DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7668 and C49C8.5

DIOPT Version :9

Sequence 1:	NP_649170.1	Gene:	CG7668 / 40190	FlyBaseID:	FBgn0036929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_501481.2	Gene:	C49C8.5 / 177668	WormBaseID:	WBGene00016769	Length:	451	Species:	Caenorhabditis elegans

Alignment Length:	249	Identity:	58/249 - (23%)
Similarity:	92/249 - (36%)	Gaps:	86/249 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 SSKLP---------SIKLVTL-PDFEPFASVFEDIPSAGRGWMIIQRR--------IDGSFDNAT 276
            ::|||         |..|.|: ||.....||:.|..::...:.|||.|        .|..|.|.:
Worm   187 TAKLPSDCDEVESTSSGLQTIYPDGSTPVSVYCDRKNSAGAYTIIQSRGREGSNITFDIPFANYS 251

  Fly   277 ESNIITGCGDLGGEFWLGLQKLHKMTTH-RRMELYIQLVDFDNASAYARYDNFVIGDEKQKYKLL 340
            :   ..|...:|..|||||..::.::|: :...|.|.|.......|...|.||.:..:.::|.|.
Worm   252 D---WFGESGVGKNFWLGLDNMNNLSTNGKTYSLQIDLCCGTQLMAKQLYTNFKVATKAEQYALT 313

  Fly   341 S------LG-EYSGNAGDAFRSHINHIIVGNPFAME--------------------------SSK 372
            :      :| :||.:|.|          :|.||:.:                          .||
Worm   314 ASADLPGIGLDYSSSAKD----------LGAPFSTQLTYSLPKGKAECDQFEFYDDDNGGAGPSK 368

  Fly   373 -----WWGTMNCNLNG-KYRNSK---------------VELDTTDGIWWGNWNV 405
                 |:|:...|||| .|.|:.               :.:.||.|...|.::|
Worm   369 GYGGWWYGSCGNNLNGFLYPNNNGDCSVTKFDSTLLLGINMRTTTGTATGGYDV 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814
CG7668	NP_649170.1	FReD	245..421	CDD:294064	50/224 (22%)
C49C8.5	NP_501481.2	FReD	190..437	CDD:294064	57/246 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000