DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7668 and Y43C5A.2

DIOPT Version :9

Sequence 1:	NP_649170.1	Gene:	CG7668 / 40190	FlyBaseID:	FBgn0036929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_501883.1	Gene:	Y43C5A.2 / 177911	WormBaseID:	WBGene00012782	Length:	452	Species:	Caenorhabditis elegans

Alignment Length:	242	Identity:	53/242 - (21%)
Similarity:	81/242 - (33%)	Gaps:	72/242 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 DHDEFVLLGSSKLPSIKLVTLPDFEPFASVFEDIPSAGRGWMIIQRRIDGSFDNATESNI----- 280
            |..|...|.||.:.:|    .|:..| ..|:.|..|.|. :.:||.|      .||..|:
Worm   197 DCSEISNLTSSGVQTI----YPNGSP-VQVYCDTTSYGT-YTVIQSR------GATGENVNFNIT 249

  Fly   281 ------ITGCGDLGGEFWLGLQKLHKMTTHRRMELYIQLVDFDNASAYARYDNFVIGDEKQKYKL 339
                  |.|.......||.||..::.::..:...|.|.|.......|...|.:|.:|..:..|.|
Worm   250 YDKYTDIIGTPGKETNFWFGLDNMNHLSGAKPYRLQIDLCCGTLLVAKQIYHSFKVGTAEYGYNL 314

  Fly   340 LSLGEYSG----------NAGDAFRSHINHI------------------IVGNPFAMESSKWWGT 376
            .:..:.||          :.|..|.:..|..                  :...|:   ...|:|:
Worm   315 TATADISGIGLAYSSTYTDLGAKFSTFDNFTGPLGKDDCDEFQYFDDSGVQSQPY---GGWWYGS 376

  Fly   377 MNCNLNGKY---RNSK---------------VELDTTDGIWWGNWNV 405
            ...||||.:   ||..               :.:.||.|..:|.:||
Worm   377 CGNNLNGFWYPKRNGNCTVPDEVFKNTTMLGINMRTTSGQGYGGYNV 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814
CG7668	NP_649170.1	FReD	245..421	CDD:294064	46/218 (21%)
Y43C5A.2	NP_501883.1	FReD	196..438	CDD:238040	53/242 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000