD 2475
            .:::..:.|...|:|.|||||...|.|.:.|:|||.|.|.:..|.:.||..|.||.||...:|.|
  Rat  2378 LVQHCTLKVTATDNGFPSLSSEVLVQIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASD 2442

  Fly  2476 KDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYARLKIS 2540
            .|.||.|.|||.|:.||:..::.:|..:||::|.:......:....||:|||||:.|:.|::.|.
  Rat  2443 ADSSDFDRLEYSILSGNDRTSFLMDSKSGVLTLSSHRKQRMEPLYSLNVSVSDGLFTSTAQVHIR 2507

  Fly  2541 LLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTT 2605
            :|..|:|||.|.||||.|:|.||...|..:|.|:|:|||.|||..:.|.|:::..|..||||...
  Rat  2508 VLGANLYSPAFSQSTYVAEVRENAASGTKVIHVRATDGDPGTYGQVSYSIINDFAKDRFLIDSNG 2572

  Fly  2606 GVITSKVTFDREK--KDEYVVLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVE 2668
            .:||:: ..|||.  :.:..:.|:..||||:..|.:::|||||.|||.|.|:..||:..|...|.
  Rat  2573 QIITTE-RLDRENPLEGDISIYLRALDGGGRTTFCTVRVIVVDENDNAPQFMTLEYRASVRADVG 2636

  Fly  2669 ANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFV 2733
            ....:..|:|.|.|...|..:.:.:..::: .:|.|::||:...|.:|.|............|||
  Rat  2637 RGHLVTQVQALDPDDGANSRITYSLYSEAS-VSVADLLEIDPDNGWMVTKGNFNQLRNTVLSFFV 2700

  Fly  2734 RASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYTFKFSIA 2798
            :|.|.|.|..||.:||.|.::..:..:|:|.:|.....|.|.|..|:.:..|.::.|.:.:||..
  Rat  2701 KAVDGGIPVRHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTSIGSTIDTLRILPNQSVRFSTV 2765

  Fly  2799 -------ADQDHFMI-SDSGELILQQTLDREQQESHNLIVVAETSTVP-----VFFAYADVLIDV 2850
                   ..::.|:| .::|.:.|.:.||.|...:.:..|.|   |:|     :.|. .||.:.|
  Rat  2766 NGERPENNKENVFIIEQETGAIKLDKRLDHEVSPAFHFKVAA---TIPLDKVDIVFT-VDVDVKV 2826

  Fly  2851 RDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDT--ENIQNIFDID 2913
            .|.|||.|.|:.:.|...:.|.......|.:|.|.|.|.|.||.:.|.|.||:  |.:...|:||
  Rat  2827 LDLNDNKPVFETSSYETIIMEGMPVGTKLAQVRAIDTDWGANGQVTYSLHSDSHLEKVMEAFNID 2891

  Fly  2914 IYSGWITLLTSLDREVQSEYNFKVIAADNGHP-KHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVF 2977
            ..:|||:.|..||.|....::|.|:|:|.|.. ...:...|::|:.|.|||||||...:...:|.
  Rat  2892 SNTGWISTLKDLDHETDPTFSFFVVASDLGEAFSLSSMALVSVKVTDINDNAPVFAHEVYRGNVK 2956

  Fly  2978 ENALPGTVLINLLLIDPDIE--KQEMDFFIVSGDKQAQFQIG---KSGELFIAKPLDREQLMFYN 3037
            |:..||.|:..|..:|.|..  .:::.:.|..|:.:.:|.:|   ...::::.:|||||:...|.
  Rat  2957 ESDPPGEVVAVLSTLDKDTSNINRQVSYHITGGNPRGRFALGMVQSEWKVYVKRPLDREEQDIYF 3021

  Fly  3038 LSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQSK--L 3100
            |:|.|:||.|..:|.||:.|.|:|||:|.|.:..|..|..|.|.....:::|.|.|.|..|.  :
  Rat  3022 LNITASDGLFVTQAMVEVTVSDVNDNSPVCDQVAYSASLPEDIPSNKIILKVSAKDADIGSNGDI 3086

  Fly  3101 RFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDN 3165
            |:.|.|.|..||.:..|||.||..:.||||..|.|.|:|...||..  :.|.|.:::.:.|:|||
  Rat  3087 RYSLYGSGNSDFFLDPESGELKTLALLDRERVPVYNLIARATDGGG--RFCSSTVLLLLEDVNDN 3149

  Fly  3166 MPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKS 3230
            .|:||...|...|.|:.....|:|:|.|:|.|.|:||::.|||.......|.|..|:|:|.|.:.
  Rat  3150 PPVFSSNHYTACVYENTATKALLTRVQAVDPDVGINRKVVYSLEDSASGVFSIDSSSGVIVLEQP 3214

  Fly  3231 LDRETISLFNLTVKAEDCGV-PKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCK 3294
            ||||..|.:|::|:|.|... ..|.|:.:|.:.:||||||||.|..|.|...:.|:.:.||:|..
  Rat  3215 LDREQQSSYNISVRATDQSPGQSLSSLTSVTITVLDINDNPPVFERRDYLVTVPEDTSLGTQVLS 3279

  Fly  3295 VYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLS 3359
            |:|||.|||.||:|.|.|.||||||||:::..||.:.:...|||||.|.::|.::|.|||||.||
  Rat  3280 VFATSKDIGTNAEITYLIRSGNEQGKFRINPKTGGISVLEALDYEMCKRFYLVVEAKDGGTPALS 3344

  Fly  3360 NNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIG 3424
            ..|.|:|.:.|:|||.|.|.|::|...::||...|..::.:.|.|.||..||.:.::|..||...
  Rat  3345 TAATVSIDLTDVNDNPPRFSQDVYSAVISEDALEGDSVILLIAEDVDSKPNGQIRFSIVGGDRDN 3409

  Fly  3425 QFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYS 3489
            :|::||..|.:.|.:.||||.:|.|:|.|||.|.|.|...::..:||:|.|.|||:|:|:.:||:
  Rat  3410 EFAVDPILGLVKVKKKLDRERVSGYSLLIQAVDSGIPAMSSTTTVNIDISDVNDNSPVFTPANYT 3474

  Fly  3490 VVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQDEF 3554
            .|:|||:.:|...|...::|.|...|..|::|.|.||||...|.|:..|.||:|..|.|....|:
  Rat  3475 AVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEDEEFMLDSHGILRSAVVFRHMESPEY 3539

  Fly  3555 VIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQDKYD 3619
            ::.::..|:|.|...|..::.|::||||.:.|...|||:.|.:.||||.|..|||:||:|||.||
  Rat  3540 LLCIQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYD 3604

  Fly  3620 ELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDGKFHVFSIVKINVELVT 3684
            .|.|:|.|      :...||.::::.|||.|:..||.|.|.||||||||:|.|...|.::||.:.
  Rat  3605 VLTFALKS------EQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLV 3663

  Fly  3685 NDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHAVGNRRA 3749
            ::||:.:|.|||..:|..:|:..|...|.|.:||.:..:::|.:.|.       :.|..||.
  Rat  3664 HEMLQNTVTIRFENVSPEDFVGLHMHGFRRILRNAVLTQKQDSLRII-------SIQPVVGT--- 3718

  Fly  3750 RSIDSDLNVVFAVRKQQIIPDSDEFFTSDEIRQTLIDKKNEIENETNLVVEDVLPSTCQSNKNDC 3814
                :.|:::|||...     |.||:....:.|.|.:.:..:||..::..  :|...|..  .||
  Rat  3719 ----NQLDMLFAVEMH-----SSEFYKPAYLIQKLSNARRHLENVMHIAA--ILEKNCSG--LDC 3770

  Fly  3815 VHGECKQILQILKNNVTTTFTDVISFAAPSYIPVNTCVCRPGFDGKHCKETVNACSTDPCSPQRI 3879
            ....|:|.|.:..:.:.|..|..|||..|.:.....|.|..|.    |..:.:.|...||.....
  Rat  3771 QEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCNGGV----CPGSNDPCVEKPCPEDMQ 3831

  Fly  3880 CMPSGSALGYQ-------CVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAHYKINKV 3937
            |      :||:       |.||.|        |..:||..       |::||.|.||..|::
  Rat  3832 C------VGYEASRRPFLCQCPPG--------KLGECSGH-------TSLSFAGNSYIKYRL--- 3872

  Fly  3938 KAKFTLENGFSYSLQIRTVQQTGTLLYASGKVDYNILEIINGAVQYRFDLGSGEGVISVSSINIS 4002
             ::.:.|..|..:|::||:|..|.::|.... ...||:|:.|.:.::.|.|||.|::.:||..::
  Rat  3873 -SENSREEDFKLALRLRTLQSNGIIMYTRAN-PCMILKIVEGKLWFQLDCGSGPGILGISSRAVN 3935

  Fly  4003 DGEWHQISLERSLNSAKVMVDNKHVSHGSAPGVNGILNIQSNDIFVGAEVRPHPSIIGYED---- 4063
            ||.||.:.||.:.|...:.:|:.:|....||.....|:..| .||.||.|:. .:|....|
  Rat  3936 DGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTDS-AIFFGALVQA-DNIRSLTDTRVT 3998

  Fly  4064 -IQRGFIGCMANIKIAKESLPLYISGGSTIAALKRFTNVEFKCDPSNVLVRLGICGSQPCANSGI 4127
             :..||.||:.::.:....|||. :..|:.|.:...|.           ::||
  Rat  3999 QVLGGFQGCLDSVVLNHNELPLQ-NKRSSFAEVVGLTE-----------LKLG------------ 4039

  Fly  4128 CKELDTDVFECACQPRYSGKHCEIDLDPCSSGPCLFGGRCDYHGPNNYSCTCPIHLSGKRCEYG- 4191
                      |...|           |.|...|||.||.|.......|.|:|....:|..||..
  Rat  4040 ----------CVLYP-----------DACQRSPCLHGGSCSGLPSGGYQCSCLSQFTGTNCESEI 4083

  Fly  4192 KFCTPNPCKNGGICEEGDGISHCMCR-GYTGPTCEIDVDECENQPCGNGATCINEPGSFRCIC-P 4254
            ..|.||||:|||.|:.......|.|: |.||.|||.||||||.:.|.||.:|:|..|||.|.| |
  Rat  4084 TACFPNPCRNGGSCDPIGNTFICSCKAGLTGVTCEDDVDECEREECENGGSCVNLFGSFFCNCTP 4148

  Fly  4255 SYLTGASCG-DPLYSNSISTKLKNFSIEHISGIISGVAVVL-VIISCVLCCVVLKRSSSSKRRNR 4317
            .|: |..|| .|:...:|.........|.:.||    |||| ||.:.::..:|.::....|..:|
  Rat  4149 GYV-GQYCGLRPVVVPNIQAGHSYVGKEELIGI----AVVLFVIFTLIVLFIVFRKKVFRKNYSR 4208

  Fly  4318 LEKDKNKSSYKEANLNSLVDKDNYCKPNVKLSNL---------------EVNQRPISYTAVPNDN 4367
                .|.:..::....:|:.|.|    .:...:|               :|..||::||.....:
  Rat  4209 ----NNITLVQDPATAALLHKSN----GIPFRSLRAGDGRNVYQEVGPPQVPVRPMAYTPCFQSD 4265

  Fly  4368 LVLSNRNFVNNLDILRSYGSAGDELENVPFEYQKVNRNKQHV----------NINSCHSTDADNA 4422
               |..|....||.|   |....||.....|..::...::.|          .::.|.| |.|:.
  Rat  4266 ---SRSNLDKGLDAL---GGEPQELSTFHPESPRILTARRGVVVCSVAPNLPAVSPCRS-DCDSI 4323

  Fly  4423 YKQEWCEQMHLRTFSENKLNNELKRDFGPSVSRFST---GKLIQVEMPNVCHSSSA--------- 4475
            .|..|      .|.||||    ...|.| .|:.|:.   |...:|:..|...|.|.
  Rat  4324 RKNGW------DTGSENK----GAEDTG-EVTCFANSNKGSNSEVQSLNSFQSDSGDDNASIVTV 4377

  Fly  4476 -----NFVD-----YSALANGQ-----YHWDCSDWVRKSHNPLPDITEVPGAEIADSSSLHSNDS 4525
                 |.||     .|.:..||     ||||.|||:..:.  |.||.|:|..|..|..::|...:
  Rat  4378 IQLVNNVVDSIENEVSVMDQGQNYNRAYHWDTSDWMPGAR--LSDIEEMPNYESQDGGAVHQGST 4440

  Fly  4526 NESKSKKAFFVHREDGDVDPTRDIAALNEDIGSEYLDSEAESCLEPFMLPRSSNQPLSRLSSFNN 4590
            .|.:|                 |......||.|||.....|..|....||    .||.
  Rat  4441 RELES-----------------DYYLGGYDIDSEYPPPHEEEFLSQDQLP----PPLP------- 4477

  Fly  4591 IENEDYKSNTVPLP--------SKVSHSCKVYLR-HPDSYLPTMHFPSETDGESSMTEGPISRME 4646
               ||:......||        ..:|..|:...| ||..|||....|.|||     ..||.|..:
  Rat  4478 ---EDFPEQYEALPPSQPTSLTGTMSPDCRRRPRFHPSQYLPPHPLPGETD-----LGGPPSSCD 4534

  Fly  4647 IKTRRTISENSEEAYLFPCTVGEIG-------SNSNISVRLCEIEDSEL 4688
            ..| ..:|.|.....:.|.....:.       |:|::|.| |..:|||:
  Rat  4535 FST-FAVSMNQGTEVMAPTDSVSLSLHNSRGTSSSDMSAR-CGFDDSEV 4581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kug	NP_001027138.2	Cadherin_repeat	66..178	CDD:206637	44/112 (39%)
		Cadherin_repeat	187..285	CDD:206637	37/97 (38%)
		E_set	309..390	CDD:298831	30/82 (37%)
		Cadherin_repeat	404..503	CDD:206637	31/98 (32%)
		Cadherin_repeat	513..609	CDD:206637	44/95 (46%)
		Cadherin_repeat	622..708	CDD:206637	31/91 (34%)
		Cadherin_repeat	776..873	CDD:206637	42/96 (44%)
		Cadherin_repeat	883..976	CDD:206637	34/95 (36%)
		Cadherin_repeat	984..1082	CDD:206637	43/98 (44%)
		Cadherin_repeat	1092..1189	CDD:206637	46/97 (47%)
		Cadherin_repeat	1197..1295	CDD:206637	49/97 (51%)
		Cadherin_repeat	1303..1386	CDD:206637	29/84 (35%)
		Cadherin_repeat	1413..1502	CDD:206637	33/114 (29%)
		Cadherin_repeat	1510..1608	CDD:206637	44/97 (45%)
		Cadherin_repeat	1621..1713	CDD:206637	40/91 (44%)
		Cadherin_repeat	1724..1811	CDD:206637	32/86 (37%)
		Cadherin_repeat	1819..1927	CDD:206637	42/107 (39%)
		Cadherin_repeat	1948..2030	CDD:206637	29/84 (35%)
		Cadherin_repeat	2037..2136	CDD:206637	40/98 (41%)
		Cadherin_repeat	2144..2235	CDD:206637	33/92 (36%)
		Cadherin_repeat	2246..2336	CDD:206637	36/91 (40%)
		Cadherin_repeat	2345..2445	CDD:206637	35/99 (35%)
		Cadherin_repeat	2453..2545	CDD:206637	35/91 (38%)
		Cadherin_repeat	2555..>2633	CDD:206637	31/79 (39%)
		Cadherin_repeat	2658..2759	CDD:206637	28/100 (28%)
		Cadherin_repeat	2774..2856	CDD:206637	24/94 (26%)
		Cadherin_repeat	2865..2963	CDD:206637	34/100 (34%)
		Cadherin_repeat	2974..3063	CDD:206637	30/93 (32%)
		Cadherin_repeat	3072..3165	CDD:206637	34/94 (36%)
		Cadherin_repeat	3173..3269	CDD:206637	37/96 (39%)
		Cadherin_repeat	3277..3374	CDD:206637	47/96 (49%)
		Cadherin_repeat	3383..3479	CDD:206637	36/95 (38%)
		Cadherin_repeat	3488..3579	CDD:206637	31/90 (34%)
		Cadherin_repeat	3590..3681	CDD:206637	44/90 (49%)
		EGF_CA	3866..3903	CDD:238011	10/43 (23%)
		Laminin_G_2	3953..4077	CDD:280389	40/128 (31%)
		EGF_CA	<4121..4150	CDD:238011	2/28 (7%)
		EGF_CA	4152..4189	CDD:238011	12/36 (33%)
		EGF_CA	4195..4225	CDD:238011	14/30 (47%)
		EGF_CA	4227..4262	CDD:214542	19/35 (54%)
Fat3	XP_038936706.1	Cadherin_repeat	47..152	CDD:206637	44/111 (40%)
		Cadherin_repeat	161..261	CDD:206637	38/99 (38%)
		CA	285..363	CDD:214520	28/77 (36%)
		Cadherin_repeat	379..467	CDD:206637	31/98 (32%)
		Cadherin_repeat	476..573	CDD:206637	44/96 (46%)
		Cadherin_repeat	591..671	CDD:206637	32/94 (34%)
		Cadherin_repeat	732..826	CDD:206637	41/93 (44%)
		Cadherin_repeat	834..930	CDD:206637	33/96 (34%)
		Cadherin_repeat	939..1022	CDD:206637	39/84 (46%)
		Cadherin_repeat	1048..1143	CDD:206637	46/95 (48%)
		Cadherin_repeat	1151..1249	CDD:206637	49/97 (51%)
		Cadherin_repeat	1257..1347	CDD:206637	32/89 (36%)
		Cadherin_repeat	1366..1478	CDD:206637	34/116 (29%)
		Cadherin_repeat	1486..1584	CDD:206637	44/97 (45%)
		Cadherin_repeat	1593..1683	CDD:206637	38/89 (43%)
		Cadherin_repeat	1698..1787	CDD:206637	32/88 (36%)
		Cadherin_repeat	1795..1901	CDD:206637	43/108 (40%)
		Cadherin_repeat	1920..1999	CDD:206637	28/83 (34%)
		Cadherin_repeat	2009..2102	CDD:206637	40/97 (41%)
		Cadherin_repeat	2110..2201	CDD:206637	33/91 (36%)
		Cadherin_repeat	2213..2305	CDD:206637	37/92 (40%)
		Cadherin_repeat	2313..2412	CDD:206637	35/99 (35%)
		Cadherin_repeat	2420..2512	CDD:206637	35/91 (38%)
		Cadherin_repeat	2522..2618	CDD:206637	40/96 (42%)
		Cadherin_repeat	2626..2721	CDD:206637	28/95 (29%)
		Cadherin_repeat	2734..2832	CDD:206637	25/101 (25%)
		Cadherin_repeat	2840..2942	CDD:206637	34/101 (34%)
		Cadherin_repeat	2950..3047	CDD:206637	30/96 (31%)
		Cadherin_repeat	3056..3149	CDD:206637	34/94 (36%)
		Cadherin_repeat	3157..3254	CDD:206637	37/96 (39%)
		Cadherin_repeat	3263..3359	CDD:206637	47/95 (49%)
		Cadherin_repeat	3367..3464	CDD:206637	36/96 (38%)
		Cadherin_repeat	3473..3564	CDD:206637	31/90 (34%)
		Cadherin_repeat	3583..3660	CDD:206637	40/82 (49%)
		Laminin_G_2	3887..4016	CDD:396680	40/131 (31%)
		EGF_CA	4045..4080	CDD:238011	12/34 (35%)
		EGF_CA	4079..4118	CDD:238011	17/38 (45%)
		EGF_CA	4120..4155	CDD:238011	19/35 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	166	1.000	Domainoid score	I3787
eggNOG	1	0.900	-	-		E2759_KOG1219
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	2759	1.000	Inparanoid score	I21
OMA	1	1.010	-	-		QHG49381
OrthoDB	1	1.010	-	-		D12779at2759
OrthoFinder	1	1.000	-	-		FOG0001298
OrthoInspector	1	1.000	-	-		otm45664
orthoMCL	1	0.900	-	-		OOG6_100175
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X900
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.740