DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gabat and ETNPPL

DIOPT Version :9

Sequence 1:NP_001163479.1 Gene:Gabat / 40188 FlyBaseID:FBgn0036927 Length:486 Species:Drosophila melanogaster
Sequence 2:NP_112569.2 Gene:ETNPPL / 64850 HGNCID:14404 Length:499 Species:Homo sapiens


Alignment Length:442 Identity:94/442 - (21%)
Similarity:165/442 - (37%) Gaps:78/442 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 YIYDVDGNILLDVYTQISSVPLGYNHPRLYKVFNNEQNLKTLINRPALGVFPGKEWPEKLHSVLL 136
            |::|.:|...||....::.|  |:.||.:.|....:..|....:|             .||..::
Human    40 YMFDENGEQYLDCINNVAHV--GHCHPGVVKAALKQMELLNTNSR-------------FLHDNIV 89

  Fly   137 NIA-------PKGLNKITTMMCGSCSNENAYKSIFIWYQNKLRGNAPLTEQEKNSCMINIPPGAP 194
            ..|       |:.|:.......||.:|:.|.:     ...:.||:.                   
Human    90 EYAKRLSATLPEKLSVCYFTNSGSEANDLALR-----LARQFRGHQ------------------- 130

  Fly   195 KLSILSFKGAFHGRTLGALSTTHSKYIHKLDVPSFDWPIASFPE-YRYPLDENVAHNKKEDEKCL 258
              .:::...|:||.....:..:..|:....||......:|..|: ||....|:.|.:.   ....
Human   131 --DVITLDHAYHGHLSSLIEISPYKFQKGKDVKKEFVHVAPTPDTYRGKYREDHADSA---SAYA 190

  Fly   259 SEVQDLIQQ-YASKNPVAGIVVEPIQSEGGDNEASPEFFRSLQAICKKNGIALLIDEVQTGGGST 322
            .||:.:|:. :.|...:|..:.|.:||.||.......:|:.:.......|...:.||||.|.|..
Human   191 DEVKKIIEDAHNSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEYVHGAGGVFIADEVQVGFGRV 255

  Fly   323 GK-FWAHEHFELESPPDVVTFSKKLQLGGYFHN----------DDFIPNEPYRIFNTWMGDPGKV 376
            || ||:.:.:..:..||:||..|.:   |..|.          .:...:.....|||:.|:|...
Human   256 GKHFWSFQMYGEDFVPDIVTMGKPM---GNGHPVACVVTTKEIAEAFSSSGMEYFNTYGGNPVSC 317

  Fly   377 LLLEEVVKVIQEEKLLANVDVAGKVLKNGLLSLEKEFPHILNSTRGRGTFLAVNCTN-------- 433
            .:...|:.:|:.|.|..|....|..|.. ||..:|....::...||.|.|:.::...        
Human   318 AVGLAVLDIIENEDLQGNAKRVGNYLTE-LLKKQKAKHTLIGDIRGIGLFIGIDLVKDHLKRTPA 381

  Fly   434 TKVRDQIIGALKLHGI--QTGGCGEISIRFRPALIFKEYHANIVLDRFRKVL 483
            |.....||..:|...:  ...|.....::.:|.:.|.|..|..::|:..::|
Human   382 TAEAQHIIYKMKEKRVLLSADGPHRNVLKIKPPMCFTEEDAKFMVDQLDRIL 433

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GabatNP_001163479.1 GabT 27..484 CDD:223238 94/442 (21%)
AAT_I 27..483 CDD:302748 93/440 (21%)
ETNPPLNP_112569.2 PRK06148 <6..441 CDD:180426 94/442 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 468..499
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0160
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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