Protein Alignment CG7646 and Ncs1

DIOPT Version :10

• Sequence 1: NP_649167.1
• Gene: CG7646 / 40187
• FlyBaseID: FBgn0036926
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_077342.1
• Gene: Ncs1 / 65153
• RGDID: 68417
• Length: 190
• Species: Rattus norvegicus
• Alignment Length: 190
• Identity: 83/190 - (43%)
• Similarity: 114/190 - (60%)
• Gaps: 11/190 - (5%)

  Fly     1 MGCLSSKDRLTKEDMEFLKTHTRYDEATIKEWYKGFKQDCPNGRLTPAKFVDMYKMFFPSGNAEE 65
            ||  .|..:|..|.:|.|...|.:.|..:::|||||.:|||:|:|..|.|..:||.|||.|:..:
  Rat     1 MG--KSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTK 63

  Fly    66 FCDHVFRTFDMDKNGYIDFKEFLLAIDVTSSGTPEEKLKWAFRMYDVDGNGVIDIQEMTKIVQAI 130
            |...||..||.:|:|.|:|.||:.|:.|||.||.:|||:|||::||:|.:|.|...||..||.||
  Rat    64 FATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAI 128

  Fly   131 YDMLGAC-----SSNRPADSAEERAKNIFAKMDENNDGQLTQDEFLKGCLQDEELSKMLA 185
            |.|:|..     ..|.|    |:|...|||.||:|.||:||..||.:|...|..:.:.|:
  Rat   129 YQMVGNTVELPEEENTP----EKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALS 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7646	NP_649167.1	FRQ1	42..176	CDD:444056	64/138 (46%)
Ncs1	NP_077342.1	FRQ1	22..174	CDD:444056	73/155 (47%)
		Ancestral calcium site 1	36..47		5/10 (50%)
		Interaction with IL1RAPL1. /evidence=ECO:0000250|UniProtKB:P62166	174..190		2/11 (18%)