DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7668 and Tnn

DIOPT Version :9

Sequence 1:	NP_649170.1	Gene:	CG7668 / 40190	FlyBaseID:	FBgn0036929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_808507.2	Gene:	Tnn / 329278	MGIID:	2665790	Length:	1560	Species:	Mus musculus

Alignment Length:	187	Identity:	69/187 - (36%)
Similarity:	94/187 - (50%)	Gaps:	24/187 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 VFEDIPSAGRGWMIIQRRIDGSFDNATE-SNIITGCGDLGGEFWLGLQKLHKMT--THRRMELYI 311
            |:.|:.:.|.||::.|||..|..|.... .:.:.|.||...||||||.|||.:|  |..|.|:..
Mouse  1360 VYCDMDTDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTTTRYEVRA 1424

  Fly   312 QLVDFDNASAYARYDNFVIGDEKQKYKLLSLGEYSGNAGDAFRSH----------INHIIVGNPF 366
            .|..| |.||||.||.|.:...|::|| ||:|:|.|.||||...|          .|.|.:.|..
Mouse  1425 DLQTF-NESAYAVYDFFQVASSKERYK-LSVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCA 1487

  Fly   367 AMESSKWWGTMNCNL---NGKYRNSKVELDTTDGIWWGNWNVGNRYPLKSCKMLIRP 420
            ......|| ..||:|   ||||..:|    .::|:.|..|. |:.:.:...::.|||
Mouse  1488 LTHHGGWW-YKNCHLANPNGKYGETK----HSEGVNWEPWK-GHEFSIPYVELKIRP 1538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814
CG7668	NP_649170.1	FReD	245..421	CDD:294064	69/187 (37%)
Tnn	NP_808507.2	EGF_2	<142..166	CDD:285248
		EGF_2	169..197	CDD:285248
		EB	181..233	CDD:279949
		EGF_2	233..259	CDD:285248
		fn3	264..332	CDD:278470
		fn3	359..434	CDD:278470
		fn3	444..521	CDD:278470
		FN3	532..608	CDD:214495
		FN3	620..696	CDD:214495
		fn3	708..785	CDD:278470
		fn3	796..875	CDD:278470
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	868..888
		fn3	884..961	CDD:278470
		fn3	972..1049	CDD:278470
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1044..1063
		FN3	1060..1136	CDD:214495
		fn3	1148..1225	CDD:278470
		fn3	1236..1313	CDD:278470
		FReD	1327..1539	CDD:238040	69/187 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000