DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7668 and mfap4.2

DIOPT Version :9

Sequence 1:	NP_649170.1	Gene:	CG7668 / 40190	FlyBaseID:	FBgn0036929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	XP_012826893.1	Gene:	mfap4.2 / 100488329	XenbaseID:	XB-GENE-22167947	Length:	261	Species:	Xenopus tropicalis

Alignment Length:	228	Identity:	64/228 - (28%)
Similarity:	100/228 - (43%)	Gaps:	41/228 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 YNVNNKDHDEFVLL---GSSKLPSIKLVTLPDFEPFASVFEDIPSAGRGWMIIQRRIDGSFDNA- 275
            |.:.:|:...:::.   .||.||               |:.|:.:....|.:||:|.|||...:
Frog    41 YALGSKEDGVYIIYPAGSSSALP---------------VYCDMTTDEAKWTVIQKRFDGSLSFSR 90

  Fly   276 --TESNIITGCGDLGGEFWLGLQKLHKMTTHRRMELYIQLVDFDNASAYARYDNF-----VIGDE 333
              |:..:  |.|....|:||||..::::|..::..|.|:|.||:|.:|:|.|.:|     .|..|
Frog    91 GWTDYKL--GFGRADEEYWLGLHNIYQLTLQKKYMLRIELGDFENNTAHAEYTDFSLSPNAINPE 153

  Fly   334 KQKYKLLSLGEYSGNAGDAFRSH-------INH---IIVGNPFAMESSKWW--GTMNCNLNGKYR 386
            ...|.|...|...|.|||:...|       .:|   ....|...:.||.:|  |....|:||.|.
Frog   154 DDGYTLFVDGFIDGGAGDSLTFHNGMKFSTFDHDQDTYQQNCAFLYSSGFWFKGCHLANINGPYL 218

  Fly   387 NSKVELDTTDGIWWGNWNVGNRYPLKSCKMLIR 419
            .......:.:||.|..|. |..|.||:.::.||
Frog   219 QDATYTSSGNGITWTRWK-GFNYSLKTTEIKIR 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814
CG7668	NP_649170.1	FReD	245..421	CDD:294064	58/195 (30%)
mfap4.2	XP_012826893.1	FReD	32..252	CDD:238040	64/228 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000