Protein Alignment Gabat and ABAT

DIOPT Version :9

• Sequence 1: NP_001163479.1
• Gene: Gabat / 40188
• FlyBaseID: FBgn0036927
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001373544.1
• Gene: ABAT / 18
• HGNCID: 23
• Length: 532
• Species: Homo sapiens
• Alignment Length: 486
• Identity: 251/486 - (51%)
• Similarity: 337/486 - (69%)
• Gaps: 34/486 - (6%)

  Fly    31 PVVKTKSIPGPKSIELKKQLDSVQATGTIQFFADYEKSIGNYIYDVDGNILLDVYTQISSVPL-- 93
            |::||: :|||:|.||.|||:.:|....:.||.:||:|.|||:.|||||.:||:|:||||||:
Human    44 PLMKTE-VPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIEM 107

  Fly    94 ------------------------------GYNHPRLYKVFNNEQNLKTLINRPALGVFPGKEWP 128
                                          ||:||.|.|:....||....:||||||:.|.:.:.
Human   108 VVSLCAAQAGLELLDSSDPPTLASQSARISGYSHPALLKLIQQPQNASMFVNRPALGILPPENFV 172

  Fly   129 EKLHSVLLNIAPKGLNKITTMMCGSCSNENAYKSIFIWYQNKLRGNAPLTEQEKNSCMINIPPGA 193
            |||...||::||||::::.||.|||||||||.|:||:||::|.||....:::|..:||||..||.
Human   173 EKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGC 237

  Fly   194 PKLSILSFKGAFHGRTLGALSTTHSKYIHKLDVPSFDWPIASFPEYRYPLDENVAHNKKEDEKCL 258
            |..|||||.|||||||:|.|:|||||.|||:|:||||||||.||..:|||:|.|..|::|:.:||
Human   238 PDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCL 302

  Fly   259 SEVQDLIQQY-ASKNPVAGIVVEPIQSEGGDNEASPEFFRSLQAICKKNGIALLIDEVQTGGGST 322
            .||:|||.:| ..|..||||:|||||||||||.||.:|||.|:.|.:|:|.|.|:||||||||.|
Human   303 EEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCT 367

  Fly   323 GKFWAHEHFELESPPDVVTFSKKLQLGGYFHNDDFIPNEPYRIFNTWMGDPGKVLLLEEVVKVIQ 387
            ||||||||:.|:.|.||:|||||:..||:||.::|.||.||||||||:|||.|.|||.||:.:|:
Human   368 GKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIK 432

  Fly   388 EEKLLANVDVAGKVLKNGLLSLEKEFPHILNSTRGRGTFLAVNCTNTKVRDQIIGALKLHGIQTG 452
            .|.||.|...|||.|..|||.|:..:|..::..||||||.:.:..:..:|:::|...:..|:..|
Human   433 REDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLG 497

  Fly   453 GCGEISIRFRPALIFKEYHANIVLDRFRKVL 483
            |||:.||||||.|:|:::||::.|:.|..:|
Human   498 GCGDKSIRFRPTLVFRDHHAHLFLNIFSDIL 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gabat	NP_001163479.1	GabT	27..484	CDD:223238	251/486 (52%)
		AAT_I	27..483	CDD:302748	250/484 (52%)
ABAT	NP_001373544.1	GABAtrns_euk	34..528	CDD:129782	250/484 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143328
Domainoid	1	1.000	516	1.000	Domainoid score	I309
eggNOG	1	0.900	-	-		E1_COG0160
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H542
Inparanoid	1	1.050	539	1.000	Inparanoid score	I1194
Isobase	1	0.950	-	0	Normalized mean entropy	S672
OMA	1	1.010	-	-		QHG55983
OrthoDB	1	1.010	-	-		D222188at33208
OrthoFinder	1	1.000	-	-		FOG0005369
OrthoInspector	1	1.000	-	-		oto88582
orthoMCL	1	0.900	-	-		OOG6_103520
Panther	1	1.100	-	-	LDO	PTHR43206
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R468
SonicParanoid	1	1.000	-	-		X3808
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750