Protein Alignment CG7668 and ANGPTL4

DIOPT Version :9

• Sequence 1: NP_649170.1
• Gene: CG7668 / 40190
• FlyBaseID: FBgn0036929
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_005272541.1
• Gene: ANGPTL4 / 51129
• HGNCID: 16039
• Length: 424
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 102/460 - (22%)
• Similarity: 170/460 - (36%)
• Gaps: 113/460 - (24%)

  Fly    12 NSRSSPDSSTENNSSSSDSEMEFVGTS----ARGMLKHKKKDERKISELTRKLAEAEINLKAQQE 72
            :::..|..|.....:|.| ||..:...    .:|:.:|.::...::|.|.|:|:..  ....|..
Human    22 SAQGGPVQSKSPRFASWD-EMNVLAHGLLQLGQGLREHAERTRSQLSALERRLSAC--GSACQGT 83

  Fly    73 KGSILENCIKDKDDFIKTLQLSIDLVTQTKEMTIQKLQTQIMDLQSDLDLSRITIKKNDGGNCAP 137
            :||               ..|.:...::.....:..||||
Human    84 EGS---------------TDLPLAPESRVDPEVLHSLQTQ------------------------- 108

  Fly   138 AHDKVVKERKELNMENGKFREGNDQIVEIEKILNSKEAEIARLEFKIDESKLKIVQLEGAVKAKD 202
                       |..:|.:.::...::.:.::.|..:...|..|:.:......|.:..|.|..|:.
Human   109 -----------LKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARR 162

  Fly   203 EKIVKMTE-ILSEYNVNN-----KDHDEFVLLG--SSKLPSIKLVTLPDFEPFASVFEDIPSAGR 259
            :::.:|.: :...:||:.     :|..|...:|  .|.|..|:....|.|.....:..|     .
Human   163 KRLPEMAQPVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSD-----G 222

  Fly   260 GWMIIQRRIDGSFD-NATESNIITGCGDLGGEFWLGLQKLHKMTTHRRMELYIQLVDFDNASAYA 323
            ||.:||||.|||.| |........|.||..|||||||:|:|.:|..|...|.:||.|:|..:...
Human   223 GWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELL 287

  Fly   324 RYDNFVIGDEKQKYKLLSLGEYSGNAG----------------------------------DAFR 354
            :: :..:|.|...|.|......:|..|                                  .:..
Human   288 QF-SVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSAPSVA 351

  Fly   355 SHINHIIVGNPFAMESSKWWGT-MNCNLNGKYRNS--KVELDTTDGIWWGNWNVGNRYPLKSCKM 416
            ...:|  |.:|.......|:|| .:.||||:|..|  :.......||:|..|. |..|||::..|
Human   352 QRPDH--VPSPLTPAGGWWFGTCSHSNLNGQYFRSIPQQRQKLKKGIFWKTWR-GRYYPLQATTM 413

  Fly   417 LIRPM 421
            ||:||
Human   414 LIQPM 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814	10/66 (15%)
		FReD	245..421	CDD:294064	60/213 (28%)
ANGPTL4	XP_005272541.1	FReD	183..418	CDD:238040	68/243 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000