Protein Alignment CG7668 and ANGPT1

DIOPT Version :9

• Sequence 1: NP_649170.1
• Gene: CG7668 / 40190
• FlyBaseID: FBgn0036929
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001137.2
• Gene: ANGPT1 / 284
• HGNCID: 484
• Length: 498
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 122/500 - (24%)
• Similarity: 204/500 - (40%)
• Gaps: 114/500 - (22%)

  Fly    12 NSRSSPDSSTE--NNSSSSDSEMEFVGTSARGMLKHKKKDERKISELTRKLAEAEINLKAQQ--- 71
            |.|.||::|..  |..........|:.....|..:....|:...:.|.|.....|.:..:|:
Human    21 NQRRSPENSGRRYNRIQHGQCAYTFILPEHDGNCRESTTDQYNTNALQRDAPHVEPDFSSQKLQH 85

  Fly    72 -------------------------EKGSILENCIKDKDDFIKTLQLSIDLVTQTKEMT--IQKL 109
                                     |...|.:|.:::..  ...|::...|::||.|.|  :..:
Human    86 LEHVMENYTQWLQKLENYIVENMKSEMAQIQQNAVQNHT--ATMLEIGTSLLSQTAEQTRKLTDV 148

  Fly   110 QTQIMDLQSDLD-------LSRITIKK---NDGGNCAPAHDK-VVKERKELNMENGKFREGNDQ- 162
            :||:::..|.|:       ||...::|   .........|:| .:.|.|.|.|| ||.:|..|.
Human   149 ETQVLNQTSRLEIQLLENSLSTYKLEKQLLQQTNEILKIHEKNSLLEHKILEME-GKHKEELDTL 212

  Fly   163 -----------------IVEIEKILN---SKEAEIARLEFKIDESKLKIVQL---EGAV----KA 200
                             |.|:||.||   :..:.:.:.:.::.::...:|.|   ||.:    |.
Human   213 KEEKENLQGLVTRQTYIIQELEKQLNRATTNNSVLQKQQLELMDTVHNLVNLCTKEGVLLKGGKR 277

  Fly   201 KDEKIVKMTEILSEYNVNNKDHDEFVLLGSSKLPSIKLVTLPDFEPFASVFEDIPSAGRGWMIIQ 265
            ::||..:....:.:...|           .|.:.:|.:..:|  || ..||.::...|.||.:||
Human   278 EEEKPFRDCADVYQAGFN-----------KSGIYTIYINNMP--EP-KKVFCNMDVNGGGWTVIQ 328

  Fly   266 RRIDGSFD-NATESNIITGCGDLGGEFWLGLQKLHKMTTHRRMELYIQLVDFDNASAYARYDNFV 329
            .|.|||.| .........|.|:..||:|||.:.:..:|:.|:..|.|:|:|::...||::||.|.
Human   329 HREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYMLRIELMDWEGNRAYSQYDRFH 393

  Fly   330 IGDEKQKYKLLSLGEYSGNAGDAFRSHINHIIVGNPFA---------------MESSKWWGTMNC 379
            ||:|||.|:|...| ::|.||    ...:.|:.|..|:               |.:..||... |
Human   394 IGNEKQNYRLYLKG-HTGTAG----KQSSLILHGADFSTKDADNDNCMCKCALMLTGGWWFDA-C 452

  Fly   380 ---NLNGKYRNSKVELDTTDGIWWGNWNVGNRYPLKSCKMLIRPM 421
               ||||.:..:.......:||.| ::..|..|.|:|..|:|||:
Human   453 GPSNLNGMFYTAGQNHGKLNGIKW-HYFKGPSYSLRSTTMMIRPL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814	21/93 (23%)
		FReD	245..421	CDD:294064	64/194 (33%)
ANGPT1	NP_001137.2	Smc	<81..280	CDD:224117	39/201 (19%)
		FReD	281..496	CDD:238040	69/235 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910