DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7668 and fgl2b

DIOPT Version :9

Sequence 1:	NP_649170.1	Gene:	CG7668 / 40190	FlyBaseID:	FBgn0036929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	XP_001341185.5	Gene:	fgl2b / 100001116	ZFINID:	ZDB-GENE-120709-53	Length:	1447	Species:	Danio rerio

Alignment Length:	503	Identity:	128/503 - (25%)
Similarity:	192/503 - (38%)	Gaps:	135/503 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EDQNNFSQNSRSS-PDSSTENNSSSSDSEMEFVGTSARGMLKHKKKDER----KISEL-----TR 58
            |:..|..|:..|: |.|.||..:.|       :||:.:  |:..||...    |..||     |.
Zfish   989 EEDPNIQQSGGSNVPTSGTERKTFS-------LGTADK--LERGKKGTNTPTLKKKELFKDPGTT 1044

  Fly    59 KLAEAEINLKAQQEK------GSILENCIKDKDDFIKTLQLSIDLVTQTKEMTIQKLQTQIMDLQ 117
            :...:.::....|.:      ||:....::...:..:...:|.:.:..|||:...||....:|
Zfish  1045 QFINSTVSFTDMQHRDSTKNTGSVTNAHVEMPKNVSRDTPISFESIGATKELEHIKLNKDRVD-- 1107

  Fly   118 SDLDLSRITIKKNDGGNCAPAHDKVVKERKELNMENGKFREGNDQIVEIEKILNSKEAEIARLEF 182
                               ...:.|:.....::..||...|.....|.:|.:.|::|
Zfish  1108 -------------------EIPEDVLSNPNTVDTANGYSGEKYAIPVVLETLTNTEE-------- 1145

  Fly   183 KIDESKLKIVQLEGAVKAKDEKIVKMTEILSEYNVNNKDHDEFVLLGSSKLPSIKLVTLPDFEPF 247
             |..||:..:..|...:......|. .|:.......||.|       |:.|.:....:.|..:|.
Zfish  1146 -IKGSKVFSLSPEDTAEGFKSHAVS-DEVTEREKAENKIH-------STCLGNCNTTSTPHSQPS 1201

  Fly   248 AS-------------------------------------------VFEDIPSAGRGWMIIQRRID 269
            .|                                           ||.|:.|:|.||.:||.|.|
Zfish  1202 TSQTRTPLAPEREKRPAQDCADYITKSRRNGVYRVTPRPKNTTFPVFCDMASSGGGWTLIQHRFD 1266

  Fly   270 GSFD-NATESNIITGCGDLGGEFWLGLQKLHKMTTHRRMELYIQLVDFDNASAYARYDNFVIGDE 333
            ||.. |.|......|.|.|.||||||..|:|.:|..:.|.|.|::.||:....||:||:|.|.:|
Zfish  1267 GSTSFNRTWDEYKNGFGKLIGEFWLGNDKIHLLTKAKNMSLRIEIEDFEGIREYAQYDHFYIANE 1331

  Fly   334 KQKYKLLSLGEYSGNAGDA--FRSHINH--------------IIVGNPFAMESSKWW--GTMNCN 380
            .|:|: ||:..|||.||:|  |....||              ...||..|..||.||  ..|:.|
Zfish  1332 SQQYR-LSIDGYSGTAGNAMQFSKKYNHDQKFFTTPDRDNDQYPSGNCGAYYSSGWWFDACMSAN 1395

  Fly   381 LNGKYRNSKVELDTTDGIWWGNWN--------VGNRYPLKSCKMLIRP 420
            |||||..||.: ...:||:||.|:        ...|...::.:|:|||
Zfish  1396 LNGKYYQSKYK-GVRNGIFWGTWHNITMEYYPTNERQSFRTVRMMIRP 1442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7668	NP_649170.1	DUF16	146..>212	CDD:279814	13/65 (20%)
CG7668	NP_649170.1	FReD	245..421	CDD:294064	80/246 (33%)
fgl2b	XP_001341185.5	FReD	1219..1442	CDD:238040	76/224 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810