DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7668 and angptl2a

DIOPT Version :9

Sequence 1:NP_649170.1 Gene:CG7668 / 40190 FlyBaseID:FBgn0036929 Length:422 Species:Drosophila melanogaster
Sequence 2:NP_001025401.1 Gene:angptl2a / 569092 ZFINID:ZDB-GENE-080721-15 Length:525 Species:Danio rerio


Alignment Length:481 Identity:111/481 - (23%)
Similarity:182/481 - (37%) Gaps:111/481 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 NSRSSPDSSTENNSSSSDSEMEFVGTSARGMLKHKKKDERKISELTRKLAEAE------------ 64
            ||: .|::..||..:..:.|:      ..|.| ||   :|:..|..::|.|.:            
Zfish    82 NSK-EPEALLENRVNKQELEL------LNGEL-HK---QRRQIETLQQLVEVDGGVVNEVKLLRK 135

  Fly    65 ----INLKAQQEKGSILENCIKDKDDFIKTLQLSIDLVTQTKEMTIQKLQTQIMDLQSDL----- 120
                :|.:..|....:|...|:.:|:.::..||...::..|.||  |:|.::..||:...     
Zfish   136 ESRNMNARVTQLYMQLLHEIIRKRDNALEVSQLENRVLNHTSEM--QQLTSRYRDLEHKYQHLAS 198

  Fly   121 ---DLSRITIKKND---------GGNCAPAHDKVVKERKELNMENGK-------------F---- 156
               :.|.:.::..:         |....|....||..:.....::.:             |    
Zfish   199 LASNQSAVIVQLEEQCRRGGFVGGRQTRPYQPPVVPPQPAQTPQHRQPPPPPVHHSPARPFHPPT 263

  Fly   157 --REGNDQIVEIEKILNSKEAEIARLEFKIDESKLKIVQLEGAVKAKDEKIVKMTEILSEYNVNN 219
              |:.|....||:...|||....|....:.:.......:|.|..|          :.|......:
Zfish   264 YPRQNNQMTNEIQSDQNSKAMPSALPTEQSETHSFSTDKLSGPFK----------DCLQALEEGH 318

  Fly   220 KDHDEFVLL--GSSKLPSIKLVTLPDFEPFASVFEDIPSAGRGWMIIQRRIDGS---FDNATESN 279
            .:...|:|.  .::||              ..|:.|......||.:||||:|||   |.|  ...
Zfish   319 SNSGMFLLKPENTNKL--------------MQVWCDQRHDPGGWTVIQRRMDGSVNFFRN--WET 367

  Fly   280 IITGCGDLGGEFWLGLQKLHKMTTHRRMELYIQLVDFDNASAYARYDNFVIGDEKQKYKLLSLGE 344
            ...|.|::.||:||||:.::.:|.....:|.:.|.|:.....:|.|.:|.:..|...|| :.:|.
Zfish   368 YKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTLEDWSGRKTFAEYASFRLEPEADFYK-MRVGR 431

  Fly   345 YSGNAGDAFRSH----------INHIIVGNPFAMESSKWW--GTMNCNLNGK-YRNSKVELDTTD 396
            |.|||||:...|          .:....||....:...||  ...:.||||. ||.........|
Zfish   432 YHGNAGDSMTWHNGKQFTTLDRDHDAYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQD 496

  Fly   397 GIWWGNWNVGNRYPLKSCKMLIRPMP 422
            |::|..:. |..|.||...|:|||.|
Zfish   497 GVYWAEFR-GGSYSLKKVTMMIRPNP 521

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7668NP_649170.1 DUF16 146..>212 CDD:279814 12/84 (14%)
FReD 245..421 CDD:294064 59/191 (31%)
angptl2aNP_001025401.1 DUF1875 <50..>147 CDD:286100 15/75 (20%)
Fib_alpha 119..215 CDD:285864 17/97 (18%)
FReD 305..519 CDD:238040 65/241 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2579
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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