DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gabat and Phykpl

DIOPT Version :9

Sequence 1:	NP_001163479.1	Gene:	Gabat / 40188	FlyBaseID:	FBgn0036927	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_038940910.1	Gene:	Phykpl / 100169747	RGDID:	2293818	Length:	503	Species:	Rattus norvegicus

Alignment Length:	492	Identity:	113/492 - (22%)
Similarity:	186/492 - (37%)	Gaps:	120/492 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SIELKKQLDSVQATGTIQFFADYEKSI----GNYIYDVDGNILLDVYTQISSVPLGYNHPRLYKV 103
            :::|:::|.|   :....||.:....|    |.|:||..|...||....::.|  |:.||.:.:.
  Rat    11 TLDLRRRLLS---SSCRLFFPENPVKIIRGQGQYLYDEQGREYLDCINNVAHV--GHCHPTVVQA 70

  Fly   104 FNNEQNLKTLINRPALGVFPGKEWPEKLHSVLLNIA-------PKGLNKITTMMCGSCSNENAYK 161
             .:||||....|            ...||..:::.|       |:.|:....:..||.:|:.|.:
  Rat    71 -AHEQNLVLNTN------------SRYLHDNIVDYAQRLSETLPEKLSVFYFLNSGSEANDLALR 122

  Fly   162 SIFIWYQNKLRGNAPLTEQEKNSCMINIPPGAPKLSILSFKGAFHGRTLGALSTTHSKYIHKLDV 226
                           |..|.         .|...:.:|..  |:||.....:..:..|: ..||.
  Rat   123 ---------------LARQY---------TGHQDVVVLDH--AYHGHLSSLIDISPYKF-RNLDG 160

  Fly   227 PSFDW-PIASFPE-YRYPLDENVAHNKKEDE-----KCLSEVQDLIQQYASK-NPVAGIVVEPIQ 283
            .. :| .:|..|: ||.|.        :||.     ...|||:.:|.....| ..:|....|.:.
  Rat   161 QK-EWVHVAPLPDTYRGPY--------REDHPDPAGAYASEVKHVISSAQKKGRKIAAFFAESLP 216

  Fly   284 SEGGDNEASPEFFRSLQAICKKNGIALLIDEVQTGGGSTGK-FWAHEHFELESP---PDVVTFSK 344
            |..|.......:|..:....::.|...:.||:|.|.|..|| |||   |:||..   ||:||..|
  Rat   217 SVSGQIIPPAGYFSQVAEHIRRAGGLFVADEIQVGFGRVGKHFWA---FQLEGEDFVPDIVTMGK 278

  Fly   345 KLQLGGYFHNDDFIPNEP------------------YRIFNTWMGDPGKVLLLEEVVKVIQEEKL 391
            .:..|           .|                  ...|||:.|:|....:...|:.|::.|:|
  Rat   279 SIGNG-----------HPVACLATTQAVSRAFEATGVEYFNTFGGNPVSCAVGLAVLDVLKTEQL 332

  Fly   392 LANVDVAGKVLKNGLLSLEKEFPHILNSTRGRGTFLAVNCTN--------TKVRDQIIGALKLHG 448
            .|:....|..|...|...:.:.| |:...||.|.|:.|:...        |:..:.::..||.:.
  Rat   333 QAHATNVGSFLMEHLSQQKAKHP-IIGDVRGTGLFIGVDLIKDETLRTPATEEAEYLVSRLKENY 396

  Fly   449 I--QTGGCGEISIRFRPALIFKEYHANIVLDRFRKVL 483
            |  .|.|.|...::|:|.:.|...:|..|:.:...:|
  Rat   397 ILLSTDGPGRNILKFKPPMCFSLDNAQHVVAKLDDIL 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gabat	NP_001163479.1	GabT	27..484	CDD:223238	113/492 (23%)
Gabat	NP_001163479.1	AAT_I	27..483	CDD:302748	112/490 (23%)
Phykpl	XP_038940910.1	PRK06148	<6..433	CDD:180426	112/490 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810