Protein Alignment CG7668 and ANGPTL2

DIOPT Version :9

• Sequence 1: NP_649170.1
• Gene: CG7668 / 40190
• FlyBaseID: FBgn0036929
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_036230.1
• Gene: ANGPTL2 / 23452
• HGNCID: 490
• Length: 493
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 109/459 - (23%)
• Similarity: 181/459 - (39%)
• Gaps: 138/459 - (30%)

  Fly    70 QQEKGSILENCIKDKDDFI----KTLQLSIDLVTQTKEMTIQKLQTQIMDLQSDLDLSRITIKKN 130
            |:..|:|   |:..|:..:    :..:..::|:  ..|:..||  .||..||..:::
Human    63 QRVTGAI---CVNSKEPEVLLENRVHKQELELL--NNELLKQK--RQIETLQQLVEV-------- 112

  Fly   131 DGGNCAPAHDKVVKERKELNMENGKFREGNDQIVE-----IEKILNSKE--AEIARLEFKIDESK 188
            |||        :|.|.|.|..|:   |..|.::.:     :.:|:..::  .|:::||.:|....
Human   113 DGG--------IVSEVKLLRKES---RNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQT 166

  Fly   189 LKIVQLEGAVKAKD----------------EKIVKMTE--------------------------- 210
            ..::||  |.|.||                |.|.::.|
Human   167 ADMLQL--ASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPT 229

  Fly   211 ---ILSEYNVNNKDHDEFVLLGSSKLPSIKLVT-------------------LPDFEPFASVFED 253
               |:::.:.|....|:.:.:....||::..:|                   |.|....:|::..
Human   230 YNRIINQISTNEIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLV 294

  Fly   254 IP-SAGR-------------GWMIIQRRIDGS---FDNATESNIITGCGDLGGEFWLGLQKLHKM 301
            .| :..|             ||.:||||:|||   |.|  ......|.|::.||:||||:.::.:
Human   295 KPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRN--WETYKQGFGNIDGEYWLGLENIYWL 357

  Fly   302 TTHRRMELYIQLVDFDNASAYARYDNFVIGDEKQKYKLLSLGEYSGNAGDAFRSH---------- 356
            |.....:|.:.:.|:.....:|.|.:|.:..|.:.|| |.||.|.|||||:|..|
Human   358 TNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYK-LRLGRYHGNAGDSFTWHNGKQFTTLDR 421

  Fly   357 INHIIVGNPFAMESSKWW--GTMNCNLNGK-YRNSKVELDTTDGIWWGNWNVGNRYPLKSCKMLI 418
            .:.:..||....:...||  ...:.||||. ||.........||::|..:. |..|.||...|:|
Human   422 DHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFR-GGSYSLKKVVMMI 485

  Fly   419 RPMP 422
            ||.|
Human   486 RPNP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814	19/118 (16%)
		FReD	245..421	CDD:294064	62/205 (30%)
ANGPTL2	NP_036230.1	FReD	273..487	CDD:238040	63/217 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810