Protein Alignment CG7668 and ANGPT2

DIOPT Version :9

• Sequence 1: NP_649170.1
• Gene: CG7668 / 40190
• FlyBaseID: FBgn0036929
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001138.1
• Gene: ANGPT2 / 285
• HGNCID: 485
• Length: 496
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 120/476 - (25%)
• Similarity: 210/476 - (44%)
• Gaps: 101/476 - (21%)

  Fly    12 NSRSSPDSSTENNSSSSDSEMEFVGTSARGMLKHKKKDERKISELTRKLAEAE--INLKAQQEKG 74
            |.||| .|...:|:...|:.:|:..:..|..:.     |..:...|:.|.:.|  |....::|..
Human    52 NCRSS-SSPYVSNAVQRDAPLEYDDSVQRLQVL-----ENIMENNTQWLMKLENYIQDNMKKEMV 110

  Fly    75 SILENCIKDKDDFIKTLQLSIDLVTQTKEMT--IQKLQTQIMDLQSDLDLSRI--TIKKNDGGNC 135
            .|.:|.::::...:  :::..:|:.||.|.|  :..::.|:::..:.|:|..:  ::..|
Human   111 EIQQNAVQNQTAVM--IEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTN----- 168

  Fly   136 APAHDKVVKERKELNMENGKFREGNDQIVEIEKILNSKEAEIARLE-FKIDESKLKIV--QLEGA 197
                 |:.|:..:...|..|.::.|..:.  :|:|..::..|.:|: .|.::.:|:::  :....
Human   169 -----KLEKQILDQTSEINKLQDKNSFLE--KKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSI 226

  Fly   198 VKAKDEKIVKMTEILSEYNVNN-----KDHD--EFV--LL------GSSKLPSIKLVTLPDFEPF 247
            ::..::|||..|       |||     :.||  |.|  ||      .|:|.|::.......|...
Human   227 IEELEKKIVTAT-------VNNSVLQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDC 284

  Fly   248 ASVFE------------------------DIPSAGRGWMIIQRRIDGSFD-NATESNIITGCGDL 287
            |.||:                        |:.:.|.||.|||||.|||.| ..|......|.|:.
Human   285 AEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNP 349

  Fly   288 GGEFWLGLQKLHKMTTHRRMELYIQLVDFDNASAYARYDNFVIGDEKQKYKLLSLGEYSGNAGDA 352
            .||:|||.:.:.::|..:|..|.|.|.|::...||:.|::|.:..|:..|: :.|...:|.||..
Human   350 SGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYR-IHLKGLTGTAGKI 413

  Fly   353 FRSHINHIIVGNPFA---------------MESSKWWGTMNC---NLNGKYRNSKVELDTTDGIW 399
              |.|:.  .||.|:               |.:..||... |   ||||.|...:...:..:||.
Human   414 --SSISQ--PGNDFSTKDGDNDKCICKCSQMLTGGWWFDA-CGPSNLNGMYYPQRQNTNKFNGIK 473

  Fly   400 WGNWNVGNRYPLKSCKMLIRP 420
            |..|. |:.|.||:..|:|||
Human   474 WYYWK-GSGYSLKATTMMIRP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814	13/68 (19%)
		FReD	245..421	CDD:294064	66/219 (30%)
ANGPT2	NP_001138.1	SMC_N	<78..>295	CDD:330553	49/242 (20%)
		FBG	280..494	CDD:214548	67/221 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910