DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7668 and tnxb

DIOPT Version :9

Sequence 1:	NP_649170.1	Gene:	CG7668 / 40190	FlyBaseID:	FBgn0036929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	XP_031747219.1	Gene:	tnxb / 100489649	XenbaseID:	XB-GENE-481849	Length:	2840	Species:	Xenopus tropicalis

Alignment Length:	211	Identity:	68/211 - (32%)
Similarity:	96/211 - (45%)	Gaps:	38/211 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 VLLGSSKLPSIKLVTLPDFEPFASVFEDIPSAGRGWMIIQRRIDGSFD---NATESNIITGCGDL 287
            :.||.||           .:|.. |:.|:.:.|.||::.||||||..|   |..:..  .|.|:|
Frog  2643 IYLGGSK-----------DDPLL-VYCDMETDGGGWIVFQRRIDGRTDFWRNWRQYK--EGFGNL 2693

  Fly   288 GGEFWLGLQKLHKMTTHRRMELYIQLVDFDNASAYARYDNFVIGDEKQKYKLLSLGEYSGNAGDA 352
            ..|||||...||::::....||.:.|.....| |||.|::|.:..|.:.:: |.:|.|.|||||:
Frog  2694 TSEFWLGNIALHRLSSLAPYELRVDLRAGAEA-AYAVYEDFRVEGEDKHFR-LRIGAYRGNAGDS 2756

  Fly   353 FRSHINHIIVGNPFAMES----------SKWWGTMNC---NLNGKYRNSKVELDTTDGIWWGNWN 404
            ...|.|.|........|.          ..|| ..||   ||||.|.|:|    ...|:.|..|.
Frog  2757 LSYHNNMIFSTRDRDAEKRILPCSISYRGAWW-YKNCHYANLNGMYGNNK----DHQGVNWHTWK 2816

  Fly   405 VGNRYPLKSCKMLIRP 420
             |..:.:...:|.:||
Frog  2817 -GFEFSIPFTEMKMRP 2831

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814
CG7668	NP_649170.1	FReD	245..421	CDD:294064	64/192 (33%)
tnxb	XP_031747219.1	EGF_Tenascin	179..206	CDD:376143
		exchanger_TraA	<400..779	CDD:411343
		EGF_Tenascin	799..826	CDD:376143
		fn3	834..913	CDD:394996
		FN3	923..998	CDD:214495
		fn3	1790..1852	CDD:394996
		fn3	1881..1960	CDD:394996
		fn3	1972..2051	CDD:394996
		fn3	2064..2141	CDD:394996
		fn3	2170..2245	CDD:394996
		fn3	2267..2338	CDD:394996
		FN3	2356..2433	CDD:238020
		fn3	2445..2522	CDD:394996
		fn3	2531..2609	CDD:394996
		FReD	2622..2831	CDD:238040	66/209 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910