DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7668 and Tnr

DIOPT Version :9

Sequence 1:	NP_649170.1	Gene:	CG7668 / 40190	FlyBaseID:	FBgn0036929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_037177.2	Gene:	Tnr / 25567	RGDID:	3886	Length:	1358	Species:	Rattus norvegicus

Alignment Length:	190	Identity:	64/190 - (33%)
Similarity:	94/190 - (49%)	Gaps:	32/190 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 VFEDIPSAGRGWMIIQRRIDGSFDNATE-SNIITGCGDLGGEFWLGLQKLHKMTTHRRMELYIQL 313
            |:.|:.:.|.||::.|||.:|..|...: ::...|.|:|..||||||..:|::|...|.||.:.:
  Rat  1166 VYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLDNIHRITAQGRYELRVDM 1230

  Fly   314 VDFDNASAYARYDNFVIGDEKQKYKLLSLGEYSGNAGDAFRSHINHIIVGNPFAME--------- 369
            .|...| .:|.||.|.:.|.:..|| |.:|.|:|.|||:...|     .|.||:.|
  Rat  1231 RDGQEA-VFAYYDKFAVEDSRSLYK-LRIGGYNGTAGDSLSYH-----QGRPFSTEDRDNDVAVT 1288

  Fly   370 ------SSKWWGTMNC---NLNGKYRNSKVELDTTDGIWWGNWNVGNRYPLKSCKMLIRP 420
                  ...|| ..||   ||||||..|:    .:.||.|.:|. |:.:.:...:|.:||
  Rat  1289 NCAMSYKGAWW-YKNCHRTNLNGKYGESR----HSQGINWYHWK-GHEFSIPFVEMKMRP 1342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814
CG7668	NP_649170.1	FReD	245..421	CDD:294064	64/190 (34%)
Tnr	NP_037177.2	exchanger_TraA	<190..>328	CDD:411343
		EGF_Tenascin	203..231	CDD:376143
		fn3	328..398	CDD:394996
		fn3	416..496	CDD:394996
		fn3	507..586	CDD:394996
		FN3	595..679	CDD:238020
		fn3	687..766	CDD:394996
		fn3	776..855	CDD:394996
		fn3	865..944	CDD:394996
		fn3	954..1026	CDD:394996
		FN3	1042..1127	CDD:238020
		FReD	1134..1342	CDD:238040	62/188 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900