DRSC/TRiP Functional Genomics Resources

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Protein Alignment kug and LOC108191765

DIOPT Version :9

Sequence 1:NP_001027138.2 Gene:kug / 40191 FlyBaseID:FBgn0261574 Length:4699 Species:Drosophila melanogaster
Sequence 2:XP_017214098.2 Gene:LOC108191765 / 108191765 -ID:- Length:888 Species:Danio rerio


Alignment Length:935 Identity:216/935 - (23%)
Similarity:362/935 - (38%) Gaps:281/935 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   881 LATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSD---FTVNATTGCLRLNKPLDREK 942
            :|.|.|.|...:||.|:.|:.:|.:..   .||:.::.:...   |:|...:|.:.|.:.||||.
Zfish    42 MALFSLAEDTAVGTHVYTLNGSDPEGD---PVTFGVTFDKGSKQFFSVEPKSGRVTLVEHLDREL 103

  Fly   943 QDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDE 1007
            ||.....::..||.:.|:.|   |.|.:.||||..|.|........|.||:..|..:..::|||.
Zfish   104 QDEIIASVSITDGRNKVVES---VRVFITDVNDEKPEFMNLPLRVDVPEDVASGCSIFRVQAVDR 165

  Fly  1008 DIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSI 1072
            |:|....:.:.|  ::..:.||.||.|:|.:|.:..||:|..:.|.:.|.|.|||..        
Zfish   166 DLGSGGSVSYFL--QSSPDGLFSIDGHSGVLRVRERLDFETSRTHFITVVAKDGGGK-------- 220

  Fly  1073 VIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIF 1137
                                |.||                             |.:         
Zfish   221 --------------------YHGK-----------------------------YQV--------- 227

  Fly  1138 AVNDQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNV 1202
                                               ||:...:.|.|::..|:.|:.....|:..|
Zfish   228 -----------------------------------LSSTAVITIHVQDVQDSPPVFVGTPYFGFV 257

  Fly  1203 TEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHIL 1267
            .|.||...||.|:.|.|.|......|.|:|::|: .|:|.|:|.:|.|......:...|:...:.
Zfish   258 YEVSVPGSEIFTVFAKDGDQSSPNPIHYSILNGS-DGFFSINSSSGCISLVSFPVQLRNELYELR 321

  Fly  1268 EVAISDNGSPVL--SSTSRIVVSVLDINDNSP----------EFDQRVYKVQVPSSATVNQSIFQ 1320
            ..|.......||  ||.:.:.:.|:|:|::.|          .||..:|  :.|:...:.:.: :
Zfish   322 VQAAEVGADGVLADSSITTVTIRVVDLNNHPPTFYGESGQQNHFDISMY--EHPAEGEILRGL-K 383

  Fly  1321 VHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQT 1385
            :...|||.|.|.             |||       :.:..|                        
Zfish   384 ITVNDSDQGANA-------------KFR-------LVLVGP------------------------ 404

  Fly  1386 ARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQLWYNISNGNDDN 1450
            :||..||.....|.....:||..:|  .:|.   :|..||..::|||:.|               
Zfish   405 SRVLRVVPQTVLNEAQVTVIVENSS--AIDY---EKHQFLTFKLLAVEID--------------- 449

  Fly  1451 TFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNI 1515
                                           |...|:|..::::.::|.|||.|:|:.:.|...|
Zfish   450 -------------------------------TPERFSATADIVINLLDTNDNTPKFSSEFYIARI 483

  Fly  1516 SENIEEESVIMQLHATDRDED--KKLFYHLHATQDPSSLALFRIDSISGNVIVTQ---RLDFEKT 1575
            .||....|.::.:.|||.|..  .::.|.::.    |...||.|...|| :|.||   .||.|..
Zfish   484 PENSPGGSNVVSVTATDPDSGLWGEVKYSIYG----SGADLFLIHPSSG-IIYTQPWAALDAEVK 543

  Fly  1576 AQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRD 1640
            :::..  :||.:...||.:.|::.|.|.|.|||.|||....::    ::..||:.: :::|:|.|
Zfish   544 SKYNF--YVKAEDTEGKYSLAEVFVTVLDQNDHPPEFNENFLE----KTMIIGAPV-KIQAVDED 601

  Fly  1641 SGH-NAEIQYSIITGNVGSVFEIDPTFGIITLAGNL-------NINKIQE--YMLQVKAVDLGNP 1695
            :.. |..|:|||:..:..::|:|:.:.|.|.|...:       ||::.:|  :.:.|:|.|.|:|
Zfish   602 AEEPNNLIEYSIMKADPDNIFDINTSTGEIKLKPYIKSLEIVQNISRQRECRWSVVVQARDRGSP 666

  Fly  1696 PLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQ---------VTARS--SSSIFF 1749
            ..|:...|.|.:|    :..:|           |.|:.||:.|         |.|.|  ::.:..
Zfish   667 SFSTTAVVKIDIT----EANRF-----------NGPMSTFLKQSRENPLQVLVLALSGITAMVLL 716

  Fly  1750 NIISGNI-----NESFRINPSTGVI 1769
            .::...|     .:|.||.|:..:|
Zfish   717 TVLISTIIYCRNTKSNRIMPARRII 741

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kugNP_001027138.2 Cadherin_repeat 66..178 CDD:206637
Cadherin_repeat 187..285 CDD:206637
E_set 309..390 CDD:298831
Cadherin_repeat 404..503 CDD:206637
Cadherin_repeat 513..609 CDD:206637
Cadherin_repeat 622..708 CDD:206637
Cadherin_repeat 776..873 CDD:206637
Cadherin_repeat 883..976 CDD:206637 29/95 (31%)
Cadherin_repeat 984..1082 CDD:206637 26/97 (27%)
Cadherin_repeat 1092..1189 CDD:206637 8/96 (8%)
Cadherin_repeat 1197..1295 CDD:206637 30/99 (30%)
Cadherin_repeat 1303..1386 CDD:206637 11/82 (13%)
Cadherin_repeat 1413..1502 CDD:206637 13/88 (15%)
Cadherin_repeat 1510..1608 CDD:206637 31/102 (30%)
Cadherin_repeat 1621..1713 CDD:206637 27/101 (27%)
Cadherin_repeat 1724..1811 CDD:206637 14/62 (23%)
Cadherin_repeat 1819..1927 CDD:206637
Cadherin_repeat 1948..2030 CDD:206637
Cadherin_repeat 2037..2136 CDD:206637
Cadherin_repeat 2144..2235 CDD:206637
Cadherin_repeat 2246..2336 CDD:206637
Cadherin_repeat 2345..2445 CDD:206637
Cadherin_repeat 2453..2545 CDD:206637
Cadherin_repeat 2555..>2633 CDD:206637
Cadherin_repeat 2658..2759 CDD:206637
Cadherin_repeat 2774..2856 CDD:206637
Cadherin_repeat 2865..2963 CDD:206637
Cadherin_repeat 2974..3063 CDD:206637
Cadherin_repeat 3072..3165 CDD:206637
Cadherin_repeat 3173..3269 CDD:206637
Cadherin_repeat 3277..3374 CDD:206637
Cadherin_repeat 3383..3479 CDD:206637
Cadherin_repeat 3488..3579 CDD:206637
Cadherin_repeat 3590..3681 CDD:206637
EGF_CA 3866..3903 CDD:238011
Laminin_G_2 3953..4077 CDD:280389
EGF_CA <4121..4150 CDD:238011
EGF_CA 4152..4189 CDD:238011
EGF_CA 4195..4225 CDD:238011
EGF_CA 4227..4262 CDD:214542
LOC108191765XP_017214098.2 Cadherin_repeat 45..133 CDD:206637 28/93 (30%)
Cadherin_repeat 142..243 CDD:206637 34/203 (17%)
Cadherin_repeat 252..351 CDD:206637 30/99 (30%)
Cadherin_repeat 364..470 CDD:206637 34/203 (17%)
Cadherin_repeat 479..574 CDD:206637 31/101 (31%)
Cadherin_repeat 589..682 CDD:206637 27/97 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

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