DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gabat and PHYKPL

DIOPT Version :9

Sequence 1:NP_001163479.1 Gene:Gabat / 40188 FlyBaseID:FBgn0036927 Length:486 Species:Drosophila melanogaster
Sequence 2:XP_011532971.1 Gene:PHYKPL / 85007 HGNCID:28249 Length:460 Species:Homo sapiens


Alignment Length:496 Identity:112/496 - (22%)
Similarity:196/496 - (39%) Gaps:117/496 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 PGPKSIELKKQLDSVQATGTIQFFADYEKSI---GNYIYDVDGNILLDVYTQISSVPLGYNHPRL 100
            |...::.|:::|  :.::..:.|..|..|.:   |.|:||..|...:|..:.::.|  |:.||.:
Human     7 PKADTLALRQRL--ISSSCRLFFPEDPVKIVRAQGQYMYDEQGAEYIDCISNVAHV--GHCHPLV 67

  Fly   101 YKVFNNEQNLKTLINRPALGVFPGKEWPEKLHSVLLNIAPKGLNKITTMMC-------GSCSNEN 158
            .:. .:|||  .::|..:          ..||..:::.|.:....:...:|       ||.:|:.
Human    68 VQA-AHEQN--QVLNTNS----------RYLHDNIVDYAQRLSETLPEQLCVFYFLNSGSEANDL 119

  Fly   159 AYKSIFIWYQNKLRGNAPLTEQEKNSCMINIPPGAPKLSILSFKGAFHGRTLGALSTTHSKYIHK 223
            |           ||.....|..:               .::....|:||.....:..:..|: ..
Human   120 A-----------LRLARHYTGHQ---------------DVVVLDHAYHGHLSSLIDISPYKF-RN 157

  Fly   224 LDVPSFDW-PIASFPE-YRYPLDEN-----VAHNKKEDEKCLSEVQDLIQQYASKNPVAGIVVEP 281
            ||... :| .:|..|: ||.|..|:     :|: ..|.::.:|..|:      ....:|....|.
Human   158 LDGQK-EWVHVAPLPDTYRGPYREDHPNPAMAY-ANEVKRVVSSAQE------KGRKIAAFFAES 214

  Fly   282 IQSEGGDNEASPEFF------RSLQAIC----KKNGIALLIDEVQTGGGSTGK-FWAHEHFELES 335
            :.|.||.......:|      |....:|    :|.|...:.||:|.|.|..|| |||   |:|:.
Human   215 LPSVGGQIIPPAGYFSQVADPRVSHLLCHRHIRKAGGVFVADEIQVGFGRVGKHFWA---FQLQG 276

  Fly   336 P---PDVVTFSKKLQLGGYFHNDDFI-PNEP---------YRIFNTWMGDPGKVLLLEEVVKVIQ 387
            .   ||:||..|.:   |..|....: ..:|         ...|||:.|.|....:...|:.|::
Human   277 KDFVPDIVTMGKSI---GNGHPVACVAATQPVARAFEATGVEYFNTFGGSPVSCAVGLAVLNVLE 338

  Fly   388 EEKLLANVDVAGKVLKNGLLSLEKEFPHILNSTRGRGTFLAVN-----CTNTKVRDQ---IIGAL 444
            :|:|..:....|..|.. ||..:|....|:...||.|.|:.|:     .|.|...::   ::..|
Human   339 KEQLQDHATSVGSFLMQ-LLGQQKIKHPIVGDVRGVGLFIGVDLIKDEATRTPATEEAAYLVSRL 402

  Fly   445 KLHGI--QTGGCGEISIRFRPALIFKEYHANIVLDRFRKVL 483
            |.:.:  .|.|.|...::|:|.:.|.       ||..|:|:
Human   403 KENYVLLSTDGPGRNILKFKPPMCFS-------LDNARQVV 436

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GabatNP_001163479.1 GabT 27..484 CDD:223238 112/496 (23%)
AAT_I 27..483 CDD:302748 111/494 (22%)
PHYKPLXP_011532971.1 GabT 7..445 CDD:223238 112/496 (23%)
OAT_like 30..443 CDD:99735 108/471 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0160
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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